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人物經歷
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李月明[南開大學藥學院教授]李月明 （教授，博士生導師），南開大學藥學院任職，住天津市南開區八里台衛津路94號， 1988.9.-1991.6.天津南開大學化學系：博士學位 1985.9.-1988.7.天津南開大學化學系：碩士學位， 1981.9.-1985.7. 天津南開大學化學系：大學本科。
工作經歷
1. 2009年4月：南開大學藥學院教授，博士生導師。
2. 2008年6月：中山大學藥學院教授，博士生導師。
3. 2007年4月：天津市第五批特聘教授。
4. 2006年：取得中山大學藥學院兼職博士生導師資格。
5. 2005年：入選中國科學院“百人計畫”。
6. 1998.4.-2009:香港理工大學套用生物及化學科技學系：Research Associate （1998-2004）/ Research Fellow （2004-2009）。
7. 1996.12.-1998.4.: 德國哥廷根大學（University of Goettingen,Göttingen,Germany) 有機化學研究所：客座研究員(visiting scientist）。
8. 1995.10.-1996.12:印度國家化學實驗室（National Chemical Laboratory,Pune,India）：“第三世界科學院/印度政府CSIR”博士後。CSIR,Council of Scientific & Industrial Research，印度政府科學與工業研究委員會。該機構是世界上最大的公共基金支持的科學技術委員會之一。
9. 1993.12-1995.10.: 天津南開大學化學系副教授。
10. 1991.6-1993.12.: 天津南開大學化學系講師。
研究方向
不對稱催化方法學研究，不對稱有機合成反應研究，酶抑制劑的設計與合成（包括神經氨酸酶抑制劑、組蛋白去乙醯化酶抑制劑、乙醯膽鹼酯酶抑制劑、alpha-葡萄糖苷酶抑制劑、COX-Ⅱ抑制劑等），以DNA為靶點的小分子的化合物及其生物活性研究。
主要貢獻
出版著作
1.林國強陳耀全陳新滋李月明：《手性合成 — 不對稱反應及其套用》，科學出版社：北京，2000。ISBN: 7-03-008114-5，本書2002年獲教育部全國普通高校優秀教材二等獎。
2. Guo-Qiang Lin,Yue-Ming Li,Albert S. C. Chan: “Principles and Applications of Asymmetric Synthesis.” John Wiley & Sons,Inc.: New York,2001. ISBN: 0-471-40027-0。
3. 李月明 范青華 陳新滋：《不對稱有機反應 — 催化劑的回收與再利用》，化學工業出版社：北京，2003。ISBN 7-5025-4497-6。
4. 林國強 李月明 陳耀全 陳新滋：《手性合成 — 不對稱反應及其套用 （第二版）》，科學出版社：北京，2005。ISBN 7-03-014533-X，本書為中國科學院研究生教學用書。
5. 李月明 范青華 陳新滋：《不對稱有機反應》，化學工業出版社：北京，2005。ISBN 7-5025-6222-2。
6. 林國強 陳耀全 李月明 陳新滋：《手性合成 — 不對稱反應及其套用 (第三版)》，科學出版社：北京，2007。ISBN 978-7-03-019210-3，本書為中國科學院研究生教學叢書。
參編著作
1. Yue-Ming Li,Wing-Yiu Yu,and Albert S. C. Chan “Atropisomeric Biheteroaromatic Diphosphines” in Armin Börner Ed. “Phosphorus ligands in asymmetric catalysis” (p260-283）. Wiley-VCH,2008. ISBN 978-3-527-31476-2.
2. Yue-Ming Li,Ming Yan,and Albert S. C. Chan “Atropisomeric Partially Hydrogenated 1,1’-Binaphthyl Diphosphines” in Armin Börner Ed. “Phosphorus ligands in asymmetric catalysis” (p284-306）. Wiley-VCH,2008. ISBN 978-3-527-31476-2.
代表性論文（被引用780餘次，其中被他人引用670餘次）
1. Qing-Hua Fan,Yue-Ming Li*,Albert S. C. Chan* “Recoverable Catalysts for Asymmetric Organic Synthesis.” Chemical Reviews 2002,102⑽，3385-3465.
2. Qiu,Liqin; Kwong,Fuk Yee; Wu,Jing; Lam,Wai Har; Chan,Shusun; Yu,Wing-Yiu; Li,Yue-Ming; Guo,Rongwei; Zhou,Zhongyuan; Chan,Albert S. C. “New Class of Versatile Chiral-Bridged Atropisomeric Diphosphine Ligands: Remarkably Efficient Ligand Syntheses and Their Applications in Highly Enantioselective Hydrogenation Reactions.” Journal of the American Chemical Society 2006,128⒄，5955-5965.
3. Jin-Lin Zhou,Yu-Jing Lu,Tian-Miao Ou,Jun-Min Zhou,Zhi-Shu Huang,* Xiao-Feng Zhu,Cui-Juan Du,Xian-Zhang Bu,Lin Ma,Lian-Quan Gu,Yue-Ming Li,* and Albert Sun-Chi Chan “Synthesis and Evaluation of Quindoline Derivatives as G-Quadruplex Inducing and Stabilizing Ligands and Potential Inhibitors of Telomerase.” Journal of Medicinal Chemistry 2005,48（23），7315-7321.
4. Zhi-Shu Huang,* Hai-QiangWu,Zhi-Fang Duan,Bing-Fen Xie,Zong-Chao Liu,Gong-Kan Feng,Lian-Quan Gu*,Albert S.C. Chan,Yue-Ming Li* “Synthesis and cytotoxicity study of alkannin derivatives.” European Journal of Medicinal Chemistry 2004,39,755-764.
5. Qiong Shen,Quan Peng,Jialiang Shao,Xufeng Liu,Zhishu Huang,Xianzhang Pu,Lin Ma*,Yue-Ming Li*,Albert S.C. Chan,Lianquan Gu* “Synthesis and biological evaluation of functionalized coumarins as acetylcholinesterase inhibitors.” European Journal of Medicinal Chemistry 2005,40⑿，1307-1315.
6. Yue-Ming Li,Fuk-Yee Kwong,Wing-Yiu Yu,Albert S.C. Chan “Recent advances in developing new axially chiral phosphine ligands for asymmetric catalysis.” Coordination Chemistry Reviews 2007,251（17-20），2119-2144.
7. Jiwu Ruan,Gui Lu,Lijing Xu,Yue-Ming Li,Albert S. C. Chan “Catalytic Asymmetric Alkynylation and Arylation of Aldehydes by an H8-Binaphthyl-Based Amino Alcohol Ligand.” Advanced Synthesis & Catalysis 2008,350⑴，76-84.
8. Sheng-Ling Zhang,Zhi-Shu Huang,Yue-Ming Li,Albert S.C. Chan,Lian-Quan Gu “Synthesis of zwitterionic 4-hydroxy-2（1H)-quinolinone derivatives.” Tetrahedron 2008,64⒆，4403-4407.
9. Sau Hing Chan,Kim Hung Lam,Yue-Ming Li,Lijin Xu,Weijun Tang,Fuk Loi Lam,Wai Hung Lo,Wing Yiu Yu,Qinghua Fan and Albert S.C. Chan “Asymmetric hydrogenation of quinolines with recyclable and air-stable iridium catalyst systems.” Tetrahedron: Asymmetry 2007,18（22），2625-2631.
10. Liqin Qiu,Yue-Ming Li,Fuk Yee Kwong,Wing-Yiu Yu,Qing-Hua Fan,Albert S. C. Chan* “Highly Efficient Asymmetric Hydrogenation of a,b-Unsaturated Carboxylic Acids Catalyzed by Ruthenium（Ⅱ）-Dipyridylphosphine Complexes.” Advanced Synthesis & Catalysis 2007,349（4-5），517-520.
11. Gui Lu,Xingshu Li,Yue-Ming Li,Fuk Yee Kwong,Albert S. C. Chan “Highly Enantioselective Catalytic Alkynylation of Ketones - A Convenient Approach to Optically Active Propargylic Alcohols.” Advanced Synthesis & Catalysis 2006,348⒁，1926-1933.
12. Li-Xia Pei,Yue-Ming Li,Xian-Zhang Bu,Lian-Quan Gu and Albert S.C. Chan “One-pot synthesis of 5,6-dihydroxylated benzo[b]furan derivatives.” Tetrahedron Letters 2006,47⒂，2615-2618.
13. Gui Lu,Fuk Yee Kwong,Ji-Wu Ruan,Yue-Ming Li,Albert S. C. Chan “Highly Enantioselective Addition of In Situ Prepared Arylzinc to Aldehydes Catalyzed by a Series of Atropisomeric Binaphthyl-Derived Amino Alcohols.” Chemistry: A European Journal 2006,12⒂，4115-4120.
14. Fuk Yee Kwong,Yue Ming Li,Wai Har Lam,Liqin Qiu,Hang Wai Lee,Chi Hung Yeung,Kin Shing Chan,and Albert S. C. Chan “Rhodium-Catalyzed Asymmetric Aqueous Pauson–Khand-Type Reaction.” Chemistry: A European Journal 2005,11⒀，3872-3880.
15. Fuk Yee Kwong,Hang Wai Lee,Liqin Qiu,Wai Har Lam,Yue-Ming Li,Hoi Lun Kwong,Albert S. C. Chan “Rhodium-BisbenzodioxanPhos Complex-Catalyzed Homogeneous Enantioselective Pauson- Khand-Type Cyclization in Alcoholic Solvents.” Advanced Synthesis & Catalysis 2005,347,1750-1754.
16. Gui Lu,Yue-Ming Li,Xing-Shu Li,Albert S.C. Chan* “Synthesis and application of new chiral catalysts for asymmetric alkynylation reactions.” Coordination Chemistry Reviews 2005,249,1736–1744.
17. Lai-Lai Wang,Rong-Wei Guo,Yue-Ming Li,Albert S. C. Chan “Rhodium-catalyzed asymmetric hydroformylation of vinylarenes with novel chiral P,N-ligands derived from 1,2:5,6-di-O-cyclohexylidene-D-mannitol.” Tetrahedron: Asymmetry 2005,16,3198-3204.
18. Jian-Ying Qi,Yue-Ming Li,Zhong-Yuan Zhou,Chi-Ming Che,Chi-Hung Yeung*,and Albert S. C. Chan* “Novel Manganese Complex as an Efficient Catalyst for the Isobutyraldehyde Mediated Epoxidation of Cyclic Alkenes with Dioxygen.” Advanced Synthesis and Catalysis 2005,347⑴，45-49.
19. Wang,R. H.; Xu,L. J.; Ji,J. X.; Shi,Q.; Li,Y. M.; Zhou,Z. Y.; Hong,M. C.; Chan,A. S. C. “Metal-directed stereoselective syntheses of homochiral complexes of exo-bidentate binaphthol derivatives.” European Journal of Inorganic Chemistry 2005，⑷，751-758.
20. Sheng-Ling Zhang,Zhi-Shu Huang,Lin-Kun An,Xian-Zhang Bu,Lin Ma,Yue-Ming Li,Albert S. C. Chan,and Lian-Quan Gu “Synthesis of Zwitterionic 4-Hydroxycoumarin Derivatives through a Unique Reaction of 4-Hydroxycoumarins with p-Benzoquinone and Pyridine.” Organic Letters 2004,6（26），4853-4855.
21. Yi,B.; Fan,Q. H.; Deng,G. J.; Li,Y. M.; Qiu,L. Q.; Chan,A. S. C. “Novel chiral dendritic diphosphine ligands for Rh(I)-catalyzed asymmetric hydrogenation: Remarkable structural effects on catalytic properties.” Organic Letters 2004,6⑼，1361-1364.
22. Jia,X.; Li,X.; Xu,L. J.; Li,Y. M.; Shi,Q.; Au-Yeung,T. T. L.; Yip,C. W.; Yao,X. S.; Chan,A. S. C. “Titanium-catalyzed tandem sulfoxidation-kinetic resolution process: A convenient method for higher enantioselectivities and yields of chiral sulfoxide.” Advanced Synthesis & Catalysis 2004,346 ⑺，723-726.
23. Lailai Wang,Yue-Ming Li,Chiu-wing Yip,Liqin Qiu,Zhongyuan Zhou,and Albert S. C. Chan* “Synthesis of New Chiral Aryl Diphosphite Ligands Derived from Pyranoside Backbone of Monosacharides and Their Application in Copper-Catalyzed Asymmetric Conjugate Addition of Diethylzinc to Cyclic Enones.” Advanced Synthesis and Catalysis 2004,346,947-953.
24. Chen,X. H.; Guo,R. W.; Li,Y. M.; Chen,G.; Yeung,C. H.; Chan,A. S. C. “Application of phosphinous amide ligands in palladium complex-catalyzed asymmetric allylic alkylation: influence of steric effects on enantioselectivity.” Tetrahedron: Asymmetry 2004,15⑵，213-217.
25. Liang Liang,Ming Yan,Yue-Ming Li and Albert S. C. Chan “Highly enantioselective copper-catalyzed 1,4-conjugation addition of diethylzinc to cyclic enones and a,b-unsaturated lactones.” Tetrahedron: Asymmetry 2004,15,2575-2578.
26. Cheng-Chao Pai,Yue-Ming Li,Zhong-Yuan Zhou,Albert S. C. Chan* “Synthesis of New Chiral Diphosphine Ligand (BisbenzodioxanPhos) and its Application in Asymmetric Catalytic Hydrogenation.” Tetrahedron Letters 2002,43⒂，2789-2792.
27. Yi-Xin Chen,Li-Wei Yang,Yue-Ming Li,Zhong-Yuan Zhou,Kim-Hung Lam,Albert S. C. Chan,Hoi-Lun Kwong “Synthesis of a New Chiral Ligand,6,6'-Dihydroxy-5,5'- Biquinoline (BIQOL) and Its Applications in the Asymmetric Addition of Diethylzinc to Aldehydes.” Chirality 2000,12（5/6），510-513.
28. Ching-Wen Lin,Chi-Ching Lin,Yue-Ming Li and Albert S. C. Chan “A Highly efficient and stereospecific borane reduction of spiro[4.4] nonane-1,6-dione catalyzed by a chiral oxazaborolidine.” Tetrahedron Letters 2000,41（22），4425-4429
29. Renneberg, Bernd; Li, Yue-Ming; Laatsch, Hartmut; Fiebig, Heinz-Herbert “A short and efficient transformation of rhamnose into activated daunosamine, acosamine, ristosamine and epi-daunosamine derivatives, and synthesis of an anthracycline antibiotic acosaminyl--iso-rhodomycinone.” Carbohydrate Research 2000, 329(4), 861-872.
30. Bhatia, D., Li, Y.-M., Ganesh, K. N. “Steroid - DNA conjugates: Improved triplex formation with 5-amido-(7- deoxycholic acid)-dU incorporated oligonucleotides.” Bioorganic & Medicinal Chemistry Letters 1999, 9, 1789-1794.
31. Li Yue-Ming*, Yao Xiao-Jie, Feng Xiao, Wang Xue-Mei, Wang Ji-Tao “Asymmetric Aldol Condensation Reaction of Acetyl Ferrocene with Aromatic Aldehydes via Formation of beta-CD Inclusion Complexes.” J. Organomet. Chem. 1996, 509/2, 221.
獲獎記錄
1. 國家自然科學獎（二等獎，2005年。獲獎證書號碼：2005-Z-103-2-04-R05）。
2. 著作《手性合成 – 不對稱反應及其套用》獲教育部全國普通高等學校優秀教材二等獎（2002年）。
3. 1995年4月至7月參與國際奧林匹克化學競賽中國隊參賽隊員的培訓工作，並於同年7月作為中國代表團領隊參加第27屆國際奧林匹克化學競賽，所有中國隊參賽隊員都獲得金牌，中國隊並獲得團體總分第一。本人受中國化學會表彰。
4. 1993年國家教委霍英東教育基金會青年教師獎。
