楊帆[楊帆河南科技大學]

楊帆(1982-),漢族,男,博士,河北秦皇島人。現為河南科技大學動物科技學院教師,主講本科生《獸醫藥劑學》、《獸醫藥物動力學》、《獸藥殘留分析》及研究生《高級獸醫藥理學》等課程。

楊帆(1982-),漢族,男,博士,河北秦皇島人。2007年7月畢業於瀋陽農業大學動物醫學專業,獲得“校優秀畢業生”榮譽稱號;同年9月,開始在華南農業大學獸醫學院攻讀基礎獸醫學碩士學位,研究方向為獸醫藥理學與毒理學,主要從事獸藥新製劑研究;2009年9月提前攻讀博士學位,專業為基礎獸醫學,研究方向為獸醫藥理學與毒理學,主要從事了藥物代謝、獸醫藥物代謝動力學、獸藥殘留檢測及獸藥新製劑開發等研究,期間參與了973項目“畜禽產品中有害物質的消長規律研究”(2009CB118805)第五子項目、國家自然基金項目“鴨疫里氏桿菌耐藥分子機制的研究和快速檢測方法的建立”(31072169)和十一五科技支撐項目“獸用抗菌藥物新製劑的研製與套用”(2006BAD31B06)等研究。

自2012年7月起,到河南科技大學動物科技學院工作,主要從事獸醫藥劑學、獸藥殘留檢測和獸醫藥物代謝動力學的教學和科研工作,研究方向為獸醫藥物代謝動力學、獸藥殘留檢測、獸醫新製劑開發。曾在《Br Poult Sci》、《J Vet Sci》、《J Vet Pharmacol Ther》、《Food Addit Contam Part A Chem Anal Control Expo Risk Assess》、《Res Vet Sci》、《Vet Microbiol》、《J Chromatogr B Analyt Technol Biomed Life Sci》及《Agricultural Sciences in China》等國際SCI收錄期刊上發表論文近20篇。近五年來發表相關論文如下:

1. Yang, F., Sun, N., Zhao, Z.S., Wang, G.Y. & Wang, M.F. (2015) Pharmacokinetics of doxycycline after a single intravenous, oral or intramuscular dose in Muscovy ducks (Cairina moschata). Br Poult Sci, 56(1), 137-142

2. Yang, F., Sun, N., Liu, Y.M. & Zeng, Z.L. (2015) Estimating danofloxacin withdrawal time in broiler chickens based on physiologically based pharmacokinetics modeling. J Vet Pharmacol Ther, 38(2), 174-182.

3. Yang, F., Kang, J., Yang, F., Zhao, Z., Kong, T. & Zeng, Z. (2015) Preparation and evaluation of an enrofloxacin microsphere and its tissue distribution in rats. J Vet Sci. ( published online)

4. Yang, F., Yang, Y.R., Wang, L., Huang, X.H., Qiao, G. & Zeng, Z.L. (2014) Estimating marbofloxacin withdrawal time in broiler chickens using a population physiologically based pharmacokinetics model. J Vet Pharmacol Ther, 37(6), 579-588.

5. Yang, F., Li, Z.L., Shan, Q. Zeng, Z.L. (2014) Pharmacokinetics of doxycycline in tilapia ( Oreochromis aureus × Oreochromis niloticus) after intravenous and oral administration. J Vet Pharmacol Ther, 37(4), 388-393.

6. Yang, F., Huang, X. H., Li, G. H., Ni, H. J., Zhao, Y. D., Ding, H. Z. & Zeng, Z. L. (2013) Estimating tulathromycin withdrawal time in pigs using a physiologically based pharmacokinetics model. Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 30(7), 1255-1263.

7. Yang, F., Li, G. H., Meng, X. B., Wang, L. Q., Huang, X. H., Shan, Q., Zeng, D. P., Ding, H. Z. & Zeng, Z. L. (2013) Pharmacokinetic interactions of flunixin meglumine and doxycycline in broiler chickens. J Vet Pharmacol Ther, 36(1), 85-88.

8. Yang, F., Sun, N., Sun, Y. X., Shan, Q., Zhao, H. Y., Zeng, D. P. & Zeng, Z. L. (2013) A physiologically based pharmacokinetics model for florfenicol in crucian carp and oral-to-intramuscular extrapolation. J Vet Pharmacol Ther, 36(2), 192-200.

9. Yang, F., Liu, H. W., Li, M., Ding, H. Z., Huang, X. H. & Zeng, Z. L. (2012) Use of a monte carlo analysis within a physiologically based pharmacokinetic model to predict doxycycline residue withdrawal time in edible tissues in swine. Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 29(1), 73-84.

10.Li, G., Yang, F. ( 共同第一作者 ), He, L., Ding, H., Sun, N., Liu, Y., Liu, Y., Shan, Q., Li, Y. & Zeng, Z. (2012) Pharmacokinetics of mequindox and its metabolites in rats after intravenous and oral administration. Res Vet Sci, 93(3), 1380-1386.

11.Shan, Q., Yang, F., Wang, J., Ding, H., He, L. & Zeng, Z. (2014) Pharmacokinetic/pharmacodynamic relationship of cefquinome against pasteurella multocida in a tissue-cage model in yellow cattle. J Vet Pharmacol Ther, 37(2):178-185.

12.Shan, Q., Wang, J., Yang, F., Ding, H., Liang, C., Lv, Z., Li, Z. & Zeng, Z. (2013) Pharmacokinetic/pharmacodynamic relationship of marbofloxacin against pasteurella multocida in a tissue-cage model in yellow cattle. J Vet Pharmacol Ther, 37(3):222-230.

13.Li, Y., Zhao, N., Zeng, Z., Gu, X., Fang, B., Yang, F., Zhang, B. & Ding, H. (2013) Tissue deposition and residue depletion of cyadox and its three major metabolites in pigs after oral administration. J Agric Food Chem, 61(39): 9510-9515.

14.Sun, N., Liu, J. H., Yang, F., Lin, D. C., Li, G. H., Chen, Z. L. & Zeng, Z. L. (2012) Molecular characterization of the antimicrobial resistance of riemerella anatipestifer isolated ducks. Vet Microbiol, 158(3-4), 376-83.

15.Ding, H., Liu, Y., Zeng, Z., Si, H., Liu, K., Liu, Y., Yang, F., Li, Y. & Zeng, D. (2012) Pharmacokinetics of mequindox and one of its major metabolites in chickens after intravenous, intramuscular and oral administration. Res Vet Sci, 93(1), 374-377.

16.Shan, Q., Liu, Y. M., He, L. M., Ding, H. Z., Huang, X. H., Yang, F., Li, Y. F. & Zeng, Z. L. (2012) Metabolism of mequindox and its metabolites identification in chickens using lc-ltq-orbitrap mass spectrometry. Journal Of Chromatography B-Analytical Technologies In the Biomedical And Life Sciences, 881-82(15),96-106.

17.Liu, Y. M., Liu, Y. C., Ding, H. Z., Fang, B. H., Yang, F., Shan, Q. & Zeng, Z. L. (2011) Pharmacokinetics of mequindox and its metabolites in swine. Agricultural Sciences In China, 10(12), 1968-1976.

目前主持國家自然基金(青年基金)一項,參與國家自然基金(面上項目)一項。主要研究方向為獸醫藥物代謝動力學(以傳統房室模型和生理藥動學模型為主)、獸醫製劑學、獸藥殘留檢測、獸醫毒理學等。尤其擅長於生理藥動學模型的建立、最佳化及評價,目前已建立了多種獸藥在不同動物體內的生理藥動學模型用於預   測獸藥殘留。

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