人物經歷
中國科學技術大學副教授。2002年獲中國科學技術大學博士學位。
近年來主要從事環境污染物納米材料、鉛、鋁等對學習記憶的影響及其機制的研究,先後主持校級、省級、國家級自然科學基金,並參與了實驗室國家自然科學基金重點項目、國家科技部973項目及中科院創新項目。以主要作者發表相關論文10多篇。先後獲香港求是獎、安徽省自然科學論文一等獎、教育部自然科學二等獎(第二完成人)。
研究方向
納米材料、鉛、鋁等對海馬突觸可塑性的影響及其機制的研究。
主要貢獻
1、Tang M,Li Z, Chen L, Hu Y, Yang B, Ruan DY, Wang M*. The effect of quantum dots on synaptic transmission and plasticity in the hippocampal dentate gyrus area of anesthetized rats. Biomaterials,2009, 30:4948-4955.
2、Mingliang Tang, Ming Wang, Tairan Xing, Jie Zeng, Di-Yun Ruan. Mechanisms of unmodified CdSe quantum dots-Induced elevation of cytoplasmic calcium levels in rat primary cultured hippocampal neurons .Biomaterials,2008,29(33):4383-91.
3、Luo L, Chen WH, Wang M, Zhu DM, She JQ, Ruan DY. Modulation of long-term potentiation by individual subtypes of muscarinic acetylcholine receptor in the rat dentate gyrus. Hippocampus,2008,18 (10):989-995.
4、 Wang M, Chen WH, Zhu DM, She JQ, and Ruan DY. Effects of carbachol on lead-induced impairment of the long-term potentiation/depotentiation in rat dentate gyrus in vivo. Food and Chemical Toxicology, 2007,45:412-418.
5、 Wang M, Chen JT, Ruan DY, Xu YZ. The influence of developmental Period of aluminum exposure on synaptic plasticity in the adult rat dentate gyrus in vivo. Neuroscience, 2002,113(2) : 411-419.
6、 Wang M, Ruan DY, Chen JT, Xu YZ. Lack of effects of vitamin E on aluminum-induced deficit of synaptic plasticity in the rat dentate gyrus in vivo. Food and Chemical Toxicology ,2002,40(3) :1-8.
7、 Wang M, Chen JT, Ruan DY. Vasopressin reverses aluminum-induced impairment of synaptic plasticity in the rat dentate gyrus in vivo. Brain Research, 2001,899 (1-2) :193-200.