基本情況
教育與研究經歷
2011.12至今 武漢大學化學與分子科學學院副教授
2011.08-2011.10 香港浸會大學訪問研究學者
2009.12-2011.11 武漢大學化學與分子科學學院講師
2008.10-2009.11 加拿大舍布魯克大學博士後
2003.09-2008.06 武漢大學理學博士
2006.03-2008.01 香港浸會大學研究助理
2004.09-2005.08 香港浸會大學交流研究生
1999.09-2003.06 武漢大學理學學士
2002.10-2003.06 香港浸會大學交流生
主授課程
物理化學
物理化學實驗
化學生物學導論
物理化學前沿與進展
主要研究領域與項目
研究領域與興趣
①納米材料製備、套用及生物效應；②多功能分子探針
科研項目
①國家自然科學基金
②留學回國人員科研啟動基金
③湖北省自然科學基金
④973計畫（參加）
主要學術成果
Huan He, Dong-Wei Li, Li-Yun Yang, Li Fu, Xun-Jin Zhu, Wai-Kwok Wong, Feng-Lei Jiang*, Yi Liu*. A novel bifunctional mitochondriatargeted anticancer agent with high selectivity for cancer cells. Scientific Reports, 2015, 5, 13543.
Li Fu, Fang-Fang Wang, Tao Gao, Rong Huang, Huan He, Feng-Lei Jiang*, Yi Liu*. Highly efficient fluorescent BODIPY dyes for reaction-based sensing of fluoride ions. Sensors and Actuators B, 2015, 216, 558-562.
Zi-Qiang Xu, Jia-Yi Lan, Jian-Cheng Jin, Tian Gao, Ling-Li Pan, Feng-Lei Jiang*, Yi Liu*. Mechanistic studies on the reversible photophysical properties of carbon nanodots at different pH. Colloids and Surfaces B: Biointerfaces, 2015, 130, 207-214.
Lu Lai, Jian-Cheng Jin, Zi-Qiang Xu, Ping Mei, Feng-Lei Jiang*, Yi Liu*. Necrotic cell death induced by the protein-mediated intercellular uptake of CdTe quantum dots. Chemosphere, 2015, 135, 240-249.
Lu Lai, Jian-Cheng Jin, Zi-Qiang Xu, Yu-Shu Ge, Feng-Lei Jiang*, Yi Liu*. Spectroscopic and Microscopic Studies on the Mechanism of Mitochondrial Toxicity Induced by CdTe QDs Modified with Different Ligands. Journal of Membrane Biology, 2015, 248, 727-740.
Li Fu, Fang-Fang Tian, Lu Lai, Yi Liu, Pierre D. Harvey, Feng-Lei Jiang*. A ratiometric “two-in-one” fluorescent chemodosimeter for fluoride and hydrogen sulfide.Sensors and Actuators B, 2014, 193, 701-707.
Jie Mei, Li-Yun Yang, Lu Lai, Zi-Qiang Xu, Can Wang, Jie Zhao, Jian-Cheng Jin, Feng-Lei Jiang*, Yi Liu*. The interactions between CdSe quantum dots and yeast Saccharomyces cerevisiae: Adhesion of quantum dots to the cell surface and the protection effect of ZnS shell. Chemosphere, 2014, 112, 92-99.
Jie Zhao, Zhi-Qiang Zhou, Jian-Cheng Jin, Lian Yuan, Huan He, Feng-Lei Jiang*, Xiao-Gang Yang*, Jie Dai, Yi Liu. Mitochondrial dysfunction induced by different concentrations of gadolinium ion. Chemosphere, 2014, 100, 194-199.
Chang-Qing Xiao, Bo-Ya Feng, Yu-Shu Ge, Xiao-Yang Fan, Feng-Lei Jiang*, Geng-Fu Xiao, Yi Liu*. Comprehensive study of the interaction between a potential antiprion cationic porphyrin and human prion protein at different pH by using multiple spectroscopic methods. Journal of Pharmaceutical Sciences, 2013, 102, 1076-1085.
Lu Lai, Chen Lin, Chang-Qing Xiao, Zi-Qiang Xu, Xiao-Le Han, Li Fu, Dong-Wei Li, Ping Mei, Feng-Lei Jiang*, Qing-Lian Guo*, Yi Liu*. Adhesion of quantum dots-induced membrane damage of Escherichia coli. Journal of Colloid and Interface Science, 2013, 389, 61-70.
Zi-Qiang Xu, Lu Lai, Dong-Wei Li, Ran Li, Chen Xiang, Feng-Lei Jiang*, Shao-Fa Sun, and Yi Liu*. Toxicity of CdTe QDs with different sizes targeted to HSA investigated by two electrochemical methods. Molecular biology reports, 2013, 40, 1009-1019.
Jin-Qiang Tong, Fang-Fang Tian, Qing Li, Li-Li Li, Chen Xiang, Yi Liu*, Jie Dai and Feng-Lei Jiang*. Probing the adverse temperature dependence in the static fluorescence quenching of BSA induced by a novel anticancer hydrazone. Photochemical & Photobiological Sciences, 2012, 11, 1868-1879.
Jia-Han Li, Xiao-Rong Liu, Yue Zhang, Fang-Fang Tian, Guang-Yuan Zhao, Qiu-Li-Yang Yu, Feng-Lei Jiang* and Yi Liu*. Toxicity of nano zinc oxide to mitochondria. Toxicology Research, 2012, 1, 137-144.
Mei-Fang Zhang, Zi-Qiang Xu, Yu-Shu Ge, Feng-Lei Jiang*, and Yi Liu*. Binding of fullerol to human serum albumin: Spectroscopic and electrochemical approach. Journal of Photochemistry and Photobiology B, 2012, 108, 34-43.
Lu Lai, Chen Lin, Zi-Qiang Xu, Xiao-Le Han, Fang-Fang Tian, Ping Mei, Dong-Wei Li, Yu-Shu Ge, Feng-Lei Jiang*, Ye-Zhong Zhang, Yi Liu*. Spectroscopic studies on the interactions between CdTe quantum dots coated with different ligands and human serum albumin. Spectrochimica Acta Part A, 2012, 97, 366-376.
Yue Zhang, Zi-Qiang Xu, Xiao-Rong Liu, Zu-De Qi, Feng-Lei Jiang*, and Yi Liu. Conformation and Thermodynamic Properties of the Binding of Vitamin C to Human Serum Albumin. Journal of Solution Chemistry, 2012, 41, 351-366.
Qing-Lian Guo, Juan Zhang, Zi-Qiang Xu, Ran Li, Feng-Lei Jiang*, Qi Xiao*, and Yi Liu. Comparative study on the effects of two antifungal drugs against Candida albicans by microcalorimetry and transmission electron microscopy. Thermochimica Acta, 2012, 543, 82-87.
Li Fu, Feng-Lei Jiang*, Daniel Fortin, Pierre D. Harvey*, and Yi Liu*. A reaction-based chromogenic and fluorescent chemodosimeter for fluoride anions. Chemical Communications, 2011, 47, 5503-5505.
Chang-Qing Xiao, Feng-Lei Jiang*, Bo Zhou, Ran Li, and Yi Liu. Interaction between a cationic porphyrin and bovine serum albumin studied by surface plasmon resonance, fluorescence spectroscopy and cyclic voltammetry. Photochemical & Photobiological Sciences, 2011, 10, 1110-1117.
Feng-Lei Jiang, Daniel Fortin, and Pierre D. Harvey. Syntheses, characterization and photophysical properties of conjugated organometallic Zn (II) porphyrin-containing oligomers. Inorganic Chemistry, 2010, 49, 2614-2623.
Yue-sheng Li, Yu-Shu Ge, Yue Zhang, Ai-Qing Zhang, Shao-Fa Sun, Feng-Lei Jiang*, and Yi Liu. Interaction of coomassie brilliant blue G250 with human serum albumin: probing the binding mechanism and binding site by spectroscopic and molecular modeling methods. Journal of Molecular Structure, 2010, 968, 24-31.
Yue-Sheng Li, Yue Zhang, Ze-Zhong Chen, Ai-Qing Zhang, Hong-Wu Tang, Feng-Lei Jiang*, and Yi Liu. Microcalorimetric and microscopic studies on the inhibitory activities of methylene blue/TiO nanocomposites on Staphylococcus aureus and the mechanism of cell damage. Thermochimica Acta, 2010, 501, 8-12.
Feng-Lei Jiang, Chun-Ting Poon, Wai-Kwok Wong, Ho-Kee Koon, Nai-Ki Mak, Chun Yu Choi, Daniel W. J. Kwong, and Yi Liu. Amphiphilic bisporphyrin and its Yb(III) complex: improved cellular uptake and development of a bifunctional photodynamic therapeutic and near-infrared tumor imaging agent. ChemBioChem, 2008, 9, 1034-1039.
Feng-Lei Jiang, Wai-Kwok Wong, Xun-Jin Zhu, Gui-Jiang Zhou, Wai-Yeung Wong, Po-Lam Wu, Hoi-Lam Tam, Kok-Wai Cheah, Cheng Ye, and Yi Liu. Synthesis, characterization and photophysical properties of some heterobimetallic bisporphyrins of ytterbium and transition metals-Enhancement and lifetime extension of Yb emission via transition metal porphyrin sensitization. European Journal of Inorganic Chemistry, 2007, 2007, 3365-3374.
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