郝健[上海大學教授、博士生導師]

郝健,上海大學教授、博士生導師。畢業於Univ of Florida。

基本信息

人物經歷

1986-1994:上海有機化學研究所,研究實習員、助理研究員,1994-1995:訪問學者,Univ of Florida化學系(Prof W.R.Dolbier, Jr.),1996-1999:博士生,日本岡山大學(Prof Kenji Uneyama),1999-2000:博士後,東京工業大學(Prof. Koichi Mikami),2001:Visiting Assistant Prof,香港科技大學(吳雲東院士),2002-至今:教授,上海大學化學系;2006-至今:博導,上海大學材料學專業2005-至今:上海大學科技處副處長美國化學會(ACS)會員/ Fluorine Division。

研究方向

郝健教授 郝健教授

目前研究領域:含氟雜環化學、含氟功能小分子與OLED材料、有機小分子催化。

主要貢獻

代表論文:

1. 含氟b-胺基酸及其衍生物的合成進展, 彭榮達,郝健, 有機化學,2005,25, 485-495。

2. Grignard Cyclization Reaction of Fluorinated N-Aryl I_midoyl Chlorides. A Novel and Facile Access to the 2-Fluoroalkyl Indoles, Ge, F.; Wang, Z.; Wan, W.; Hao, J.* Synlett,2007, 447-450。

3. One-pot synthesis of 2-trifluoromethyl and 2-difluoromethyl substituted benzo-1,3-diazoles, Ge,F.; Wang, Z.; Wan, W.; Lu, W.; Hao, J.* Tetrahedron Lett. 2007, 48, 3251-3254。

4. 5,5,5-Trifluoro-N-(4-fluorophenyl)-4-hydroxypentana_mide, Wan, W.; Ma, G.; Yuan, Z.; Li, M.; Hao, J.* Acta Cryst. 2007,E63, o1685–o1686。

5. Fluorinated N-[2-(haloalkyl)phenyl]i_midoyl chloride, a key intermediate for the synthesis of2-fluoroalkyl substituted indole derivatives via Grignard cyclization process, Wang, Z.; Ge, F.; Wan, W.; Jiang,H.; Hao, J.* J. Fluorine Chem. 2007,128, 1143-1152。

6. 3-Chloro-1,1,1-trifluoro-3-(triphenylphosphoranylidene)propan-2-one, Wang, Z.; Jiang, H.; Wan, W.; Ge,F.; Hao, J.* Acta Cryst.2007,E63, o3152。

7. Recent Progress in One-pot Synthesis of Fluorinated Building Blocks, Ren, X.; Wan, W.; Jiang, H.; Hao, J.* Mini-Rev. in Org. Chem. 2007,4, 330-337。

8. One-pot Cyclization of 2-Aminophenethyl Alcohols: A Novel and Direct Approach to the Synthesis of N-Acyl Indolines, Wang, Z.; Wan, W.; Jiang, H.; Hao, J.* J. Org. Chem. 2007,72, 9364-9367。

9. 14-Androsta-5,15-dien-3-ol-17-one, Zheng, C.; Yao, S.; Wan, W.; Hao, J.* Acta Cryst.2007,E63, o2651。

10. Fluoroalkyl Substituted (Z)-Dehydro α-Amino Ester as a Building Block for the Fluorine-containing Cyclopropyl α-Amino Esters and Dihydrooxazole, Wan, W.; Gao, Y.; Jiang, H.; Hao, J.* J. Fluorine Chem. 2008,129, 510-514。

11. Synthesis and _characterization of triphenylene derivatives containing two terminal functional grous atthe periphery, Wan, W.*; Wang, P.; Jiang, H.; Hao, J. Mol Cryst Liq Cryst.2008, 482, 42-56。

12. Synthesis and _characterisation of nematic liquid crystalscontaining a trans-decalin ring, Wan, W.* Yang, C.; Jiang, H.; Wang, J. Hao, J. Liq. Cryst.2008,35, 665-673。

13. Ethyl 2-phenyl-5-trifluoromethyl-1,3-thiazole-4-carboxylate, Jiang, H.; Wan, W.; Shao, M.; Hao, J.* Acta Cryst.2008,E64, o2004。

14. Concise Synthesis of ω-Fluoroalkylated Ketoesters. A Building Block for the Synthesis of 6-, 7-, and8-Membered Fluoroalkyl Substituted 1,2-Diaza-3-One Heterocycles, Wan, W.; Hou, J.;Jiang, H.; Wang,Y.; Zhu, S.; Deng, H.; Hao, J.* Tetrahedron,2009, 65, 4214-4219。

15. Recent Progress on the Synthesis of Trifluoromethylated Heterocyclic Compounds Based on ethyl 4,4,4-trifluoroacetoacetate and its Derivatives, Zhu, S.Z.; Song, L.P.; Jin, G.F; Dai, B.F.;Hao, J. Current Org. Chem. 2009,13, 1015-1027。

16. Reductive Amination/Cyclization of ω-Trifluoromethyl Ketoesters. Synthesis of Trifluoromethylated δ-Amino Alcohols and Lactams, Wan, W.; Hou, J.; Jiang, H.; Yuan, Z.; Ma, G.; Zhao, G.; Hao, J.* Eur. J. Org. Chem. 2010,9, 1778-1786。

17. p-TsOH Promoted Fischer Indole Synthesis of Multi-Substituted 2-Trifluoromethyl Indole Derivatives, Jiang, H.; Wang, Y.; Wan, W.; Hao, J.* Tetrahedron, 2010, 66, 2746-2751。

18. Bromotriphenylphosphonium Salt Promoted Tandem One-Pot Cyclization to the Optically Active 2-Aryl-1,3-Oxazolines, Jiang, H.; Yuan, S.; Wan, W.; Yang, K.; Deng, H.; Hao, J.* Eur. J. Org. Chem. 2010,9, 4227-4236。

19. C-9 Fluorenyl Substituted Anthracenes:A Promising New Family of Blue Luminescent Materials, Jing Wang,a Wen Wan,a* Haizhen Jiang, a Yan Gao, a Xueyin Jiang, b Huaping Lin,b Weiming Zhao c and Jian Hao a, d, * Org. Lett. 2010, 12, 3874-3877。

20. A Facile Preparation of 2-Bromodifluoromethyl Benzo-1, 3-diazoles and Application in the Synthesis of gem-Difluoromethylene linked Aryl Ether Compounds, Haizhen Jiang 1*, Shijie Yuan1, Yeshan Cai 1, Wen Wan 1,2, Shizheng Zhu 2 and Jian Hao 1,2*, Molecules, 2011,Special Issue for Fluorine Chemistry, Invited article, Withdrawn, will be submitted to Tetrahedron or EJOC。

21. 含氟砌塊的分子設計、合成及其在合成含氟雜環化合物中的套用-過去、現在與未來,蔣海珍,宋力平*,羅會華,朱仕正,郝健*,上海大學學報(自然科學版),2011,創刊100期特別版,特邀綜述,Submitted。

22. Bromotriphenylphosphonium Salt Promoted One-pot Synthesis of 2-Fluoroalkyl Substituted 1,3-i_midazolines and 1,3-Oxazolines, Haizhen Jiang, Shijie Yuan, Yeshan Cai, Shizheng Zhu, Jian Hao*, J. Fluorine Chemistry, 2011, Invited article, Special Issue for Prof Weiyuan Huang's 90th Birthday,accepted。

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