主要研究方向
主要集中在新型抗結核藥物的篩選及其作用靶標的分析與驗證。
代表性論文和專著
1. Zhang XL, Hu YW, Chen SD, et al. (2009). Synthesis and evaluation of (S, S)-N, N'-bis-[3-(2, 2', 6, 6'-tetramethylbenzhydryloxy)-2-hydroxy-propyl]-ethylenediamine (S2824) analogs with anti-tuberculosis activity.Bioorganic & Medicinal Chemistry Letters19 (21):6074-6077.
2. Zhang XL, Chen SD, Hu ZD, et al. (2009). Expression and Characterization of Two Functional Methionine Aminopeptidases from Mycobacterium tuberculosis H37Rv.Current Microbiology 59(5):520-525.
3. Qie YQ, Wang JL, Liu Wei,... Zhang XL*, Wang HH*(2009).More Vaccine Efficacy Studies on the Recombinant Bacille Calmette-Guerin Co-expressing Ag85B, Mpt64190–198 and Mtb8.4. 1:Scand J Immunol. Apr;69(4):342-50.
4. Lai XH, Wu J, Chen SD, Zhang XL*, Wang HH*.(2008). Expression, purification, and characterization of a functionally active Mtb UDP–Glucose Pyrophosphorylase.Protein Expression and Purification, (61):50-56
