生物物理學[龐小峰主編書籍]

生物物理學[龐小峰主編書籍]

生物物理學( Biological Physics)是物理學與生物學相結合的一門交叉學科,是生命科學的重要分支學科和領域之一。 生物物理學是套用物理學的概念和方法研究生物各層次結構與功能的關係、生命活動的物理、物理化學過程和物質在生命活動過程中表現的物理特性的生物學分支學科。生物物理學旨在闡明生物在一定的空間、時間內有關物質、能量與信息的運動規律。 本教材重點介紹了作為生物物理學的物質基礎的細胞的結構與功能,以及建立在這個基礎上的腦和神經系統、視覺和聽覺系統及血液循環系統等幾大主要生物學系統的結構、組成、特性和功能。同時對當前生物物理學關心的自由基、生物能力學、生物組織的特性及形成等幾個基本問題作了較為詳細的介紹。 適合於本科生和研究生的教學,但因對象不同,可取捨不同的內容和採用不同的學時進行講述。

書籍信息

作 者:龐小峰 ISBN: 978−7–5647–1418–5
出版時間:13-01-02

•版 次:第一版

•頁 數:306

•字 數:398千字

•印刷時間:13-01-02

•開 本:16開

•紙 張:書寫紙

•印 次:1

•包 裝:平裝

內容簡介

本教材重點介紹了作為生物物理學的物質基礎的細胞的結構與功能,以及建立在這個基礎上的腦和神經系統、視覺和聽覺系統及血液循環系統等幾大主要生物學系統的結構、組成、特性和功能。同時對當前生物物理學關心的自由基、生物能力學、生物組織的特性及形成等幾個基本問題作了較為詳細的介紹。

適合於本科生和研究生的教學,但因對象不同,可取捨不同的內容和採用不同的學時進行講述。

圖書目錄

第一章 細胞的結構、特性與功能................................................................................. 1

第一節 細胞核的結構與功能··················································································· 1

一、核質·················································································································· 1

二、核仁·················································································································· 2

三、核被膜·············································································································· 3

四、有絲分裂及染色體的超微結構······································································· 3

第二節 細胞質的結構及生物功能··········································································· 3

一、核糖體和多核糖體··························································································· 4

二、內質網(ER)·································································································· 4

三、高爾基複合器(高爾基器) ··········································································· 5

四、溶酶體·············································································································· 6

五、過氧化小體(微體) ······················································································· 7

六、線粒體·············································································································· 7

第三節 細胞膜及其成分························································································· 10

一、膜脂················································································································ 10

二、膜蛋白············································································································ 13

三、膜糖蛋白是一種蛋白質與糖類的共價複合物·············································· 17

四、N-GlcNAc 連線型聚糖················································································ 17

第四節 生物膜的特性及分子結構模型·································································· 18

一、生物膜的基本特徵························································································· 18

二、膜的分子結構模型························································································· 21

三、膜的液晶模型································································································· 22

第五節 細胞的通透性和離子與分子的被動轉移·················································· 24

一、水的通透性和通道························································································· 24

二、非電介質的通透性························································································· 27

三、有轉運載體參與下的被動轉運或易化擴散·················································· 28

四、Na+,K+,Ca2+和Mg2+及Cl-等離子的通透性·········································· 30

五、離子通道的形成及其結構············································································· 33

第六節 主動轉運和離子泵及其他運輸機制·························································· 38

一、非電解質的主動轉運效應及離子泵······························································ 38

二、鈉泵················································································································ 39

三、鈣泵················································································································ 41

四、生物膜的其他主動轉運方式········································································· 41

五、離子梯度驅動的主動運輸············································································· 42

六、胞吞運輸········································································································ 42

第二章 神經生物物理學基礎....................................................................................... 45

第一節 神經系統、大腦、神經細胞、突觸和神經遞質······································ 45

一、神經系統和大腦皮層····················································································· 45

二、神經細胞和突觸····························································································· 47

三、神經遞質和調質····························································································· 52

第二節 神經興奮及其特性····················································································· 54

一、神經的興奮狀態····························································································· 54

二、靜息電位········································································································ 56

三、動作電位········································································································ 57

四、興奮膜在興奮時的性能變化········································································· 61

五、神經信號的特性····························································································· 63

第三節 神經興奮在神經纖維中的傳遞·································································· 66

一、神經纖維系統································································································· 66

二、神經興奮的傳導理論····················································································· 67

三、神經興奮與大腦的活動················································································· 73

第四節 非傳播的突觸後電位興奮········································································· 75

一、化學突觸的突觸前和後過程········································································· 76

二、神經-肌肉突觸興奮的特點··········································································· 77

三、化學突觸後電位的機制················································································· 81

四、乙醯膽鹼(Ach)的循環過程······································································· 82

五、電突觸的特性································································································· 83

第五節 由受體介導的神經信號轉導····································································· 84

一、膜受體及特性································································································· 84

二、由G 蛋白偶聯受體介導的神經信號的跨膜轉導效應·································· 86

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