人物經歷
學習經歷
1977-1982: 武大病毒系， 本科。
1983-1988: Case Western Reserve University, Biochemistry, 博士。
1988-1992: Harvard University, 博後。
工作經歷
1992-1998: Assistant Professor, UCSD
1998-2002: Associate Professor with Tenure, UCSD
2002-present: Full Professor, UCSD
2004-present: Lecture Professor, 武漢大學生科院。
2011-present: 千人計畫（B）。
主要社會兼職：
科技部蛋白質重大研究計畫專家組成員。
研究方向
RNA processing and regulation
microRNA biogenesis and functions
Transcription and mRNA processing coupling
Functional genomics
Genetics and epigenetics regulation of gene expression
主要貢獻
代表性論文
（部分或完全在武大完成的工作）:
1. Xue, Y-C., Zhou, Y., Wu, T-B., Zhu, T., Ji, X., Zhang, C., Kwon, Y-S., Yeo, G., Sun, H., Fu, X-D.*, and Zhang, Yi* (2009). Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping.Molecular Cell36:996-1006. (*co-corresponding authors).
2.Ji, X and Fu, X-D. (2012). The mediator couples transcription and splicing.Molecular Cell45:433-434.
3.Xiao, R., Tang, P., Yang, B., Huang, J., Zhou Y., Shao C-W., Li, H., Sun, H., Zhang, Y., and Fu, X-D. (2012). Nuclear matrix factor hnRNP U/SAF-A exerts a global control of alternative splicing by regulating U2 snRNP maturation.Molecular Cell45:656-668.
4.Xue, Y-C., Ouyang, K., Huang, J., Zhou, Y., Ouyang, H., Li, H., Wang, G., Wu, Q., Wei, C., Bi, Y., Jiang, L., Cai, Z., Sun, H., Zhang, K., Zhang, Y., Chen, J., and Fu, X-D. (2013) Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.Cell152:82-96.
5. Ji, X., Zhou, Y., Pandit, S., Huang, J., Li, H., Lin, C. L., Rui, X., Burge, C. B., and Fu, X-D. (2013). SR proteins collaborate with 7SK and promoter-associated nascent RNA to release paused polymerase.Cell153:855-868..
