個人簡介
劉鳳華主持和副主持國家自然科學基金3項,主持國家十一五科技支撐計畫課題2項;主持市科委重大科技攻關課題,進行新中獸藥國標二類藥的研製開發;4次主持北京市自然科學基金重點及面上課題;主持禽用系列中獸藥10多項新獸藥開發並獲得新獸藥證書。獲北京市人民政府農業推廣二等獎(第一完成人),申報了4項國家發明專利。主編、副主編、參編著作或教材10餘部,家畜環境衛生學獲得北京市高等教育精品教材。在國內外核心期刊上發表論文70多篇。獲得首都教育先鋒科技創新個人、北京市三八紅旗獎章榮譽。北京市房山區政府農業顧問。
教學工作
承擔動物科學、動物醫學本科家畜環境衛生學、動物行為學、飼料添加劑等課程;承擔研究生動物醫學進展,畜禽中藥添加劑專題課程。
2010年指導的研究生在本年度全國畜牧獸醫學會學術年會上獲得“全國畜牧獸醫學會學術獎”。北京農學院優秀研究生畢業論文獎。
科研成果
2009年主持的“石香顆粒”, 農業部三類新獸藥(2009)新獸藥證字37號,農業部新藥審評中心(第一完成人)。
主持禽用系列中獸藥10項(四類)新獸藥開發並獲得新獸藥證書。
作為主持人和副主持人進行豬、牛中獸藥的開發研製。其中,以第一完成人獲得禽用系列中獸藥的研發與推廣獲得北京市人民政府農業推廣二等獎,地方科技進步二等獎。
申報三項國家發明專利。“評價暑熱證及中藥藥效的基因晶片”, “一種用於防治畜禽熱應激綜合症的藥物”, “一種黃柏總生物鹼的提取方法”。主編由中國農業科技出版社出版的《天然物飼料添加劑研製指南》,主編《家畜環境衛生學》獲得北京市精品教材及普通高等教育十一五精品課程建設教材稱號。中國農業出版社出版的《安全優質肉雞生產》及《安全優質肉羊生產》等10多部;在國內外發表論文70多篇。
科研項目
2008~2010年主持國家十一五科技支撐計畫中獸藥添加劑研製與開發(2008BADB4B07,778萬元);
2010~2014年主持農業部行業科技專項“抗家畜生產運輸應激中獸藥的研製與開發”(201003060,150萬)
2008~2010年主持國家自然科學基金“熱應激對豬小腸黏膜結構與功能的影響及其中藥調控機制(30771566,35萬元)”,副主持國家自然科學基金“胃腸激素與脾失健運相關性及四君子湯調控機理研究(30771591,33萬元)”;
2010-2012 主持北京市教委學術創新團隊計畫“畜禽中藥添加劑的藥效學評價與研製開發”(150萬元)
2008~2010年主持北京市自然科學基金“熱應激對豬腸黏膜屏障功能的影響及其中藥調控研究(項目編號:6082007,11萬元)”;
2006~2010年主持國家十一五科技支撐計畫分課題“安全環保型中獸藥的研製與套用”抗病毒中獸藥研製與開發(2006BAD31B05-2,114萬元);
2005-2007年主持北京市科委重大攻關課題“畜禽抗應激沖劑的研發與推廣”(Y0705003041631,150萬元,企業另配套30萬元),進行新中獸藥二類藥的研製開發;
2003-2005主持年北京市自然科學基金B類及北京市教委重點課題“清涼沖劑的有效部分及其藥理研究”(KZ20 0310020007,30萬元);
1997年、1995年2-次主持北京市自然科學基金課題“蛋雞熱應激及其中藥調控”(6952008,6972006,共18萬元)
北京市科委課題“豬的熱應激及其中藥調控研究” (954414800,15萬元),主持國標三類中獸藥清涼沖劑的研製開發;
發表論文
科研論文(全部為第一作者或通訊作者):
1. Jin Yu, Fenghua Liu, Peng Yin,Xiaoyu Zhu, Guiling Cheng, Ning Wang,An Lu, Weili Luan, Nuowei Zhang, JiefengLi, Kaijun Guo, Yulong Yin,Huichuan Wang, , Jianqin Xu. Integrating miRNA andmRNA Expression Profiles in Response to Heat Stress-Induced Injury in Rat SmallIntestine. Functional & Integrative Genomics. 2011,11:203-213. IF 3.82.
2. Liu F H, Yin J D, Du M, Yan P S,Xu J Q, Zhu X Y, Yu J. Heat Stress induced Damage to Porcine Small IntestinalEpithelium associated with Down-Regulation of Epithelial Growth Factor (EGF)Signaling. Journal of Animal Science. 2009,6(87):1941-1949 , IF 2.466.
3. Yu Jin, Yin Peng, Liu Fenghua..Involvement of ERK1/2 signaling pathway in heat stress-induced damage andexpression change of growth factors in rat jejunum and IEC-6 cells. InternationalJournal of Hyperthermia. 2010,10; 26(6): 538–555, Corresponding author. IF 2.713.
4. Jin Yu, Peng Yin, Fenghua Liu,Xiaoyu Zhu, Guilin Cheng, An Lu, Weili Luan, Jianqin Xu. Effect of heat stresson porcine small intestine: a study of morphological and gene expression. ComparativeBiochemistry and Physiology, Part A 156 (2010) 119–128. IF 2.196.
5. Jin Yu,Yu J, Liu F, Yin P, Zhao H, Luan W,Hou X, Zhong Y, Jia D, Zan J, Ma W, Shu B, Xu J. Involvement of oxidativestress and Mitogen-Activated Protein Kinase signaling pathways in heat stress-inducedinjury in the rat small intestine. Stress . 2013 Jan;16(1):99-113. IF3.2
6. An Lu, Huichuan Wang, XiaolinHou, Huanrong Li, Guilin Cheng, Ning Wang, Xiaoyu Zhu, Jin Yu, Weili Luan, FenghuaLiu, Jianqin Xu. Microarray analysis of gene expression profiles of rat smallintestine in response to heat stress. Journal of Biomolecular Screening.2011 16(6):655-67 IF 2. 5.
7. Jiefeng Li, Huanrong Li, NuoweiZhang, Wuren Ma, Guilin Cheng, Faqiang Liu, Fenghua Liu, Jianqin Xu Effects ofAstragalus polysaccharide on peripheral blood lymphocytes in pigs inoculated withFoot-and-mouth disease virus vaccine. International Journal of BiologicalMacromolecules. 2011 1;49(3):362-8. IF 2.366
8. K. J. Guo, W. Wang, X. Z. Song,F. H. Liu, J. Q. Xu, I. Zoccarato. Antioxidant function of the active componentsof some traditional Chinese medicines. Journal of Animal Science. 2011, IF 2.5..
9. Xiaoxi Liu, Huanrong Li, An Lu,Yougang Zhong, Xiaolin Hou1,Ning Wang, Dan Jia, Junlan Zan, Hong Zhao, JianqinXu, &Fenghua Liu Reduction of intestinal mucosal immune function in heat-stressed rats and bacterial translocation. Int JHyperthermia. 2012;28(8):756-65, (SCI: IF1.9).
10. Dan JIA, Fenghua LIU, WeiliLUAN, Kaijun GUO, An LU, Jin YU. 2010. The research of apoptosis in the swinesmall intestine epithelium treated by heat stress. 2010 First internationalconference on cellular, molecular biology, biophysics and bioengineering. VI:260-264.(EI收錄)
11. Song X Z, Xu J Q, Wang T, Liu FH. Chinese medicine granule affects the absorption and transport of glucose inporcine small intestinal brush border membrane vesicles under heat stress. Asian-Australasian journal of animal sciences. 2009, 20:246-254. IF0.875 (Corresponding author)
12. Song X Z, Xu J Q, Wang T, Liu FH. Traditional Chinese medicine decoction enhances growth performance and intestinalglucose absorption in heat stressed pigs by up-regulating the expressions ofSGLT1 and GLUT2 mRNA. Livestock Science. 128 (2010) 75–81, Corresponding author) IF 1.41
13. Zhu Xiaoyu; Ming Wang; YujieWang; Fenghua Liu; Tongquan Yu; Jianqin Xu; Jin Yu. Taguchi approach foranti-heat stress prescription compatibility in mice spleen lymphocytes in vitro.Archives of Pharmacal Research. 2011, 34(7):1125-33 IF 1.588.
14. Anru Wang, Fenghua Liu, ZhepengWang, Xue Jiang, Wei Wang, Kedao Teng, Jianqin Xu. Pathological Study of SPFChickens Experimentally Infected with a Chinese IBDV Strain BC6/85. AsianJournal of Animal and Veterinary Advances. 2010. 6: 36-50.. IF 1.6.
15. Hehui Qiu, Fenghua Liu, JianqinXu, Xiaoyu Zhu, Juan Zhao, Yujie Zhang. Effects of Astragalus Polysaccharideson Associated Immune Cells and Cytokines in Immunosuppressive Dogs. Procedia inVaccinology 2 (2010) 26–33 ISTP
16. GUO Kaijun, LIU Fenghua, LULin, Biagini Davide, Lazzaroni Carla and Zoccarato Ivo. Productive Performanceof Double-Muscled Piemontese Cull Cows in Finishing Period. AgriculturalSciences in China. 2010, 9(5): 101-105 SSCI
17. Guilin Cheng, Shufang Xu, Defeng Cui, Xin Chen, Fenghua Liu, An Lu, WeiliLuan, Jianqin Xu. Antimicrobial activity of main components DADS from Garlicoil against four pathogenic bacteria in animals in vitro. The journal oftraditional veterinary medicine. 2010, 18(1): 151-156.
18. Hong Dong, Yougang Zhong, FenghuaLiu, Kai Yang, Jin Yu, Jianqin Xu. RegulatingEffects and Mechanisms of Chinese Medicine Decoction on Growth and Gut HormoneExpression in Heat Stressed Pigs。Livestock Science. 143 (2012), pp. 77-84 IF 1.41
19. Guo X,Wang L,Cui D,Ruan W,Liu F,Li H.Arch Virol. Differential expression of theToll-like receptor pathway and related genes of chicken bursa afterexperimental infection with infectious bursa disease virus. 2012.157(11):2189-99. IF 1.41