李德昌[浙江大學副教授]

李德昌,男,浙江大學副教授。

教育經歷

2006年-2011年,清華大學,航天航空學院,研究生學歷/碩士、博士,力學專業
2002年-2006年,清華大學,航天航空學院,本科/學士,力學專業

工作經歷

2018.9至今,浙江大學,航空航天學院,副教授

2016.7-2018.8,北京理工大學,宇航學院力學系,副教授

2011.8-2016.6,北京理工大學,宇航學院力學系,講師

2012.6-2012.7,澳大利亞CSIRO–Computational and Simulation Sciences TCP,訪問學者

主要研究領域獲獎情況社會兼職教學工作

分子動力學,研究生課程
材料力學,本科生課程

近年來主要發表論文

Dechang Li, Baohua Ji*:Predicted Rupture Force of a Single Molecular Bond Becomes Rate Independent at Ultralow Loading Rates. Physical Review Letters 02/2014; 112(7):078302., DOI:10.1103/PhysRevLett.112.078302

Dechang Li*, Ming S Liu*, Baohua Ji*:Mapping the Dynamics Landscape of Conformational Transitions in Enzyme: The Adenylate Kinase Case. Biophysical Journal 08/2015; 109(3):647-60., DOI:10.1016/j.bpj.2015.06.059

Bing Bu, Michael Crowe, Jiajie Diao*, Baohua Ji*,Dechang Li*:Cholesterol suppresses membrane leakage by decreasing water penetrability. Soft Matter 05/2018; 14(33–38)., DOI:10.1039/C8SM00644J

Bing Bu, Zhiqi Tian,Dechang Li*, Baohua Ji*:High Transmembrane Voltage Raised by Close Contact Initiates Fusion Pore. Frontiers in Molecular Neuroscience 12/2016; 9:136., DOI:10.3389/fnmol.2016.00136

Dechang Li, Ming S Liu*, Baohua Ji*, Kehchih Hwang, Yonggang Huang*:Coarse-grained molecular dynamics of ligands binding into protein: The case of HIV-1 protease inhibitors. The Journal of Chemical Physics 07/2009; 130(21):215102., DOI:10.1063/1.3148022

Bing Bu, Xin Tong,Dechang Li*, Yachong Hu, Wangxiao He, Chunyu Zhao, Rui Hu, Xiaoqing Li, Yongping Shao, Cong Liu, Qing Zhao*, Baohua Ji*, Jiajie Diao*:N-Terminal Acetylation Preserves α-Synuclein from Oligomerization by Blocking Intermolecular Hydrogen Bonds. ACS Chemical Neuroscience 07/2017; 8(10)., DOI:10.1021/acschemneuro.7b00250

Sijie Wan, Qi Zhang, Xiaohang Zhou,Dechang Li, Baohua Ji, Lei Jiang, Qunfeng Cheng*:Fatigue Resistant Bioinspired Composite from Synergistic Two-Dimensional Nanocomponents. ACS Nano 06/2017; 11(7)., DOI:10.1021/acsnano.7b02706

Yuan Cheng, Leng-Duei Koh, Fan Wang,Dechang Li, Bahua Ji, Jingjie Yeo, Guijian Guan, Mingyong Han*, Yong-Wei Zhang*:Carbon Nanoscroll-Silk Crystallite Hybrid Structure with Controllable Hydration and Mechanical Properties. Nanoscale 06/2017; 9(26)., DOI:10.1039/C7NR01428G

Xiaohang Zhou,Dechang Li*, Sijie Wan, Qunfeng Cheng, Baohua Ji*:In silicon testing of the mechanical properties of graphene oxide-silk nanocomposites. Acta Mechanica 11/2017;, DOI:10.1007/s00707-017-2017-y

Bing Bu,Dechang Li*, Jiajie Diao, Baohua Ji*:Mechanics of water pore formation in lipid Membrane underelectric field. Acta Mechanica Sinica 02/2017; 33(2):234-242., DOI:10.1007/s10409-017-0635-1

Zhongzhong Cui,Dechang Li*, Baohua Ji*:Effect of curvature on the behaviors of confined water layers. International Journal of Applied Mechanics 11/2015; 7(6)., DOI:10.1142/S1758825115500842

Yuan Cheng, Leng-Duei Koh,Dechang Li, Baohua Ji, Yingyan Zhang, Jingjie Yeo, Guijian Guan, Ming-Yong Han*, Yong-Wei Zhang*:Peptide-Graphene Interactions Enhance the Mechanical Properties of Silk Fibroin. ACS Applied Materials & Interfaces 09/2015;, DOI:10.1021/acsami.5b05615

Changjian Xu,Dechang Li*, Yuan Cheng, Ming Liu, Yongwei Zhang, Baohua Ji*:Pulling out a peptide chain from β-sheet crystallite: Propagation of instability of H-bonds under shear force. Acta Mechanica Sinica 05/2015; 31(3)., DOI:10.1007/s10409-015-0404-y

Ying Lai, Lin Zhao, Bing Bu, Xiaochu Lou,Dechang Li, Baohua Ji, Jiankang Liu, Jiajie Diao*, Yeon-Kyun Shin*:Lipid molecules influence early stages of yeast SNARE-mediated membrane fusion. Physical Biology 04/2015; 12(2)., DOI:10.1088/1478-3975/12/2/025003

Xiaofeng Chen,Dechang Li, Baohua Ji, Bin Chen*:Reconciling bond strength of a slip bond at low loading rates with rebinding. EPL (Europhysics Letters) 03/2015; 109(6):68002., DOI:10.1209/0295-5075/109/68002

Dechang Li*, Baohua Ji*:Crucial Roles of Bond Rebinding in Rupture Behaviors of Single Molecular Bond at Ultralow Loading Rates. International Journal of Applied Mechanics 02/2015; 7(1):1550015., DOI:10.1142/S1758825115400153

Zhiyang Xu,Dechang Li*, Baohua Ji:Quantification of the stiffness and strength of cadherin ectodomain binding with different ions. Theoretical and Applied Mechanics Letters 05/2014; 4(3):034001., DOI:10.1063/2.1403401

Yuan Cheng, Leng-Duei Koh,Dechang Li, Baohua Ji, Ming-Yong Han*, Yong-Wei Zhang*:On the strength of -sheet crystallites of Bombyx mori silk fibroin. Journal of The Royal Society Interface 04/2014; 11(96):20140305., DOI:10.1098/rsif.2014.0305

Dechang Li, Baohua Ji*:Free energy calculation of single molecular interaction using Jarzynski's identity method: The case of HIV-1 protease inhibitor system. Acta Mechanica Sinica 06/2012; 28(3)., DOI:10.1007/s10409-012-0112-9

Dechang Li, Ming S Liu*, Baohua Ji*, Keh-Chih Hwang, Yonggang Huang*:Identifying the Molecular Mechanics and Binding Dynamics Characteristics of Potent Inhibitors to HIV-1 Protease. Chemical Biology & Drug Design 05/2012; 80(3):440-54., DOI:10.1111/j.1747-0285.2012.01417.x

Ran Xu, Bin Liu*, Xiaoqiao He,Dechang Li:Kinetic Energy-Based Temperature Computation in Non-Equilibrium Molecular Dynamics Simulation. Journal of Computational and Theoretical Nanoscience 03/2012; 9(3):428.

Dechang Li, Baohua Ji*, Keh-Chih Hwang, Yonggang Huang:Strength of Hydrogen Bond Network Takes Crucial Roles in the Dissociation Process of Inhibitors from the HIV-1 Protease Binding Pocket. PLoS ONE 04/2011; 6(4)., DOI:10.1371/journal.pone.0019268

Yuan Cheng*,Dechang Li, Baohua Ji, Xinghua Shi, Huajian Gao:Structure-based design of carbon nanotubes as HIV-1 protease inhibitors: Atomistic and coarse-grained simulations. Journal of molecular graphics & modelling 09/2010; 29(2):171-7., DOI:10.1016/j.jmgm.2010.05.009

Dechang Li, Baohua Ji*, Kehchih Hwang, Yonggang Huang*:Crucial Roles of the Subnanosecond Local Dynamics of the Flap Tips in the Global Conformational Changes of HIV-1 Protease. The Journal of Physical Chemistry B 02/2010; 114(8):3060-3069., DOI:10.1021/jp1005549

Dechang Li, Baohua Ji*, Kehchih Hwang, Yonggang Huang*:Coarse Grained Modeling of Biopolymers and Proteins: Methods and Applications. International Journal of Applied Mechanics 03/2009; 01(01)., DOI:10.1142/S1758825109000034

李德昌, 季葆華*, 黃永剛*, 黃克智: 生物大分子自組織坍塌行為的研究. 醫用生物力學 01/2007; 22(01): 40-49.

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李德昌

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