圖書信息
出版社: 科學出版社; 第1版 (2009年1月1日)
叢書名: 國外化學名著系列影印版9
平裝: 1199頁
正文語種: 英語
開本: 16
ISBN: 9787030238573
條形碼: 9787030238573
尺寸: 23.6 x 16.8 x 4.8 cm
重量: 1.4 Kg
作者簡介
作者：(美國)卡雷 (Carey.F.A.) (美國)松德貝里 (Sundberg.R.J.)
內容簡介
《高等有機化學:結構與機理(第5版)》自從1997年面世以來，《高等有機化學》作為學科首選教材的地位一直沒有動搖過，廣泛地覆蓋了有機化合物的結構、反應活性及合成。她的第五版相對2001年出版的第四版進行了大幅度的修訂，更新了學科發展的相關資料，內容組織更加清晰明朗，特別是計算化學部分。Part A從化合物結構和立體化學基礎概念講起，涉及有機化學反應熱力學和動力學的方方面面。主要反應類型涵蓋親核取代反應、加成反應、碳負離子和羰基化學反應、芳環取代反應、周環反應、自由基反應和光化學反應。每章後附有習題精選及解答習題的推薦參考文獻。
目錄
Preface
Acknowledgment and Personal Statement
Introduction
Chapter 1 Chemical Bonding and Molecular Structure
Introduction
1.1 Description of Molecular Structure Using Valence Bond Concepts
1.1.1 Hybridization
1.1.2 The Origin of Electron-Electron repulsion
1.1.3 Electronegativity and Polarity
1.1.4 Electronegativity Equalization
1.1.5 Differential Electronegativity of Carbon Atoms
1.1.6 Polarizability, Hardness, and softness
1.1.7 Resonance and conjugation
1.1.8 Hyperconjugation
1.1.9 Covalent and van der Waals radii of Atoms
1.2 Molecular Orbital Theory and Methods
1.2.1 The Hiickel MO Method
1.2.2 Semiempirical MO Methods
1.2.3 Ab Initio Methods
1.2.4 Pictorial Representation of MOs for Molecules
1.2.5 Qualitative Application of MO Theory to Reactivity: Perturbational MO Theory and Frontier Orbitals
1.2.6 Numerical Application of MO Theory
1.3 Electron Density Functionals
1.4 Representation of Electron Density Distribution
1.4.1 Mulliken Population Analysis
1.4.2 Natural Bond Orbitals and Natural Population Analysis
1.4.3 Atoms in Molecules
1.4.4 Comparison and Interpretation of Atomic Charge Calculations
1.4.5 Electrostatic Potential Surfaces
1.4.6 Relationships between Electron Density and Bond Order
Topic 1.1 The Origin of the Rotational (Torsional) Barrier in Ethane and Other Small Molecules
Topic 1.2 Heteroatom Hyperconjugation (Anomeric Effect) in Acyclic Molecules
Topic 1.3 Bonding in Cyclopropane and Other Small Ring Compounds
Topic 1.4 Representation of Electron Density by the Laplacian Function
Topic 1.5 Application of Density Functional Theory to Chemical Properties and Reactivity
T 1.5.1 DFT Formulation of Chemical Potential, Electronegativity, Hardness and Softness,and Covalent and van der Waal Radii
T 1.5.2 DFT Formulation of Reactivity——The Fukui Function ..
T 1.5.3 DFT Concepts of Substituent Groups Effects
General References
Problems
Chapter 2 Stereoehemistry, conformation, and Stereoselectivity.. "
Introduction
2.1 Configuration
2.1.1 Configuration at Double Bonds
2.1.2 Configuration of Cyclic Compounds
2.1.3 Configuration at Tetrahedral Atoms
2.1.4 Molecules with Multiple Stereogenic Centers
2.1.5 Other Types of Stereogenic Centers
2.1.6 The Relationship between Chirality and Symmetry
2.1.7 Configuration at Prochiral Centers
2.1.8 Resolution——The Separation of Enantiomers
2.2 Conformation
2.2.1 Conformation of Acyclic Compounds
2.2.2 Conformations of Cyclohexane Derivatives
2.2.3 Conformations of Carbocyclic Rings of Other Sizes
2.3 Molecular Mechanics
2.4 Stereoselective and Stereospecific Reactions
2.4.1 Examples of Stereoselective Reactions
2.4.2 Examples of Stereospecific Reactions
2.5 Enantioselective Reactions
2.5.1 Enantioselective Hydrogenation
2.5.2 Enantioselective Reduction of Ketones
2.5.3 Enantioselective Epoxidation of Allylic Alcohols
2.5.4 Enantioselective Dihydroxylation of Alkenes
2.6 Double Stereodifferentiation: Reinforcing and Competing Stereoselectivity
Chapter 3 Strucral Effects on Stability and Reactivity
Chapter 4 Nucleophilic Substitution
Chapter 5 Polar Addition and Elimination Reactions
Chapter 6 Carbanions and Other Carbon Nucleophiles
Chapter 7 Addition,Condensation and Substitution Reactions of Carbonyl Compounds
Chapter 8 Aromatictity
Chapter 9 Aromatic Substitution
Chapter 10 concerted Pericyclic Reactions
Chapter 11 Free Radical Reactions
Chapter 12 Photochemistry
References to Problems
Index
