簡介
早在2003年，南華大學醫學院生理學科就開展了一系列認知神經科學和神經變性病的研究，經近10年的不斷探索，已成為湖南省內一支重要的神經科學研究隊伍，是中國生理學會理事單位以及湖南省生理科學會副理事長單位。在不斷創新與開拓過程中，本所形成了認知障礙性疾病和神經變性疾病兩個研究水平省內領先的科研主攻方向。
研究方向
認知障礙性疾病
神經變性疾病
近年來發表的SCI文章
| 序號 | 第一作者 / 通訊作者 * | 論文名稱 | 刊物 | 年度 |
| 1 | 唐小卿 | A novel mechanism of formaldehyde neurotoxicity: inhibition of hydrogen sulfide generation by promoting overproduction of nitric oxide. | PLoS One | 2013 |
| 2 | 唐小卿 | Formaldehyde impairs learning and memory involving the disturbance of hydrogen sulfide generation in the hippocampus of rats | J Mol Neurosci. | 2013 |
| 3 | 唐小卿 | Role of Paraoxonase-1 in the Protection of Hydrogen Sulfide-Donating Sildenafil (ACS6) Against Homocysteine-Induced Neurotoxicity | J Mol Neurosci. | 2013 |
| 4 | 唐小卿 | Hydrogen sulfide prevents formaldehyde-induced neurotoxicity to PC12 cells by attenuation of mitochondrial dysfunction and pro-apoptotic potential. | Neurochem Int | 2012 |
| 5 | 唐小卿 | Involvement of K(ATP)/PI (3)K/AKT/Bcl-2 pathway in hydrogen sulfide-induced neuroprotection against the toxicity of 1-methy-4-phenylpyridinium ion. | J Mol Neurosci. | 2012 |
| 6 | 凌宏艷 | MiRNA-21 reverses high glucose and high insulin induced insulin resistance in 3T3-L1 adipocytes through targeting phosphatase and tensin homologue. | Experimental and Clinical Endocrinology & Diabetes. | 2012 |
| 7 | 凌宏艷/ 胡弼* | Arecoline improves vascular endothelial function in high fructose-fed rats via increased CSE expression and activation of KATP channels. | Acta Pharmacol Sinica. | 2012 |
| 8 | 凌宏艷 | The role of epigenetic regulation in diabetes and its complications | Prog Biochem Biophys. | 2012 |
| 9 | 顧洪豐 | Psychological stress, immune response and atherosclerosis | Atherosclerosis | 2012 |
| 10 | 唐小卿 | Inhibition of hydrogen sulfide generation contributes to 1-methy-4- phenylpyridinium ion-Induced neurotoxicity | Neurotoxicity Research | 2011 |
| 11 | 唐小卿 | Formaldehyde induces neurotoxicity to PC12 cells involving inhibition of paraoxonase-1 expression and activity | Clin Exp Pharmacol Physiol. | 2011 |
| 12 | 唐小卿 | Inhibition of endogenous hydrogen sulfide generation is associated with homocysteine-induced neurotoxicity: role of ERK1/2 activation | J Mol Neurosci | 2011 |
| 13 | 唐小卿 | Endogenous hydrogen sulfide is involved in asymmetric dimethylarginine-induced protection against neurotoxicity of 1-methyl-4-phenyl-pyridinium Ion | Neurochem Res | 2011 |
| 14 | 田紹文 | Nicotine enhances contextual fear memory reconsolidation in rats. | Neuroscience Letters | 2011 |
| 15 | 田紹文 | Ventrolateral prefrontal cortex is required for fear extinction in a modified delay conditioning paradigm in rats | Neuroscience | 2011 |
| 16 | 歐陽新平/田紹文* | Rapid eye movement sleep deprivation disrupts context-modulated effects on morphine locomotor sensitization in mice | Neuroscience Letters | 2011 |
| 17 | 凌宏艷 | MicroRNA-375 promotes 3T3-L1 adipocyte differentiation through modulation of extracellular signal-regulated kinase signalling | Clin Exp Pharmacol Physiol. | 2011 |
| 18 | 周壽紅 | Subtoxicdose of chlorpyrifos down regulates ABCA1 expression and accelerates formation of atherosclerosis Induced by the high fat diet inNew Zealandrabbits | Prog Biochem Biophys. | 2011 |
| 19 | 顧洪豐 | Curcumin alleviates neuropathic pain through decreasing the expressions of proinflammatory cytokines produced by TLR4 pathway in the spinal cord of rats | Prog Biochem Biophys. | 2011 |
| 20 | 唐小卿 | Neuroprotective effect of asymmetric dimethylarginine against 1-methyl-4-phenylpyridinium ion-induced damage in PC12 cells | Clin Exp Pharmacol Physiol. | 2010 |
| 21 | 唐小卿 | Hydrogen sulfide antagonizes homocysteine-induced neurotoxicity in PC12 cells | Neuroscience Research | 2010 |
| 22 | 唐小卿* | Daxx mediates oxidized low density lipoprotein induced cholesterol accumulation and apoptosis in macrophages by upregulating caveolin expression | Prog Biochem Biophys. | 2010 |
| 23 | 田紹文 | Antidepressant- and anxiolytic effects of the novel melatonin agonist Neu-P11 inrodent models | Acta Pharmacologica Sinica | 2010 |
| 24 | 周壽紅 | Paraoxon attenuates vascular smooth muscle contraction through inhibiting Ca2+ influx in the rabbit thoracic aorta | J Biomed Biotechnol. | 2010 |
| 25 | 周壽紅 | Paraoxon down regulates ATP-binding cassette transporter A1 expression and decreases cholesterol efflux through cyclic AMP signaling pathway in RAW 264.7 macrophage-derived foam cells | Prog Biochem Biophys. | 2010 |
| 26 | 尹蔚蘭/ 唐小卿* | Hydrogen sulfide inhibits MPP+-induced apoptosis in PC12 cells | Life Sciences | 2009 |
| 27 | 田紹文 | Rapid eye movement sleep deprivation does not affect fear memory reconsolidation in rats, | Neuroscience Letters | 2009 |
| 28 | 凌宏艷 | Changes in microRNA profile and effects of miR-320 ininsulin-resistant 3T3-L1 adipocytes | Clin Exp Pharmacol Physiol. | 2009 |
| 29 | 顧洪豐 | Effect of inhibition of toll like receptor 4 on the development of atherosclerosis in apolipoprotein E knockout (apoE-/-) mice | Prog Biochem Biophys. | 2009 |
| 30 | 顧洪豐 | Effects of chronic mild stress on the development of atherosclerosis and expression of toll-like receptor 4 signaling pathway in adolescent apolipoprotein E knockout mice. | J Biomed Biotechnol. | 2009 |
| 31 | 唐小卿 | Effect of hydrogen sulphide on beta-amyloid-induced damage in PC12 cells. | Clin Exp Pharmacol Physiol. | 2008 |
| 32 | 顧朝亮/ 田紹文* | Chronic morphine selectively impairs cued fear extinction in rats: Implications for anxiety disorders associated with opiate use. | Neuropsychopharmacology | 2008 |
| 33 | 田紹文 | Prior chronic nicotine impairs cued fear extinction but enhances contextual fear conditioning in rats | Neuroscience | 2008 |
| 34 | 凌宏艷/ 胡 弼* | Effects of rosiglitazone on the proliferation of vascular smooth muscle cell induced by high glucose | Cardiovasc Drugs Ther | 2008 |
| 35 | 顧洪豐 | Effects of (-)-epigallocatechin-3-gallate on the development of atherosclerosis and toll-like receptor 4-nuclear factor kappa B signaling pathways in apoE-/- mice. | Cell Biology International | 2008 |
