人物經歷
1980年－1984年 蘭州大學化學系本科；1984年－1987年 蘭州大學化學系碩士；1997年－2002年 天津大學化工學院博士；1987年－1997年 天津大學套用化學系；1997年－至今 天津大學化工學院
講授課程
《高分子化學》，《高分子導論》，《高分子科學進展》
研究方向:
主要研究領域為功能高分子，包括生物醫用高分子材料和環境友好高分子材料。生物醫用高分子方向，從仿生的理念出發，基於多糖及蛋白質的改性，研究開發與組織工程、再生醫學、藥物控釋、及幹細胞治療等領域相關的生物材料；環境友好高分子方向主要研究生物降解、光降解高分子材料的設計、合成及改性。
主要項目
科研項目:
國家基金 “基於木葡聚糖基水凝膠的防術後粘連及相關分子機制研究”，在研
企業合作 “聚乳酸生物醫用膜的研究開發”，在研
國家基金 “生物惰性－生物活性雙重功能材料與幹細胞微環境”， 在研
國家基金 “多糖基兩性離子聚合物與基因工程細胞微囊化裝載體系”， 已完成
國家基金 “多相多組分複雜支架的製備與其對細胞行為的調控”，已完成
國家基金 “組織工程相關中藥釋放系統”， 已完成
企業合作 “生物降解聚合物的研究開發”， 已完成
企業合作 “聚乳酸類不對稱膜的研究”， 已完成
企業合作 “聚合物-羥基磷灰石複合材料的研究開發“，已完成
科研成果
獲天津市科學技術進步三等獎、二等獎; 天津市產學研突出貢獻一等獎; 獲得國家發明專利6項。
論著專利:
專著：
[1] Kangde Yao, Junjie Li，Fanglian Yao, Yuji Yin. Chitosan based material and their applications, CRC Press USA 2008 (ISBN: 978-1-4200-4372-3).
[2] Kangde Yao, Junjie Li, Fanglian Yao, Yuji Yin. Chitosan based Hydrogels: Function and Application. CRC Press, USA， 2011. (ISBN: 978-1-4398-2114-5).
[3] Wen Yan, Zhang Xiaoyang, Li Lina, Yao Fanglian. Dendrimer-Based Nanocarriers for Drug Controlled Release and Targeted Delivery, Dendrimer-Based Nanocarriers for Drug Controlled Release and Targeted Delivery. Nova Publishers, New York, 2013.
科技論文：
1.
1.Fang, WC; Zhang, H ; Yin, JW; Yang, BG ; Zhang, YB ; Li, JJ ; Yao, FL. Hydroxyapatite Crystal Formation in the Presence of Polysaccharide . CRYSTAL GROWTH & DESIGN, 16 (3):1247-1255 (2016).
2.Ye, L ; Zhan, YB; Yang, BG; Zhou, X; Li, JJ; Qin, ZH; Dong, DY; Cui, YL; Yao, FL. Zwitterionic-Modified Starch-Based ealth Micelles for Prolonging Circulation Time and Reducing Macrophage Response. ACS APPLIED MATERIALS & INTERFACES, 8 (7): 4385-4398 (2016).
3.Dong, DY; Li, JJ; Cui, M; Wang, JM; Zhou, YH; Luo, L; Wei, YF; Ye, L; Sun, H; Yao, FL. In Situ "Clickable" Zwitterionic Starch-Based Hydrogel for 3D Cell Encapsulation. ACS APPLIED MATERIALS & INTERFACES, 8 (7): 4442-4455 (2016).
4.Yang, BG; Yao, FL; Hao, T; Fang, WC; Ye, L; Zhang, YB; Wang, Y; Li, JJ; Wang, CY. Development of Electrically Conductive Double-Network Hydrogels via One-Step Facile Strategy for Cardiac Tissue Engineering. ADVANCED HEALTHCARE MATERIALS, 5 (4): 474-488 (2016).
5.Wang, Y; Li, LN; Li, JJ; Yang, BG; Wang, CY; Fang, WC; Ji, F; Wen, Y; Yao, FL. Stable and pH-responsive polyamidoamine based unimolecular micelles capped with a zwitterionic polymer shell for anticancer drug delivery. RSC ADVANCES, 6 (21): 17728-17739 (2016).
6. Zhang, ES; Zhu, CS; Yang, J; Sun, H; Zhang, XM; Li, SH; Wang, YL; Sun, L; Yao, FL. Electrospun PDLLA/PLGA composite membranes for potential application in guided tissue regeneration. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 58: 278-285 (2016).
7.Wang, JM; Li, JJ; Yang, HM; Zhu, CS; Yang, J; Yao, FL. Preparation and characterization of protein resistant zwitterionic starches: The effect of substitution degrees. STARCH-STARKE, 67 (11-12): 920-929 (2015).
8. Li, JJ; Yang, BG; Qian, YF; Wang, QY; Han, RJ; Hao, T; Shu, Y; Zhang, YB; Yao, FL. Iota-carrageenanichitosanigelatin scaffold for the osteogenic differentiation of adipose-derived MSCs in vitro. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 103 (7): 1498-1510 (2015).
9. Zhang, YB; Ye, L; Cui, J; Yang, BG; Sun, H; Li, JJ; Yao, FL. A Biomimetic Poly (vinyl alcohol)-Carrageenan Composite Scaffold with Oriented Microarchitecture. ACS Biomater. Sci. Eng., 2 (4), 544–557 (2016).
10. Wang Jinmei，Sun Hong，Li Junjie，Dong Dianyu，Zhang Yabin，Yao Fanglian*.Ionic starch-based hydrogels for the prevention of nonspecific protein adsorption，Carbohydrate Polymers，2015，117：384-391。
11. Li Lina，Wang Yan，Ji Feng，Wen Yan，Li Junjie，Yang Boguang，Yao Fanglian*，Synthesis and characterization of dendritic star-shaped zwitterionic polymers as novel anticancer drug delivery carriers，Journal of Biomaterials Science, Polymer Edition，2014，25（14-15）：1641-1657.
12. Wen Yan，Yao Fanglian*，Sun Fang，Tan Zhilei，Antibacterial action mode of quaternized carboxymethyl chitosan/poly(amidoamine) dendrimer core–shell nanoparticles against Escherichia coli correlated with molecular chain conformation，Materials Science and Engineering: C,2015，48：220-227.
13. Tian Miao，Wang Jinmei，Zhang Ershuai，Li Junjie，Duan Cuimi，Yao Fanglian*，Synthesis of Agarose-graft-poly[3-dimethyl (methacryloyloxyethyl) ammonium propanesulfonate] Zwitterionic Graft Copolymers via ATRP and Their Thermally-Induced Aggregation Behavior in Aqueous Media，Langmuir，2013，29（25）：8076-8085.
14. Li Junjie，Yang Boguang，Qian Yufeng，Yao Fanglian*，Wang Changyong，Iota-carrageenan/chitosan/gelat in scaffold for the osteogenic differentiation of adipose-derived MSCs in vitro，Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2015
15. Li Junjie, Guo Shuangzhuang, Wang Min, Ye Lei, Yao Fanglian*，Poly (lactic acid)/Poly (ethylene glycol) Block Copolymer Based Shell or Core Cross-linked Micelles for Controlled Release of Hydrophobic Drug，RSC Adv，2015，5（2）：19484-19492
16. Tian Liang，Yang Jing，Ji Feng，Liu Yuxi，Yao Fanglian*，Drug co-loading and pH-sensitive release core-shell nanoparticles via layer-by-layer assembly，Journal of Biomaterials Science, Polymer Edition，2014，25（14-15）：1573-1589.
17. Zhang Xiaoyang，Zhao Jun，Wen Yan, Yao Fanglian*. Carboxymethyl chitosan-poly(amidoamine) dendrimer core-shell nanoparticles for intracellular lysozyme delivery. CARBOHYDRATE POLYMERS, 98 (2): 1326-1334, 2013.
18. Tian Miao, Wang Jinmei, Zhang Ershuai, Yao Fanglian*. Synthesis of Agarose-graft-poly[3-dimethyl (methacryloyloxyethyl) ammonium propanesulfonate] Zwitterionic Graft Copolymers via ATRP and Their Thermally-Induced Aggregation Behavior in Aqueous Media. LANGMUIR, 29 (25): 8076-8085, 2013
19. Yang YU, Hong ZHANG, Hong SUN, Dandan XING, Fanglian YAO*. Nano-hydroxyapatite formation via co-precipitation with chitosan-g-poly(N-isopropylacrylamide) in coil and globule states for tissue engineering application. Front. Chem. Sci. Eng., 7(4): 388–400, 2013.
20. Liu YX, Yang J, Zhao ZQ, Li JJ, Zhang R, Yao FL. Formation and characterization of natural polysaccharide hollow nanocapsules via template layer-by-layer self-assembly. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 379, 130-140(2012).
專利：
[1] 姚芳蓮，李俊傑，尹建偉，劉玉璽. 多組分骨組織工程支架材料及其製備方法，中國發明專利， 2011110300132650
[2] 姚芳蓮，於瀟，張彬，姚康德. 殼聚糖或/和明膠－聚乳酸共混物三維多孔支架的製備方法，中國發明專利，200610016190.1
[3] 姚芳蓮， 孫達， 王慧， 黃志琦. 殼聚糖基光交聯水凝膠的製備方法， 中國發明專利， 2011112300605180
[4] 姚芳蓮，於瀟，張彬，姚康德. 殼聚糖－聚乳酸共聚物三維多孔支架的製備方法，中國發明專利， 200610016189.9
[5] 姚芳蓮，劉玉璽，楊靜. 天然多糖基納米微囊的製備方法，中國發明專利，2012030100179570 .
