劉振輝[中國海洋大學海洋生命學院教授]

劉振輝[中國海洋大學海洋生命學院教授]
劉振輝[中國海洋大學海洋生命學院教授]
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劉振輝,男,1971年10月生,山東安丘人。博士,中國海洋大學海洋生命學院教授,碩士生導師,生物系副主任。教育部新世紀優秀人才。

基本信息

人物經歷

2003年9月至今,中國海洋大學海洋生命學院講師、副教授、教授,主要從事原索動物和魚類的發育、免疫與進化研究。山東省“泰山學者”研究團隊主力成員。

2007.2-2008.2,法國歐洲味覺研究中心博士後,德國漢堡大學分子神經研究所博士後。從事味覺的分子機理研究。

2000.9-2003.7, 中國海洋大學海洋生物學專業,獲博士學位。

1997.9-2000.7,中國海洋大學水產養殖專業,獲碩士學位。

研究方向

海洋生物功能基因研究;進化與發育研究;味覺的分子機制與進化研究。

主要貢獻

研究課題

海洋“863”重點項目“海洋模式生物文昌魚免疫防禦的關鍵基因研究” (2008AA092603),132萬元,2008-2012;2008年獲教育部新世紀優秀人才項目支持“魚類卵黃脂磷蛋白免疫新功能的分子機理研究”,50萬元,2009-2011;留學回國啟動基金,3萬元,2010-2012。國家自然科學基金 “文昌魚CD19類蛋白的鑑定及基因克隆與進化研究”(30500256),22萬元,2006.1-2008.12;海洋“863” 子課題 “海洋重要動物免疫相關基因的研究與開發”(2005AA626012),109萬元, 2005-2006。

發表論文

已發表論文49篇,其中在SCI源期刊上發表論文37篇。

主要代表作:

1. Yanling Sun, Zhenhui Liu*, Shicui Zhang. Tissue distribution, developmental expression and up-regulation of p8 transcripts on stress in zebrafish. Fish & Shellfish Immunology,(2010) 1-6.SCI, IF: 3.1; 通訊作者。

2. Claire Fenech, Lila Patrikainen, Daniel S. Kerr, Sylvie Grall, Zhenhui Liu, Fabienne Laugerette, Bettina Malnic and Jean-Pierre Montmayeur. Ric-8A, a Gα protein guanine nucleotide exchange factor potentiates taste receptor signaling. Frontiers in Cellular Neuroscience, October 2009 | Volume 3 | Article 11 | 1. doi: 10.3389/neuro.03.011.2009.

3. Zhenhui Liu*, Yanping Xu, Ling Wu and Shicui Zhang. Evolution of galanin receptor genes: insights from the deuterostome genomes.

Journal of Biomolecular Structure and Dynamics. 2010, accepted. IF:1.4. 4. Zhenhui Liu*, Lei Li, Hongyan Li, Shicui Zhang, Guangdong Ji, Yanling Sun. EST analysis of the immune-relevant genes in Chinese amphioxus challenged with lipopolysaccharide. Fish & Shellfish Immunology 26 (2009) 843–849. IF: 3.1;

5. Zhenhui Liu*, Yanling Sun, Naiguo Liu, Ningning Fan, Shicui Zhang. Characterization, expression, and response to stress of p8 gene in amphioxus. Fish & Shellfish Immunology. 27 (2009) 407–413. IF: 3.1;

6. Jing LUAN, Zhenhui LIU, Shicui ZHANG, Hongyan LI, Chunxin FAN, Lei LI. Characterization, Evolution and Expression of the Calmodulin1 Genes from the Amphioxus Branchiostoma belcheri tsingtauense. Acta Biochimica et Biophysica Sinica. 2007,39 (4), 255–264. (通訊作者)。IF: 1.0;

7. Zhenhui Liu, Shicui Zhang, Hongyan Li, Jing Luan, Yongjun Wang, Lei Wang and Jianhan Xiang. Characterization and expression profile of AmphiCD63 encoding a novel member of TM4SF proteins from amphioxus Branchiostoma belcheri tsingtauense. DNA Sequence.2005, 16(3):195-201. IF: 0.6;

8. Zhenhui Liu, Shicui Zhang, Mei Liu, Yongjun Wang, and Anlong Xu, Evolution and expression of the amphioxus AmphiHMGB gene encoding a HMG-box protein. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. 2004, 137:131-138. IF: 1.6;

9. Zhenhui Liu, Shicui Zhang, Mei Liu and Anlong Xu. Identification of the Ribosomal Protein S15a and L19 from the Amphioxus Branchiostoma belcheri tsingtauense. OPHELIA. 2004, 58(1): 23-27. IF: 0.9;

10. Zhenhui Liu, Jie Kong, Xiaowen Sun and Jingyao Deng. Application of RAPD technique for identification in three different stocks of Penaeus chinensis. Acta Oceanologica Sinica. 2003, 22(4): 629-634. IF: 0.4;

11. Zhenhui Liu, Zhang S., Yuan J., Sawant M.S., Wei J., and Xu A. Molecular Cloning and Phylogenetic Analysis of AmphiUbf80, a New Member of Ubiquitin Family from the Amphioxus Branchiostoma belcheri tsingtauense. Current Science 2002, 83, 50-53. IF: 0.6;

12. N Liu, S Zhang, Z. Liu. Characterization and expression of gamma-interferon-inducible lysosomal thiol reductase (GILT) gene in amphioxus Branchiostoma belcheri with implications for GILT in innate immune response. Mol Immunol. 2007 Apr;44(10):2631-7. IF 3.7.

13. C Fan, S Zhang, Z. Liu. Identification and expression of a novel class of glutathione-S-transferase from amphioxus Branchiostoma belcheri with implications to the origin of vertebrate liver. Int J Biochem Cell Biol. 2007;39(2):450-61. IF 4.0.

14. L Wang, S Zhang, Z. Liu. Characterization and expression of amphioxus ApoD gene encoding an archetype of vertebrate ApoD proteins. Cell Biol Int. 2007 Jan;31(1):74-81. IF 1.2.

15. Jinduo Yuan, Shicui Zhang, Zhenhui Liu, Zhidong Luan, and Gengxi Hu. Cloning and phylogenetic analysis of an amphioxus myogenic bHLH gene AmphiMDF. Biochemical and Biophysical Research Communications, 2003, 301: 960-967. IF 3.0.

16. M. Liu, S. Zhang, Z. Liu, and A. Xu. Characterization, organization and expression of AmphiLysC, an acidic c-type lysozyme gene in amphioxus Branchiostoma belcheri tsingtauense. Gene, 2006, 367: 110-117. IF 2.7.

17. He Y, Tang B, Zhang S, Liu Z, Zhao B, Chen L. Molecular and immunochemical demonstration of a novel member of Bf/C2 homolog in amphioxus Branchiostoma belcheri: implications for involvement of hepatic cecum in acute phase response.Fish Shellfish Immunol. 2008 Jun;24(6):768-78. IF 3.2.

18. Tian J, Zhang S, Liu Z, Zhuang Y, Wang Y, Jiang S. Characterization and tissue-specific expression of phosphatidylcholine transfer protein gene from amphioxus Branchiostoma belcheri.Cell Tissue Res. 2007 Oct;330(1):53-61. IF 2.6.

19. Zhao B, Zhang S, Wang Y, Liu Z, Kong D. Characterization and expression of p23 gene in the amphioxus Branchiostoma belcheri.Comp Biochem Physiol B Biochem Mol Biol. 2006 Sep;145(1):10-5. IF 1.6.

20. Wang Y,Zhang S,Liu Z. Characterization and Expression of AmphiCL Encoding Cathepsin L Proteinase from Amphioxus Branchiostoma belcheri tsingtauense. Marine Biotechnology 2005,7: 279-286. IF 1.5.

獲獎記錄

山東省自然科學獎一等獎一項(第二位),2007年;教育部自然科學獎二等獎一項(第二位),2006年;國家海洋局海洋創新成果一等獎一項(第五位),2004年;山東省高等學校自然科學獎一等獎(第二位),2006年;青島市自然科學一等獎(第二位),2005年;中國海洋大學優秀班主任和中國海洋大學“天泰”優秀教師獎,2006年。

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