主要經歷:
Ph.D.博士學位 專業: 有機化學; 研究方向: 不對稱催化 導師:馮小明教授
B.S.學士學位 專業: 套用化學 導師:馮小明教授
研究和工作經歷:
2014年9月 – 2015年4月: 研究助理教授 美國紐約州立大學水牛城分校 合作導師: Dr. Qing Lin
2009年8月 – 2014年8月: 生物化學研究助理,博士後研究助理,美國紐約州立大學水牛合作導師: Dr. Qing Lin
要研究方向
化學生物學
綠色有機合成化學
生物有機化學
主要工作業績
2008 年寶鋼教育獎,寶鋼優秀學生特等獎
2008-2009 四川大學創新人才一等獎
2007-2008 四川大學創新人才一等獎
2007-2008 四川大學優秀博士二等獎學金
2004-2005年四川大學優秀碩士研究生二等獎學金
2002年四川大學第四屆學生科技節動畫設計二等獎獎
代表性成果 (獲獎成果、專著、論文、專利)
1.以第一作者發表的研究論文: Zhipeng Yu and Qing Lin*, titled "Design of Spiro[2.3]hex-1-ene, a Genetically Encodable Double-Strained Alkene for Superfast Photoclick Chemistry" J. Am. Chem. Soc., 2014, 136, 4153–4156.2.以第一作者發表的研究論文: Zhipeng Yu, Tymish Y. Ohulchanskyy, Peng An, Paras N. Prasad, and Qing Lin*, titled "Fluorogenic, Two-Photon-Triggered Photoclick Chemistry in Live Mammalian Cells" J. Am. Chem. Soc., 2013, 135, 16766–16769.
3.以第一作者發表的研究論文: Zhipeng Yu, Yanchao Pan, Zhiyong Wang, Jiangyun Wang,* Qing Lin*, titled "Genetically Encoded Cyclopropene Directs Rapid, Photoclick-Chemistry-Mediated Protein Labeling in Mammalian Cells" Angew. Chem. Int. Ed. 2012, 51, 10600-10604.
4.以第一作者發表的研究論文: Zhipeng Yu, Lok Yin Ho, and Qing Lin*, titled "Rapid, Photoactivatable Turn-On Fluorescent Probes Based on an Intramolecular Photo click Reaction" J. Am. Chem. Soc., 2011, 133, 11912–11915.
5.以第一作者發表的研究論文: Zhipeng Yu, Lok Yin Ho, Zhiyong Wang, Qing Lin*, titled "Discovery of new photoactivatable diaryltetrazoles for photoclick chemistry via ‘scaffold hopping’" Bioorg. Med. Chem. Lett., 2011, 21, 5033-5036.
6.以第一作者發表的研究論文: Zhipeng Yu, Reyna K. V. Lim, Qing Lin*, titled "Synthesis of Macrocyclic Tetrazoles for Rapid Photoinduced Bioorthogonal 1,3-Dipolar Cycloaddition Reactions" Chem. Eur. J.2010, 16, 13325-13329
7.以合作作者發表的研究論文: Peng An, Zhipeng Yu and Qing Lin*, titled "Design of oligothiophene-based tetrazoles for laser-triggered photoclick chemistry in living cells" Chem. Commun., 2013,49, 9920-9922.
8.以合作作者發表的研究論文: Peng An, Zhipeng Yu and Qing Lin*, titled "Design and Synthesis of Laser-Activatable Tetrazoles for a Fast and Fluorogenic Red-Emitting 1,3-Dipolar Cycloaddition Reaction" Org. Lett., 2013, 15, 5496–5499.
9.以合作作者發表的研究論文: Jiangyun Wang, Wei Zhang, Wenjiao Song, Yizhong Wang, Zhipeng Yu, Jiasong Li, Minhao Wu, Lin Wang, Jianye Zang, and Qing Lin*, titled "A Biosynthetic Route to Photoclick Chemistry on Proteins" J. Am. Chem. Soc., 2010, 132, 14812–14818.
10.以合作作者發表的研究論文: Wenjiao Song, Yizhong Wang, Zhipeng Yu, Claudia I. Rivera Vera, Jun Qu, and Qing Lin*, titled "A Metabolic Alkene Reporter for Spatiotemporally Controlled Imaging of Newly Synthesized Proteins in Mammalian Cells" ACS Chem. Biol., 2010, 5, 875–885 (Cover Article)
11.以合作作者發表的研究論文: Wenjiao Song, Zhipeng Yu, Michael M. Madden and Qing Lin*, titled "A bioorthogonal chemistry strategy for probing protein lipidation in live cells" Mol. BioSyst., 2010, 6, 1576-1578.
12.以第一作者發表的研究論文: Zhipeng Yu, Xiaohua Liu, Lin Zhou, Lili Lin, Xiaoming Feng*, titled "Bifunctional Guanidine via an Amino Amide Skeleton for Asymmetric Michael Reactions of β-Ketoesters with Nitroolefins: A Concise Synthesis of Bicyclic β-Amino Acids" Angew. Chem. Int. Ed. 2009, 48, 5195-5198.
13.以合作作者發表的研究論文: Shao-Liang Zheng, Yizhong Wang, Zhipeng Yu, Qing Lin*, and Philip Coppens*, titled "Direct Observation of a Photoinduced Nonstabilized Nitrile Imine Structure in the Solid State" J. Am. Chem. Soc. 2009, 131, 18036-18037.
14.以第一作者發表的研究論文: Zhipeng Yu, Xiaohua Liu, Zhenhua Dong, Mingsheng Xie, and Xiaoming Feng*, titled "An N,N’-Dioxide/In(OTf)3 Catalyst for the Asymmetric Hetero-Diels-Alder Reaction Between Danishefsky’s Dienes and Aldehydes: Application in the Total Synthesis of Triketide". Angew. Chem. Int. Ed. 2008, 47, 1308-1311.
15.以合作作者發表的研究論文: Bo Gao, Zhipeng Yu, Zhengyan Fu and Xiaoming Feng*, titled "A Convenient and Versatile Approach to 2,3-dihydro-4H-pyran-4-ones via Tandem Aldol Reaction-conjugate Addition", Tetrahedron Letters 2006, 47, 1537-1539.
16.以合作作者發表的研究論文: Bo Gao, Zhengyan Fu, Zhipeng Yu, Lan Yu, Yaozong Huang and Xiaoming Feng*, titled "Highly enantioselective hetero-Diels–Alder reaction between trans-1-methoxy-2-methyl-3-trimethyl-siloxybuta-1,3-diene and aldehydes catalyzed by (R)- BINOL-Ti(IV) complex", Tetrahedron 2005, 61, 5822-5830.
17.以合作作者發表的研究論文: Ke Cheng, Baiqing Zeng, Zhipeng Yu, Bo Gao, Xiaoming Feng*, titled "A Mild and Efficient Synthesis of 2,5-disubstituted 2,3-Dihydro-4-pyridones Catalyzed by Yb(OTf)3", Synlett. 2005, 1018-1020.
18.以合作作者發表的研究論文: Zhengyan Fu, Bo Gao, Zhipeng Yu, Lan Yu, Yaozhong Huang, Xiaoming Feng,* Guolin Zhang,* titled "An Efficient and Enantioselective Approach to 2,5-Disubstituted Dihyropyrones", Synlett. 2004, 1772-1775.