人物生平
主要研究領域是分子植物—病原微生物相互作用、植物病原微生物基因組學、水稻分子生物學。以通訊作者發表SCI 論文20多篇,其中SCI 影響因子10以上的論文1篇,發表於國際基因組學最高專業雜誌Genome Research上並獲得高度評價;論文SCI他人引用300次以上。已5次受邀在國際學術大會上作報告,並為6種國際專業雜誌審稿。已申請專利5項,獲得授權3項。先後承擔科技部“973”項目子課題2項、“863”項目1項、科技攻關項目1項;國家自然科學基金4項(其中面上項目3項,海外青年合作基金1項);中國科學院“創新工程”項目2項;農業部《轉基因生物新品種培育科技重大專項》1項。
人物履歷
1983年7月:畢業於原華南熱帶農業大學(現合併為新海南大學),獲學士學位。
1983年7月至1992年6月:華南熱帶作物研究院(現為中國熱帶農業研究院)任研究實習員、助理研究員。
1984年9月至1985年10月:國際熱帶農業中心(CIAT)進修。
1992年7月至1993年6月:澳大利亞昆士蘭大學植物系研究生,獲研究生文憑。
1993年7月至1996年8月:澳大利亞昆士蘭大學植物系博士研究生,獲博士學位。
1996年9月至2000年5月:新加坡國立大學分子農業生物學院Research Fellow(博士後)。
2000年5月至2010年8月:入選中國科學院“百人計畫”,任中國科學院微生物所植物基因組學國家重點實驗室研究員、博士生導師。
2004年5月起:任清華大學深圳研究生院生命科學學部教授、博士生導師。從事水稻分子生物學和植物病原微生物分子遺傳學研究。
2010年9月起:任海南大學 “作物遺傳育種”國家重點學科責任教授、海南省熱帶生物資源可持續利用重點實驗室(省部共建國家重點實驗室培育基地)主任、博士生導師。
2011年6月-2014年12月:任海南大學農學院院長。
作品成就
研究方向
1.植物-病原微生物相互作用的分子機理
2.水稻廣譜抗病的分子機理及廣譜抗病種質創製
3.熱帶植物病害及其防控
社會學術兼職
1.《植物病理學報》副主編(2001-2010年)。
2.中國熱帶農業科學院“熱帶作物栽培生理農業部重點實驗室”學術委員會主任(2001起)。
發表論文
1.Xiaoyu LI, Xiuxiu HAN, Zhiqiang LIU, Chaozu HE(2013). The function and properties of the transcriptional regulator COS1 in Magnaporthe oryzae. fungal biology 117:239-249(通訊作者)2.Daqing Mao, Jun Tao, Chunxia Li, Chao Luo, Linlin Zheng and Chaozu He (2012) Light signalling mediated by Per-ARNT-Sim domain-containing proteins in Xanthomonas campestris pv. campestris. FEMS Microbiology Letters 326:31-39(通訊作者)
3Feng Feng Fan Yang, Wei Rong, Xiaogang Wu, She Chen, Chaozu He and Jian-Min Zhou (2012) A Xanthomonas uridine 5’-monophosphate transferase inhibits plant immune kinases. Nature 485: 114-118(通訊作者)
4. Yan Zhang & Feng Feng and Chaozu He (2012) Downregulation of OsPK1 Contributes to Oxidative Stress and the Variations in ABA/GA Balance in Rice Plant Mol Biol Rep 30:1006–1013(通訊作者)
5.Yan Zhang, Wenkai Xiao, ijuan Luo, inhuan Pang, ei Rong, Chaozu He(2012). Downregulation of OsPK1, a cytosolic pyruvate kinase, by T-DNA insertion causes dwarfism and panicle enclosure in rice. Planta. 235:25-38(通訊作者)
6.Daqing Mao,Jun Tao,Chunxia Li ,Chao Luo,Linlin Zheng,Chaozu He(2012) Identification of novel oxygen sensors using a combined approach in Xanthomonas campestris pv. Campestris. Ann Microbiol, 62:957–964
7.Chunxia Li, Jun Tao, Daqing Mao, Chaozu He(2011). A Novel Manganese Efflux System, YebN, Is Required for Virulence by Xanthomonas oryzae pv. oryzae. PLoS One 6: e21983. doi:10.1371/journal.pone.0021983(通訊作者)
8.Daqing Mao, Jun Tao, Chunxia Li, Chao Luo, Linlin Zhengand Chaozu He(2011) A novel one-component system, XvgA involved in regulation of bacterial growth and virulence of Xanthomonas campestris pv. Campestris, 5(25): 4433-4441(通訊作者)
9.Zhihui Xia, Huimin Xu , Jinling Zhai, Dejun Li, Hongli Luo, Chaozu He, Xi Huang(2011). RNA-Seq analysis and de novo transcriptome assembly of Hevea brasiliensis. Plant Molecular Biology 77:299-308(通訊作者)
10. Wei Rong, Feng Feng, Jian-Min Zhou and Chaozu He (2010) Effector-triggered innate immunity contributes Arabidopsis resistance to Xanthomonas campestris. Molecular Plant Pathology 11: 783-793. (通訊作者)
11. Jun Tao and Chaozu He (2010) Response regulator,VemR, positively regulates thevirulence and adaptation of Xanthomonas campestris pv. campestris. FEMS Microbiology Letters 304: 20–28. (通訊作者)
12. Zhuangzhi Zhou, Guihua Li, Chunhua Lin and Chaozu He (2009) Conidiophore Stalk-less1 Encodes a Putative Zinc-Finger Protein Involved in the Early Stage of Conidiation and Mycelial Infection in Magnaporthe oryzae. Molecular Plant-Microbe Interactions 22: 402–410. (通訊作者)
13. Wei Qian, Zhongji Han, Jun Tao and Chaozu He (2008) Genome-Scale Mutagenesis and Phenotypic Characterization of Two-Component Signal Transduction Systems in Xanthomonas campestris pv. campestris ATCC 33913. Molecular Plant-Microbe Interactions 21:1128-1138. (通訊作者)
14. Dongmei Yu, Kosala Ranathunge, Huasun Huang, Zhongyou Pei, Rochus Franke, Lukas Schreiber and Chaozu He (2008) Wax Crystal-Sparse Leaf1 encodes a β–ketoacyl CoA synthase involved in biosynthesis of cuticular waxes on rice leaf. Planta 228: 675–685. (通訊作者)
15. Chao Ge and Chaozu He (2008) Regulation of the Type II secretion structural gene xpsE in Xanthomonas campestris pathovar campestris by the global transcription regulator Clp. Current Microbiology 56:122-127. (通訊作者)
16. Lifeng Wang, Wei Rong and Chaozu He (2008) Two Xanthomonas extracellular polygalacturonases, PghAxc and PghBxc, are regulated by Type III secretion regulators HrpX and HrpG and are required for virulence. Molecular Plant-Microbe Interactions 21:555-563.(通訊作者)
17. Wei Qian, Zhong-Ji Han and Chaozu He (2008) Two-Component Signal Transduction Systems of Xanthomonas spp.: A Lesson from Genomics. Molecular Plant-Microbe Interactions 21:151-161.(通訊作者)
18. Hong, W.-F.; He, C.-Z.; Wang, L.-J; Wang, D.-J.; Joseph, L. M.; Jantasuriyarat, C.; Dai, L.-Y. and Wang G.-L. (2007). BWMK1 Responds to Multiple Environmental Stresses and Plant Hormones. Journal of Integrative Plant Biology 49:843-851
19. Hu, J.; Zhang, Y.; Qian, W. and Chaozu He (2007). Avirulence gene and insertion element based RFLP as well as RAPD markers reveal high levels of genomic polymorphism in the rice pathogen Xanthomonas oryzae pv. oryzae. Systematic and Applied Microbiology. 30:587–600
20. Lifeng Wang, Xiaoyan Tang and Chaozu He (2007). The bifunctional effector AvrXccC of Xanthomonas campestris pv. campestris requires plasmamembrane-anchoring for host recognition. Molecular Plant Pathology 8: 491-501.(通訊作者)
21. Chunxiao Xu and Chaozu He (2007). The rice OsLOL2 gene encodes a zinc finger protein involved in development and disease resistance. Molecular Genetics and Genomics 278: 85-94(通訊作者)。
22. Jun Hu, Wei Qian and Chaozu He (2007). The Xanthomonas oryzae pv. oryzae eglXoB endoglucanase gene is required for virulence to rice. FEMS Microbiology Letters269: 273–279(通訊作者)。
23. Guihua Li, Zhuangzhi Zhou, Guifu Liu, Fucong Zheng and Chaozu He (2007) Characterization of T-DNA insertion patterns in the genome of rice blast fungus Magnaporthe oryzae. Current Genetics 51: 233-243(通訊作者)。
24. Wei Qian, Yantao Jia, Shuang-Xi Ren, Yong-Qiang He Jia-Xun Feng, Ling-Feng Lu, Qihong Sun, Ge Ying, Dong-Jie Tang, Hua Tang, Wei Wu, Pei Hao, Lifeng Wang, Bo-Le Jiang, Shenyan Zeng, Wen-Yi Gu, Gang Lu, Li Rong, Yingchuan Tian, Zhijian Yao, Gang Fu, Baoshan Chen, Rongxiang Fang, Boqin Qiang, Zhu Chen, Guo-Ping Zhao, Ji-Liang Tang & Chaozu He (2005). Comparative and Functional Genomic Analyses for the Pathogenicity of Phytopathogen Xanthomonas campestris pv. campestris. Genome Research15: 757-767, (通訊作者)。
25. Lijuan Wang, Zhongyou Pei, Yingchuan Tian and Chaozu He (2005)OsLSD1, a Rice Zinc Finger Protein, Regulates Programmed Cell Death and Callus Differentiation. Molecular Plant Microbe Interactions 18: 375-384(通訊作者)
26. Guifu Liu, Lijuan Wang, Zhuangzhi Zhou, Hei Leung, Guo-liang Wang and Chaozu He (2004). A rice lesion mimic gene, Spl1, is physically mapped and delimitated in a 70 kb segment of rice chromosome 12. Molecular Genetics and Genomics, 272: 108-115. (通訊作者)
27. Qihong Sun, Jun Hu, Guixiu Huang, Chao Ge, Rongxiang Fang and Chaozu He (2005). The type II secretion pathway structural gene xpsE is required for xylanase- and cellulase- secretion and virulence in Xanthomonas oryzae pv. oryzae. Plant Pathology, 54: 15-21. (通訊作者)
28. Lian-Hui Wang, Yawen He, Yunfeng Gao, Ji En Wu, Yi-Hu Dong, Chaozu He, Su Xing Wang, Li-Xing Weng, Jin-Ling Xu, Leng Tay, Rong Xiang Fang, Lian-Hui Zhang (2004). A bacterial cell-cell communication signal with cross-kingdom structural analogues. Molecular Microbiology 51:903-912.
29. Youbao Sha, Shutian Li, Zhongyou Pei, Lijuan Luo, Yingchuan Tian and Chaozu He (2004). Generation and flanking sequence analysis of a rice T-DNA tagged population. Theoretical and Applied Genetics (TAG). 108: 306-314(通訊作者)
30. Qihong Sun, Wei Wu, Wei Qian, Jun Hu, Rongxiang Fang and Chaozu He (2003). High-quality mutant libraries of Xanthomonas oryzae pv. oryzae and X. campestris pv. campestris generated by an efficient transposon mutagenesis system. FEMS Microbiology Letters 226:145-150. (通訊作者)
31.Wang G.L., He C.Z., Wu C.J., Yin Z.C., Baraoidan M., Zeng L.R., Ronald P.C., Khush G.S. and Leung H. (2001) Genetic Dissection of Disease Resistance Pathways in Rice. Advances in Rice Blast Research. eds: M.H. Lebrun, J.L. Notteghem, N.J. Talbot and D. Tharreau. Kluwer Publisher, pp 63-72.
32.Chaozu He, Steven H. T. Fong , Daichang Yang and Guo-Liang Wang (1999).BWMK1, a novel MAP kinase induced by fungal infection and mechanical wounding in rice. Molecular Plant-Microbe Interactions. 12:1064-1073.
33.He, C., Rusu, A. G., Poplawski A. M., Irwin, J.A.G. and Manners, J.M. (1998). Transfer of a supernumery chromosome between vegetatively incompatible biotypes of the fungus Colletotrichum gloeosporioides. Genetics 150: 1459-1466.
34.Manners, J.M., He, C. (1997) Molecular approaches to studies of Colletotrichum gloeosporioidescausing anthracnose of Stylosanthes in Australia. Tropical Grassland, 31: 435-444. (review paper)
35.Poplawski A. M., He, C., Irwin, J.A.G. and Manners, J.M. (1997). Transfer of autonomously replicating vector between vegetatively incompatible biotypes of Colletotrichum gloeosporioides. Current Genetics, 32: 66-72.
36.He, C., Nourse, J.P., Kelemu, S., Irwin, J.A.G. and Manners, J.M. (1996) CgT1: A non-LTR retrotransposon with restricted distribution in the fungal phytopathogen Colletotrichum gloeosporioides. Molecular and General Genetics. 252: 320-331.
37.Masel AM*, He C.*, Poplawski AM, Irwin JAG, Manners JM (1996) Molecular evidence for chromosome transfer between biotypes of Colletotrichum gloeosporioides. Molecular Plant-Microbe Interactions, 9: 339-348 (*並列第一作者)
38.He C, Masel AM, Irwin JAG, Kelemu S, Manners JM (1995). Relationship of chromosome-specific dispensable DNA sequences in diverse isolates Colletotrichum gloeosporioides. Mycological Research 99: 1325-1333.