人物履歷
2007畢業於中國科學技術大學獲得理學博士學位; 2007年至2011年於瑞士Ludwig腫瘤學研究所從事博士後研究。主要研究成果發表於PNAS,Blood和 J IMMUNOL等國際高水平雜誌。
獲得榮譽
獲2006年中科院院長優秀獎和2007年中華醫學會一等獎。
2018年9月30日,獲得第三屆北京市華僑華人“京華獎”。
研究領域
1) 腸道上皮內淋巴細胞功能及發育分化研究
2) 模式識別受體調節腸道黏膜穩態的機制研究
代表論著
1、 Jiang W, Sun R, Wei H, Tian Z. Toll-like receptor 3 ligand attenuates LPS-induced liver injury by down-regulation of toll-like receptor 4 expression on macrophages. Proc. Natl. Acad. Sci. USA (PNAS) 2005, 102(47): 17077–17082.
2、 Jiang W, Ferrero I, Laurenti E, Trumpp A, Macdonald HR. c-Myc controls the development of CD8αα TCRαβ intestinal intraepithelial lymphocytes from thymic precursors by regulating IL-15-dependent survival. Blood. 2010, 115(22):4431-8.
3、 Jiang W, Sun R, Zhou R, Wei H, Tian Z. TLR-9 activation aggravates concanavalin A-induced hepatitis via promoting accumulation and activation of liver CD4+ NKT cells. J Immunol. 2009,182(6):3768-74.
4、Fiorini E, Merck E, Wilson A, Ferrero I, Jiang W, Koch U, Auderset F, Laurenti E, Tacchini-Cottier F, Pierres M, Radtke F, Luther SA, Macdonald HR. Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies. J Immunol. 2009, 183(11):7212-22.
5、Mycko MP, Ferrero I, Wilson A, Jiang W, Bianchi T, Trumpp A, MacDonald HR. Selective requirement for c-Myc at an early stage of Vα14i NKT cell development. J Immunol. 2009, 182(8):4641-8.
6、Chen Y, Sun R, Jiang W, Wei H, Tian Z. Liver-specific HBsAg transgenic mice are over-sensitive to Poly (I:C)-induced liver injury in NK cell- and IFN-γ denpendent manner. J Hepatol. 2007, 47(2):183-90.