個人簡介
姓名：董旻岳
性別：男
籍貫：浙江奉化
所屬學科：婦產科學
最後學歷：博士
職稱：主任醫師
研究生導師：博導
研究方向：生殖醫學、圍產醫學
現任職務：院長辦公室主任
董旻岳，男，醫學博士，博士研究生導師。1985年畢業於浙江醫科大學醫學系，2000年－2001年在美國伊利諾依大學芝加哥分校（UIC）醫學院從事生殖生理學博士後研究。研究領域為生殖醫學和圍產醫學，主要研究方向為妊娠免疫耐受機制、生殖和妊娠相關疾病的免疫學病因與發病機制，近年特別關注滋養細胞功能與妊娠併發症關係以及妊娠併發症對子代影響及機制的研究。主持、承擔國家自然科學基金、973項目子課題等課題多項。發表學術論文百餘篇，主要論文均發表在SCI刊物，獲科技成果獎勵6項。
主要在研課題
1.Follistatin-like 3對滋養細胞與胚胎的影響以及在妊娠併發症中的作用。2013年國家自然科學基金（課題負責人）2.子宮內膜細胞脂肪酸結合蛋白4在胚胎著床中的作用與機制研究。2011年國家自然科學基金（課題負責人）
3.輔助生殖誘發胚胎源性疾病的風險評估和機制研究。2011年國家重大科學研究計畫（973）項目（學術骨幹）
4.Toll樣受體7、8介導的炎性反應通路在滋養細胞阻止B型肝炎病毒宮內傳播中的作用。2010年浙江省自然科學基金（課題負責人）
近五年成果獲獎
1. 提高出生人口質量的生殖技術創建、體系最佳化與臨床推廣套用：2010年國家科技進步二等獎；2. 阻斷出生缺陷、促進子代健康關鍵技術體系的創建與推廣套用：2010年浙江省科技進步一等獎；
近五年發表的代表性論文（*為通訊作者）
1. He J, Zhang AP, Fang M, Fang R, Ge JM, Jiang Y, Zhang H, HanC, Ye XQ, Yu DQ, Huang HF, Liu Y*, DongMY*. Methylation levels at IGF2 and GNAS DMRs in infants born to preeclampticpregnancies. BMC Genomics, 2013, 14:472.2. Zhou QY, Li J, Wang HZ, Han C, Tian T, Zhu QY, Huang HF,Dong MY*. Serum preadipocytefactor-1 is increased in fetuses of pregnancy complicated with severepreeclampsia. Clinica Chimica Acta, 2013, 424:212-215.
3. Guo J, Tian T, Lu DH, Xia GY, Wang HZ,Dong MY*.Alterations of maternal serum and placentalfollistatin-like 3 and myostatin in pre-eclampsia. J Obstet Gynecol Res, 2012Jul, 38( 7):988-996.
4. Hu DX, Tian T, Guo J, Wang HZ, Chen DQ,Dong MY*. Decreased maternal and placental concentrations offollistatin-like 3 ingestational diabetes. Clinica Chimica Acta, 2012, 413: 533-536.
5. Yin LJ, Zhang Y, Lv, PP, He WH, Wu YT, Liu AX, Ding GL,Dong MY,QuF, Xu CM, Zhu XM, Huang HF. Insufficient maintenance DNA methylation isassociated with abnormal embryonic development. BMC Med. 2012;10:26.
6. Liu FJ, Guo J, Tian T, Wang HZ, Dong FY, Huang HF,Dong MY*. Placental trophoblastsshifted Th1 ? Th2 balance toward Th2 and inhibited Th17 immunity atfetomaternal interface. APMIS, 2011, 119: 597–604.
7. Wang N, Wang, LY, Le F, Zhan QT, Zheng YM, Ding GL, Chen XJ,Sheng JZ,Dong MY,Huang HF,Jin F. Altered expression of Armet and Mrlp51 inthe oocyte, preimplantation embryo, and brain of mice following oocyte in vitromaturation but postnatal brain development and cognitive function are normal.Reproduction, 2011,142( 3):401-408.
8. Chen D, Xia G, XuP,Dong MY*. Peripartum serumleptin and soluble leptin receptor levels in women with gestational diabetes.Acta Obstet Gynecol Scand. 2010, 89(12): 1595- 1599.
9. Zhang K, He J,Dong MY*. Relationship betweenumbilical artery Doppler waveform analysis and perinatal prognosis in womenwith intrahepatic cholestasis of pregnancy. Int J Gynaecol Obstet. 2010;111(2):187-8.
10.Wang TT, Wu YT,Dong MY,Sheng JZ Leung PC,Huang HF. G546Apolymorphism of growth differentiation factor-9 contributes to the poor outcomeof ovarian stimulation in women with diminished ovarian reserve. FERTILITY ANDSTERILITY. 2010; 94(6): 2490-2492.
11.Liang ZX,Dong MY, Cheng Q, Chen DQ.Gestational diabetes mellitus screening based on the gene chip technique.Diabetes Res Clin Pract, 2010 Aug, 89(2):167-73.
12.Qu F, Wang FF, LuXE,Dong MY, Sheng JZ, Lv PP,Ding GL, Shi BW, Zhang D, Huang HF. Altered aquaporin expression in women withpolycystic ovary syndrome: hyperandrogenism in follicular fluid inhibitsaquaporin-9 ingranulosa cells through the phosphatidylinositol 3-kinase pathway. HUMANREPRODUCTION,JUN 2010, 25(6): 1441-1450
13.Ding GL, Chen XJ,Luo Q,Dong MY, Wang N, Huang HF.Attenuated oocyte fertilization and embryo development associated with alteredgrowth factor/signal transduction induced by endometriotic peritoneal fluid.FERTILITY AND STERILITY, MAY 2010, 93(8): 2538-2544
14.Wei J, Wang HM, Yang XF,Dong MY, Wang ZP. Altered gene profile of placenta from women with intrahepaticcholestasis of pregnancy. Arch Gynecol Obstet, 2010 May, 281( 5): 801-10
15.Lou H, Ding W,Dong MY, Zhu Y, Zhou C, Wang Z,Yang X, Yao Q,Li D, Miao M. The Presence of Hepatitis B Surface Antigen in the Ova ofPregnant Women and Its Relationship with Intra-uterine Infection by Hepatitis BVirus. J Int Med Res, 2010, 38(1): 214-9
16.Tang L, Zhang Y,Pan H, Luo Q, Zhu XM,Dong MY,Leung PCK, Sheng JZ, Huang HF. Involvement of cyclin B1 in progesterone-mediated cell growthinhibition, G2/M cell cycle arrest, and apoptosis in human endometrial cell.Reprod Biol Endocrinol, 2009, 7:
17.Shangguan XJ, Liu FJ, Wang HZ, He J,DongMY*.Alterations in serum adipocytefatty acid binding protein and retinol binding protein-4 in normal pregnancy and preeclampsia.Clinica Chimica Acta, 2009, 407: 58-61
18.Chen DQ, Wang HZ,Huang HF,Dong MY*. VascularEndothelial Growth Factor Attenuates Nω-Nitro-L-Arginine Methyl Ester-InducedPreeclampsia-Like Manifestations in Rats. Clinical and ExperimentalHypertension. 2008 Oct, 30(7): 606- 615.
19.Chen X, Qian X,Chen H,Dong M*. Serum levelsof nitric oxide metabolites during labour with or without combinedspinal-epidural analgesia. EUROPEAN JOURNAL OF ANAESTHESIOLOGY. 2008 Sep,25 (9): 708-713
20.Feng C, Wang LQ,Dong M, HuangHF. Needfor standardization and confirmation of STS deletions on the Y chromosome – Reply.FERTILITY AND STERILITY. 2008 Aug, 90 (2): 464-464
21.Feng C, Wang LQ,Dong M*, Huang HF. Assisted reproductive technology may increase clinicalmutation detection in male offspring. FERTILITY AND STERILITY, 2008 Jul, 90(1):92-96.
22.Huang H,Dong M*. The effect of trohphoblasts on T lymphocytes and the role of indoamine2,3-dioxigenase. Human Reproduction. 2007 Jul, 22 (Supl 1): 112-112 Meetingabstract O028.
23.Minyue Dong*,Guolian Ding, Jun Zhou, Hanzhi Wang,Yi Zhao, Hefeng Huang. The effect oftrohphoblasts on T lymphocytes: Possible regulatory effector molecules--Aproteomic analysis. Cellular Physiology and Biochemistry, 2008, 21:463-472.
24.Wensheng HU, Zhengping WANG，Hanzhi WANG, Hefeng HUANG andMinyue DONG*. Serum Visfatin Levels in Late Pregnancy and Preeclampsia. Acta ObstetGynecol Scand, 2008 April, 87(4): 413-418.
25.Dongxiao Hu, Zhengping Wang, Wuwen Zhang, Hanzhi Wang, andMinyue Dong*.Alteration of Peripheral CD4CD25Regulatory T Lymphocytes in Pregnancy and Preeclampsia. Acta Obstet GynecolScand, 2008, 87(2): 190-194.
26.Qingxia Meng, Huijuan Gao, Chengming Xu,MinyueDong, Xia Sheng, Jiangzhong Sheng,Hefeng Huang. Reduced Expression and Function of Aquaporin-3 in Mouse Metaphase II Oocytes Induced byControlled Ovarian Hyperstimulation Were Associated with Subsequent Lowfertility Rate. Cell Physiol and Biochem, 2008; 21: 123-128.
