王艷麗[上海大學腫瘤精準靶向研究中心主任,研究員]

王艷麗, 女,博士生導師。2010年獲工學博士學位。 現為上海大學環境與化學工程學院研究員, 上海大學腫瘤精準靶向研究中心主任。

先後作為客座副教授,訪問學者在美國哈佛大學,美國密西根大學,美國克萊姆森大學交流訪問學習。 主要研究方向為:1. 納米螢光靶向材料在腫瘤診斷中的套用;2.納米藥物設計及其在腫瘤治療中的套用;3. 腫瘤標記物檢測試劑盒的開發;4. 納米材料的生物安全性。作為項目負責人主持國家自然科學基金項目3項,參加國家重點基礎研究發展計畫(973計畫)項目2項,主持市教委等項目多項,參加國家自然科學基金項目多項。在Nature Communications等國際著名期刊上發表SCI收錄論文40多篇,參與編著專著1部,申請發明專利15項,應邀參加國際會議報告10多次

代表性論文

1.Z. Lei#, L. Ding#, C. Yao #, F. Mo#, C. Li, Y. Huang, X. Yin, Y. Zhang, Q. Lu, Y. Wang*, A Highly Efficient Tumor-Targeting Nanoprobe with a Novel Cell Membrane Permeability Mechanism, Advanced Materials. 2019 , DOI: 10.1002/adma.201807456, IF=21.95
2.L. Ding, C. Yao, X. Yin, C. Li, Y. Huang, M. Wu, B. Wang, X. Guo, Y. Wang*, M. Wu*, Size, shape and protein corona determine cellular uptake and removal mechanisms of gold nanoparticles, Small, 2018. DOI:10.1002/smll.201801451 IF=9.598
3.L. Wang†, Y. L. Wang†, T. Xu, H. Liao, C. Yao, Z. Li, Z. Chen, Y. Liu, M. Wu*, L. Sun*, D. Pan*, Gram-scale synthesis of single-crystalline graphene quantum dots with superior optical properties, Nature communication, 2014, 5:5357.
4.G. M. DeLoid+, Y.L. Wang+, K. Kapronezai, L. R. Lorente, R. Zhang, G. Pyrgiotakis, N. V. Konduru , M. Ericsson, J. C. White, R. De La Torre-Roche, H. Xiao, D. J. McClements, P. Demokritou,An integrated methodology for assessing the impact of food matrix and gastrointestinal effects on the biokinetics and cellular toxicity of ingested engineered nanomaterials, Particle and Fibre Toxicology (2017) 14:40. IF=8.9
5.A. Cao, Z. Ye, Z. Cai, E. Dong, X. Yang, G. Liu, X. Deng, S. Y. Wang, T. Yang, H. Wang,* M. Wu, Y. Liu,A facile method to encapsulate proteins in silica nanoparticles: encapsulated green fluorescent protein as a robust fluorescence probe, Angew. Chem. Int. Ed., 2010, 49, 3022-3025. IF=12.1
6.J. Wang, C. Yao, B. Shen, X. Zhu, L. Shi, Y. Zhang, J. Liu*, Y. Wang*, L. Sun*, Upconversion-magnetic Carbon Sphere with Pomegranate Structure for Near-infrared Light Triggered Bioimaging and Photothermal Therapy, Theranostics, 2019. IF=8.537,
7.Wang YL*, Yao CJ, Li CC, Ding L, Liu J, Dong P, Fang HP, Lei ZD, Shi GS, Wu MH. Excess titanium dioxide nanoparticles on the cell surface induce cytotoxicity by hindering ion exchange and disrupting exocytosis processes. Nanoscale. 2015, 7(30): 13105-13115. IF=7.76
8.. L. Wang, L. Yuan, C. Yao, L. Ding, C. Li, J. Fang, K. Sui,Y. F. Liu*, Minghong Wu*, Combined toxicity study of zinc oxide nanoparticles and Vitamin C in food additives, nanoscale, 2014, 6: 15333-15342. IF=7.76
9.Y.L. Wang, Q. Wu, K. Sui, X. Chen, J. Fang, X. Hu, M. Wu, Y. Liu, A Quantitative Study of Exocytosis of Titanium Dioxide Nanoparticles from Neural Stem Cells, Nanoscale, 2013, 5(11):4737-4743. IF=7.76

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