人物經歷
1997.9-2001.7 吉林大學化學學院高分子材料與工程工學學士學位;
2001.9-2006.7 吉林大學化學學院高分子化學與物理 理學博士學位;
2004.4-2005.3 比利時魯汶大學(University of Leuven) 交換博士生 (導師: Wim Dehaen 教授,Mario Smet 教授);
2006.8-2008.7 荷蘭屯特大學(University of Twente)MESA+納米技術研究所 博士後(合作導師:David Reinhoudt教授,Jurriaan Huskens 教授);
2008.7-2009.12 清華大學化學系 講師;
2009.12-2014.12 清華大學化學系 副教授;
2014.12至今 清華大學化學系 教授。
主要貢獻
1. Cao, W.; Gu, Y.; Li, T.; Xu, H.*: Ultra-sensitive ROS-responsive tellurium-containing polymers. Chem. Commun., 2015, Just Accepted.
2. Fang, R.; Xu, H.*; Cao, W.; Yang, L.; Zhang, X.*: Reactive Oxygen Species (ROS)-responsive Tellurium-containing Hyperbranched Polymer. Polym. Chem., 2015, DOI: 10.1039/C5PY00050E.
3. Ren, H.; Huang, Z.; Yang, H.; Xu, H.; Zhang, X.*.: Controlling the Reactivity of the Se-Se Bond by the Supramolecular Chemistry of Cucurbituril. ChemPhysChem, 2015, 16, 523.
4. Liu, W.; Wang, J.; Yu, Y.; Chang, Y.; Tang, N.; Qu, H.; Wang, Y.; Pang, W.; Zhang, H.; Zhang, D.; Xu, H.; Duan, X.*.: Tuning the Resonant Frequency of Resonators Using Molecular Surface Self-assembly Approach. ACS Appl. Mat. Interfaces, 2015, 7, 950.
5. Cao, W.; Wang L.; Xu H.*: Coordination Responsive Tellurium-containing Multilayer Film for Controlled Delivery. Chem. Commun., 2015, 51, 5520.
6. Huang, X.; Fang, R.; Wang, D.; Wang, J.; Xu, H.*; Wang, Y.*; Zhang, X.: Tuning Polymeric Amphiphilicity via Se-N Interactions: towards One-step Double Emulsion for Highly Selective Enzyme Mimics. Small, 2015, Accepted.
7. Li, T.; Yi, Y.; Xu, H.*: Selenium-containing Coordinating Assemblies with Selective Anti-cancer Activity: the Control of Reactive Oxygen Species. Acta Chim. Sinica, 2014, 72, 1079.
8. Wang, L.; Cao, W.; Yi, Y.; Xu, H.*: Dual Redox Responsive Co-assemblies of Diselenide-containing Block Copolymers and Polymer Lipids. Langmuir, 2014, 30, 5628.
9. Ji, S.; Cao, W.; Yu, Y.; Xu, H.*: Dynamic Diselenide Bonds: Exchange Reaction Induced by Visible Light without Catalysis. Angew. Chem. Int. Ed., 2014, 53, 6781. ( Hot Paper )
10. Zeng, L.; Li, Y.; Li, T.; Cao, W.; Yi, Y.; Geng, W.; Sun, Z.*; Xu, H.*: Selenium-platinum Coordination Compounds as Novel Anticancer Drugs: Selectively Killing Cancer Cells via a ROS-mediated Apoptosis Route. Chem. Asian. J., 2014, 9, 2295.
11. Cao, W.; Gu, Y.; Meineck, M.; Li, T.; Xu, H.*: Tellurium-containing Polymer Micelles: Competitive-Ligand-Regulated Coordination Responsive Systems. J. Am. Chem. Soc., 2014, 136, 5132.
12. Ding, Y.; Yi, Y.; Xu, H.; Wang, Z.; Zhang, X.*: Redox-responsive Thermal Sensitivity Based on a Selenium-containing Small Molecule. Chem. Commun., 2014, 50, 2585.
13. Cao, W.; Gu, Y.; Meineck, M.; Xu, H.*: The Combination of Chemotherapy and Radiotherapy towards More Efficient Drug Delivery. Chem. Asian. J., 2014, 9, 48 (Invited Focus Review).
14. Ji, S.; Cao, W.; Xu, H.*: A ROS Eliminating Nanocomposite Film Fabricated from Diselenide-Containing Polymer Micelles. Part. Part. Syst. Charact., 2013, 30, 1034.
15. Miao, X.; Cao, W.; Zeng, W.; Wang, J.; Gao, J.; Yang, C.; Kong, D.*; Xu, H.*; Wang, L.; Yang, Z.*: Switchable Catalytic Activity: Selenium-containing Peptides with Redox Controllable Self-assembly Property. Angew. Chem. Int. Ed., 2013, 52, 7781.
16. Ren, H.; Wu, Y.; Li, Y.; Cao, W.; Sun, Z.*; Xu, H.*; Zhang, X.: Visible Light Induced Disruption of Diselenide-Containing LbL Films: Toward Combination of Chemotherapy and Photodynamic Therapy. Small, 2013, 9, 3981.
17. Yi, Y.; Xu, H.*; Wang, L.; Cao, W.; Zhang, X.*: A Novel Dynamic Covalent Bond of Se-N: Towards Controlled Self-Assembly and Disassembly. Chem. Eur. J., 2013, 19, 9506.
18. Cao, W.; Zhang, X.; Miao, X.; Yang, Z.*; Xu, H.*: Gamma-ray Responsive Supramolecular Hydrogel Based on Diselenide-containing Polymer and Peptide. Angew. Chem. Int. Ed., 2013, 52, 6233.
19. Xu, H.*; Cao, W.; Zhang, X.*: Selenium-containing Polymers: Promising Biomaterials for Controlled Release and Enzyme Mimics. Acc. Chem. Res., 2013, 46, 1647.
20. Xu, H.*; Chen, D.; Wang, S.; Zhou, Y.; Sun, J.; Zhang, W.; Zhang, X.*: Macromolecular Self-Assembly and Nanotechnology in China. Phil. Trans. R. Soc. A, 2013, 371, 20120305.
21. Huang, X.; Qian, Q.; Zhang, X.; Du, W.; Xu, H.; Wang, Y.*: Assembly of Carbon Nanotubes on Polymer Particles: Towards Rapid Shape Change by Near-Infrared Light. Part. Part. Syst. Charact., 2013, 30, 235.
22. Cao, W.; Xu, H.*: Selenium-containing Polymers: A New Type of Biomaterial. (in Chinese) Chemistry Online, 2013, 76, 291. (Invited for Young Chemists Award of Chinese Chemical Society)
23. Han, P.; Li, S.; Cao, W.; Li, Y.; Sun, Z.; Wang, Z.; Xu, H.*: Red Light Responsive Diselenide-containing Block Copolymer Micelles. J. Mater. Chem. B, 2013, 1, 740.
24. Cao, W.; Li, Y.; Yi, Y.; Ji, S.; Zeng, L.; Sun, Z.*; Xu, H.*: Coordination-Responsive Selenium-Containing Polymer Micelles for Controlled Drug Release. Chem. Sci., 2012, 3, 3403.
25. Yi, Y.; Fa, S.; Cao, W.; Zeng, L.; Wang, M.; Xu, H.*; Zhang, X.: Fabrication of Well-Defined Crystalline Azacalixarene Nanosheets Assisted by Se···N Non-Covalent Interaction. Chem. Commun., 2012, 48, 7495.
26. Tan, X.; Yu, Y.; Liu, K.; Xu, H.; Liu, D.; Wang, Z.; Zhang, X.*: Single-Molecule Force Spectroscopy of Selenium-Containing Amphiphilic Block Copolymer: Toward Disassembling the Polymer Micelles. Langmuir, 2012, 28, 9601.
27. Meng, F.; Xu, H.; Qi, Y.; Xu, K.; Song, X.; Niu, S.; Li, J.*: Preliminary Studies on X-Ray-sensitive Liposome. Chem. Res. Chinese Universities, 2012, 28, 319.
28. Wu, G.; Verwilst, P.; Xu, J.; Xu, H.; Wang, R.; Smet, M.; Dehaen, W.; Faul, C. F. J.; Wang, Z.; Zhang, X.*: Bolaamphiphiles Bearing Bipyridine as Mesogenic Core: Rational Exploitation of Molecular Architectures for Controlled Self-Assembly. Langmuir, 2012, 28, 5023.
29. Li, S.; Han, P.; Xu, H.*: Self-healing Polymeric Materials. (in Chinese) Progress in Chemistry, 2012, 24, 1346.
30. Fu, Y.; Chen, J.; Xu, H.*; Van Oosterwijck, C.; Zhang, X.; Dehaen, W.; Smet, M.*: Fully-branched Hyperbranched Polymers with Diselenide Core as Glutathione Peroxidase Mimics. Macromol. Rapid Commun., 2012, 33, 798. (Invited for Special Issue of “ Polymer Science: the Next Generation”)
31. Xu, H.*; Schönhoff, M.; Zhang, X.: Unconventional Layer-by-Layer Assembly: Surface Molecular Imprinting and Its Applications. Small, 2012, 8, 517.
32. Ren, H.; Wu, Y.; Ma, N.; Xu, H.*; Zhang, X.: Side-chain Selenium-Containing Amphiphilic Block Copolymers: Redox-Controlled Self-Assembly and Disassembly. Soft Matter, 2012, 8, 1460. (Top ten most-read Soft Matter articles in December, 2011)
33. Han, P.; Li, S.; Wang, C.; Xu, H.; Wang, Z.; Zhang, X.*; Thomas, J.; Smet, M.: UV-Responsive Polymeric Superamphiphile Based on a Complex of Malachite Green Derivative and a Double Hydrophilic Block Copolymer. Langmuir, 2011, 27, 14108.
34. Liu, Z.; Yi, Y.; Gauczinski, J.; Xu, H.; Schönhoff, M.*; Zhang, X.*: Surface Molecular Imprinted Layer-by-Layer Film Attached to a Porous Membrane for Selective Filtration. Langmuir, 2011, 27, 11806.
35. Ma, N.; Xu, H.*; An, L.; Li, J.; Sun, Z.; Zhang, X.*: Radiation-Sensitive Diselenide Block Copolymer Micellar Aggregates: Toward the Combination of Radiotherapy and Chemotherapy. Langmuir, 2011, 27, 5874.
36. Ding, Y.; Chen, S.; Xu, H.; Wang, Z.; Zhang, X.*: Reversible Dispersion of Single-Walled Carbon Nanotubes Based on a CO-Responsive Dispersant. Langmuir, 2010, 26, 16667.
37. Han, P.; Ma, N.; Ren, H.; Xu, H.*; Li, Z.; Wang, Z.*; Zhang, X.: Oxidation-Responsive Micelles Based on a Selenium-Containing Polymeric Superamphiphile. Langmuir, 2010, 26, 14414.
38. Ma, N.; Li, Y.; Ren, H.; Xu, H.*; Li, Z.; Zhang, X.*: Selenium-containing Block Copolymers and Their Oxidation-responsive Aggregates. Polym. Chem., 2010, 1, 1609. (Front cover page)
39. Wang, Y.; Han, P.; Wu, G.; Xu, H.; Wang, Z.; Zhang, X.*: Selectively Erasable Multilayer Thin Film by Photoinduced Disassembly. Langmuir, 2010, 26, 9736.
40. Liu, Z.; Yi, Y.; Xu, H.*; Zhang, X.; Ngo, T. H.; Smet, M.: Cation Selective Microcontact Printing Based on Surface Molecular Imprinted Layer-by-Layer Film. Adv. Mater., 2010, 22, 2689. (Highlighted by NPG Asia Materials)
41. Gao, J.; Liu, Y.; Xu, H.*; Wang, Z.; Zhang, X.*: Biostructure-like Surfaces with Thermally Responsive Wettability Prepared by Temperature Induced Phase Separation Micro-molding. Langmuir, 2010, 26, 9673.
42. Wang, C.; Chen, Q.; Xu, H.; Wang, Z.; Zhang, X.*: Photo-responsive Supramolecular Amphiphiles for Controlled Self-assembly of Nanofibers and Vesicles. Adv. Mater. 2010, 22, 2553 .
43. Ma, N.; Li, Y.; Xu, H.*; Wang, Z.; Zhang, X.*: Dual Redox Responsive Assemblies Formed from Diselenide Block Copolymers. J. Am. Chem. Soc., 2010, 132, 442.
44. Xu, H.*; Huskens, J.*: Versatile Stamps in Microcontact Printing: Transferring Inks by Molecular Recognition and from Ink Reservoirs. Chem. Eur. J., 2010, 16, 2342.
45. Wang, Y.; Han, P.; Xu, H.; Wang, Z.; Zhang, X.*; Kabanov, A. V.:Photocontrolled Self-assembly and Disassembly of Block Ionomer Complex Vesicles: A Facile Approach toward Supramolecular Polymer Nanocontainers. Langmuir, 2010, 26, 709.
46. Wang, C.; Guo, Y.; Wang, Y.; Xu, H.; Wang, R.; Zhang, X.* : Supramolecular Amphiphiles Based on Water-soluble Charge Transfer Complex: Fabrication of Ultra-long Nanofiber with Tunable Straightness. Angew. Chem. Int. Ed., 2009, 48, 8962.
47. Wang, Y.; Zhang, M.; Moers, C.; Chen, S.; Xu, H.; Wang, Z.; Zhang, X.*; Li, Z.: Block Copolymer Aggregates with Photo-responsive Switches: Towards a Controllable Supramolecular Container. Polymer, 2009, 50, 4821.
48. Wang, C.; Guo, Y.; Wang, Y.; Xu, H.; Zhang, X.*: Redox Responsive Supramolecular Amphiphiles Based on Reversible Charge Transfer Interactions. Chem. Commun., 2009, 5380.
49. Xu, H.*; Gomez-Casado, A.; Liu, Z.; Reinhoudt, D. N.; Lammertink, R. G. H.*; Huskens, J.*: Porous Multilayer-Coated PDMS Stamps for Protein Printing. Langmuir, 2009, 25, 13972.
50. Wan, P.; Wang, Y.; Jiang, Y.; Xu, H.; Zhang, X.*: Fabrication of Reactivated Biointerface for Dual-Controlled Reversible Immobilization of Cytochrome c. Adv. Mater., 2009, 21, 4362.
51. Wu, C.; Xu, H.; Otto, C.; Reinhoudt, D. N.; Lammertink, R. G. H.; Huskens, J.; Subramaniam, V.*; Velders, A. H.*: Porous Multilayer-Coated AFM Tips for Dip-Pen Nanolithography of Proteins. J. Am. Chem. Soc., 2009, 131, 7526.
52. Zhang, Y.; Yu, Y.; Jiang, Z.; Xu, H.; Wang, Z.; Zhang, X.*; Oda, M.; Ishizuka, T.; Jiang, D.*; Chi, L.; Fuchs, H.: Single-Molecule Study on Intermolecular Interaction between C60 and Porphyrin Derivatives: Toward Understanding the Strength of the Multivalency. Langmuir, 2009, 25, 6627.
53. Jiang, Y.; Wan, P.; Xu, H.; Wang, Z.; Zhang, X.*; Smet, M.: Facile Reversible UV-Controlled and Fast Transition from Emulsion to Gel by Using a Photoresponsive Polymer with a Malachite Green Group. Langmuir, 2009, 25, 10134.
54. Wang, Y.; Xu, H.; Zhang, X.*: Tuning the Amphiphilicity of Building Blocks: Controlled Self-assembly and Disassembly for Functional Supramolecular Materials. Adv. Mater., 2009, 21, 2849.
55. Gao, J.; Liu, Y.; Xu, H.*; Wang, Z.; Zhang, X.*: Mimicking Biological Structured Surfaces by Phase Separation Micromolding. Langmuir, 2009, 25, 4365.
56. Xu, H.; Ling, X.; van Bennekom, J.; Duan, X.; Ludden, M. J. W.; Reindoudt, D. N.; Wessling, M.; Lammertink, R. G. H.*; Huskens, J.*: Microcontact Printing of Dendrimers, Proteins, and Nanoparticles by Porous Stamps. J. Am. Chem. Soc., 2009, 131, 797.
57. Wang, C.; Yin, S.; Chen, S.; Xu, H.; Wang, Z.; Zhang, X.*: Controlled Self-Assembly Manipulated by Charge-Transfer Interactions: From Tubes to Vesicles. Angew. Chem. Int. Ed., 2008, 47, 9049.
58. Gao, J.; He, Y.; Xu, H.; Song, B.; Zhang, X.*; Wang, Z.; Wang, X.* : Azobenzene-containing Supramolecular Polymer Films for Laser-Induced Surface Relief Gratings. Chem. Mater. , 2007 , 19, 14.
59. Jiang, Y.; Wang, Z.; Xu, H.; Chen, H.; Zhang, X.*; Smet, M.; Dehaen, W.; Hirano, Y.; Ozaki, Y.: Investigation into pH-responsive Self-Assembled Monolayers of Acylated Anthranilate Terminated Alkane Thiol on a Gold Surface. Langmuir, 2006, 22, 3715.
60. Wang, Y.; Xu, H.; Ma, N.; Wang, Z.; Zhang, X.*; Liu, J.; Shen, J.: Block Copolymer Micelles as Matrixes for Incorporating Diselenide Compound: Water-soluble Glutathione Peroxidase Mimic Fine-tuned by Ionic Strength. Langmuir, 2006, 22, 5552.
61. Xu, H.; Wang, Y.; Wang, Z.*; Liu, J.; Smet, M.*; Dehaen, W.: Dendritic Tellurides Act as Antioxidant. Chinese Science Bulletin, 2006, 51, 2315.
62. Xu, H.; Gao, J.; Wang, Y.; Wang, Z.; Smet, M.*; Dehaen, W.; Zhang, X.*: Hyperbranched Polyselenides as Glutathione Peroxidase Mimics. Chem. Commun., 2006, 796.
63. Jiang, Y.; Wang, Z.; Yu, X.; Shi, F.; Xu, H.; Zhang, X.*: Self-Assembled Monolayers of Dendron Thiols for Electrodeposition of Gold Nanostructures: Toward Fabrication of Superhydrophobic/Superhydrophilic Surfaces and pH-Responsive Surfaces. Langmuir, 2005, 21, 1986.
64. Zhang, X.*; Xu, H.; Dong, Z.; Wang, Y.; Liu, J.*; Shen, J.: Highly Efficient Dendrimer-Based Mimic of Glutathione Peroxidase. J. Am. Chem. Soc., 2004, 126, 10556. (Highlighted by ACS Heart Cut)
65. Huo, F.; Xu, H.; Zhang, L.; Fu, Y.; Wang, Z.; Zhang, X.*: Hydrogen-bonding Based Multilayer Assemblies by Self-deposition of Dendrimer. Chem. Commun., 2003, 874.
獲獎記錄
2014年自然科學基金委傑出青年科學基金;
2011年中國化學會青年化學獎;
2011年教育部新世紀優秀人才支持計畫。