伍義行

伍義行,1972生。畢業於浙江大學藥學院,致力於學習和研究藥理與毒理專業,獲醫學博士學位。中國計量學院生命科學學院藥學系教授,主要研究方向:肝臟藥理與毒理學,中藥活性成分與新藥研發,新藥篩選技術體系研究,藥品和藥妝品安全與質量檢測。曾主持國家自然科學基金、浙江省科技計畫、浙江省中醫藥科技計畫等項目。發表論文26篇,其中SCI/EI收錄10篇。申請國家專利4項。

主要專著

[1] Wu YH, Shen E, Hao BJ, Zhang XM, Zhao Y. Effect of Laggera alata on immune liver injury induced by BCG-LPS. The European Association for the Study of the Liver (EASL) monothematic conference on Immune-Mediated Liver Injury, in Hamburg, Germany, 2008.
[2] Wu YH, Yang LX, Wang F, Zhou CX, Shi SY, Mo JX, Wu XM, Zhao Y. Hepatoprotective and antioxidative effects of total phenolics from Laggera pterodonta on chemical-induced injury in primary cultured neonatal rat hepatocytes. Food Chem Toxicol, 2007, 45: 1349-1355. (SCI)
[3] Wu YH, Zhou CX, Li XP, Song LY, Li XP, Shi SY, Mo JX, Chen HY, Bai H, Wu XM, Zhao J, Zhang RP, Hao XJ, Sun HD, Zhao Y. Effect of total phenolics from Laggera alata on acute and chronic inflammation models. J Ethnopharmacol, 2006, 108(2): 243-250. (SCI)
[4] Wu YH, Zhou CX, Li XP, Song LY, Wu XM, Lin WY, Chen HY, Bai H, Zhao J, Zhang RP, Sun HD, Zhao Y. Evaluation of anti-inflammatory activity of the total flavonoids of Laggera pterodonta on acute and chronic inflammation models. Phytother Res, 2006, 20 (7): 585-590. (SCI)
[5] Wu YH, Wang F, Zheng QX, Lu LX, Yao HT, Zhou CX, Wu XM, Zhao Y. Hepatoprotective effect of total flavonoids from Laggera alata against carbon tetrachloride-induced injury in primary cultured neonatal rat hepatocytes and in rats with hepatic damage. J Biomed Sci, 2006, 13 (4): 569-578. (SCI)
[6] Zhou HB, Dong SY, Zhou CX, Hu LH, Wu YH, Li HB, Gong JX, Sun LL, Wu XM, Bai H, Fan BT, Hao XJ, Stockigt J, Zhao Y. Design, synthesis, and SAR analysis of cytotoxic sinapyl alcohol derivatives. Bioorg Med Chem, 2006, 14(6): 2060- 2071. (SCI)
[7] Gong JX, Feng YB, Wang F, Wang YG, Li HB, Wu YH, Hao XJ, Wu XM, Bai H, Stöckigt J, Zhao Y. Preparation of (±)-5,6,7-trioxygenated dihydroflavonols and evaluation of their superoxide radical scavenging activity. Chin Chem Lett, 2006, 17 (4): 449-452. (SCI)
[8] Gong JX, weng LJ, Wang F, Feng YB, Zhou CX, Li HB, Wu YH, Hao XJ, Wu XM, Bai H, Stöckigt J, Zhao Y. Synthesis and antioxidant properties of novel silybin analogues. Chin Chem Lett, 2006, 17 (4): 465-468. (SCI)
[9] 伍義行, 李湘萍, 周長新, 陳海永, 趙軍, 趙昱. 六棱菊總黃酮的抗炎作用研究, 中國藥學雜誌, 2006, 41 (11): 26-29. (EI)
[10] Yu RM, Song LY, Zhao Y, Bin W, Wang L, Zhang H, Wu YH, Ye WC, Yao XS. Isolation and biological properties of polysaccharide CPS-1 from cultured Cordyceps militaris. Fitoterapia, 2004, 75 (5): 465-472. (SCI)
[11] Zhao JH, Zhao F, Wang YG, Li HB, Zhang QJ, Guénard D, Ge QF, Wei EQ, Jiang H, Wu YH, Wang L, Jiang HL, Guéritte F, Wu XM, Cheng CHK, Lee SS, Zhao Y. Synthesis of A/B ring analogs of territrem B and evaluation of their biological activities. Helv Chim Acta, 2004, 87 (7): 1832-1853. (SCI)
[12] 國家發明專利,具抗病毒、抗炎和/或抗菌作用的六棱菊屬提取物及其用途,申請號200510077457.3。
[13] 國家發明專利,水飛薊賓酯類衍生物及其製備方法和用途,申請號200510132509.2。

在研課題

[1] 國家自然科學基金項目,六棱菊抗B肝活性成分及其作用機理研究,30701049
[2] 浙江省科技計畫項目,肝細胞凋亡動物模型建立及評價,2008F80016
[3] 浙江省中醫藥科技計畫項目,火絨草有效部位及其保肝作用研究, 2008CA088
[4] 浙江省中醫藥科技計畫項目,白藜蘆醇干預急性心肌梗死後左室重構作用研究,2007CB196
[5] 中國計量學院123人才計畫項目,浙貝母鎮咳祛痰新藥前期研究,2006RC19

主要科研項目

主要實施完成的科研課題有:[1] 國家“九.五”攻關項目,中獸藥的研製與開發,96-005-02-04-05;[2] 農業部新獸藥工程重點實驗室基金,火絨草活性成分的研究,KL-97-054;[3]甘肅省中青年基金,甘肅火絨草抗菌活性成分研究,YS981-A21-012;[4] 浙江省中醫藥科技重點研發計畫,民族藥六棱菊有效活性部位的臨床前研究,04Z001;[5] 浙江省經貿委中藥現代化專項,海洋活性物質石蓴多糖的研製,2003ZY。

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