學習工作簡歷
受教育經歷
2000/09– 2005/06,中國海洋大學,海洋生命學院,博士
1996/09– 2000/06,煙臺大學,化學生物理工學院,學士
研究工作經歷
2005/09 –2009/02,中國海洋大學,海洋生命學院,講師
2009/03– 2010/02,美國國立衛生研究院,癌症研究所,博士後
2010/03– 2011/06 ,中國海洋大學,海洋生命學院,講師
2011/07– 2012/03,美國國立衛生研究院,癌症研究所,交流訪問
2012/04–,中國海洋大學,海洋生命學院,講師
科研領域描述
(1)海洋生物酶類產生菌的篩選、發酵、酶的分離純化,活性及作用機理研究
(2)殼聚糖基納米材料在基因遞送中的套用
(3)載基因殼聚糖納米複合物在疾病的基因治療中的套用研究
代表性成果
[1]Liu J, Cai W,Liu W,Han B,Chang J,Yang Y. ModulationofliverL-glutamyl -L-cysteinylglycinehomeostasisbyN-acetyl-glucosamine-thiazolidine-4(R)-carboxylic acidinmice. Am J Med Sci.343(4): 310-5,2012.
[2]Yang Yan, Liu Ying, Yao Xiaohong, Huang Jian, Wang Jiming. Annexin 1 released by necrotic human glioblastoma cells stimulates tumor cell growth through formyl peptide receptor 1. American Journal of Pathology, 179(3):1504-12,2011.
[3]Ying Liu,Yan Yang,Xiaohong Yao,Jian Huang,Wanghua Gong,Keqiang Chen1,Xiuwu Bian,Ji Ming Wang.Identification of Annexin 1 (Anx A1) as a necrotic glioblastoma cell-derived chemotactic agonist for the G protein- coupled receptor FPR (FPR1) Cytokine, 52(1–2):24–25,2011.
[4]張沛,韓寶芹,陳列歡,彭燕飛,劉萬順,楊艷,用酶法製備殼寡糖及其對機體免疫功能的調節作用。中國免疫學雜誌,28(1):8-13,2013.
[5]Chenghua Guo, Xuexi Tang, Xinwei Dong, Yan Yang. Studies on the expectorant, antitussive and antiasthmatic properties of asterosaponin extracted from Luidis quinaria. African Journal of Biotechnology. 2009;8(23): 6694-9996.
[6]Yang Yan, Liu Wanshun, Han Baoqin, Wang Changhong, Fu Chenwei, Liu Bing, Chen Liehuan. The antioxidative and immunostimulating properties of D-glucosamine. International Immunopharmacology, 2007;7:29-35.
[7]Chun L. Li, Yan Yang, Bao Q. Han, Wan S. Liu. Antioxidant activity of N-acetyl-glucosamine based thiazolidine derivative. High-tech Letters. 2007;13:15-21
[8]Yang Yan, Liu Wan-Shun, Han Bao-Qin, Sun Hai-Zhou. Antioxidative Properties of a newly synthesized 2-glucosamine-thiazolidine-4(R)- Carboxylic Acid (GlcNHCys) in mice. Nutrition Research, 2006;26: 369-377.
[9]Yang Yan, Liu Wanshun, Han Baoqin, Liu Bing, Fu Chenwei. Protective effects of chitosan oligosaccharide and its derivatives against carbon tetrachloride induced liver damage in mice. Hepatology Research, 2006;35:178-184.
[10]Jin Liming, Liu Wanshun, Han Baoqin, Yang Yan, Tian Wenjie, Fan Shengdi. Factors influencing the in vitro culture of osteoblasts. Chinese Jounal of Clinical Rehabilitation. 2006,20(9):190-192.
[11]Yang Yan, Liu Wanshun, Han Baoqin, Fu Chenwei, Sun Haizhou. Synthesis of two new thiazolidines and evaluation of their hepatoprotective effects. High-tech Letters, 2005;11 (1): 437-442
[12]Yang Yan, Liu Wanshun, Han Baoqin, Sun Mingkun, Zheng Qiusheng. Antioxidative Properties of 2-Substituted-Thiazolidine-4(R)-Carboxylic Acids. ACTA Biochimica et Biophysica Sinica. 2003 (35): 11
[13]金黎明,楊艷,劉萬順,韓寶芹,田文杰,范聖第。殼寡糖及其衍生物對CCl4誘導的小鼠肝損傷的保護作用。山東大學學報(理學版)2007;42(7):1-5
[14]付辰煒,劉萬順,韓寶芹,楊艷,劉冰。氨基葡萄糖對小鼠免疫功能的影響。營養學報,2007;29(1):51-55
[15]劉吉,蔡文迪,楊艷,劉萬順,韓寶芹,常菁。噻唑烷酸提高肝組織GSH含量功能的研究。中國海洋大學學報