![李小明[武漢同濟醫院放射科主任醫師]](/img/7/94e/nBnauM3XxQjM5MTM0QTOxIDN0UTMyITNykTO0EDMwAjMwUzL0kzL2gzLt92YucmbvRWdo5Cd0FmLyE2LvoDc0RHa.jpg "李小明[武漢同濟醫院放射科主任醫師]")
擅長領域
在全國率先開展了各類關節炎影像診斷的臨床新技術新業務工作，取得的成績位於國際前列，已為大量患者解決了眾多疑難問題。主要擅長於：各種慢性關節炎（類風濕性關節炎、強直性脊柱炎、退行性骨關節炎、痛風性關節炎、其它各種關節炎等），因代謝、血液系統疾病引起的骨關節病變，骨缺血性壞死，肌骨關節外傷，骨腫瘤和軟組織腫瘤，骨關節感染性病變，骨軟骨發育異常等的影像學診斷。
學術兼職
全球綜合性影像診斷雜誌影響因子排名第二《Investigative Radiology》（在美國出版）在中國的唯一編委。國家自然科學基金二審專家。中華放射學會骨關節專業委員會副主任委員。《European Radiology》、《Journal of Magnetic Resonance Imaging》、《Journal of Neurology》等雜誌的審稿專家。
研究項目
(一) 3項在研國家自然科學基金項目：
1. 國家自然科學基金重點項目“椎間盤細胞及分子生物力學應答機制的影像學研究”（項目批准號： 31630025, 經費：307萬， 時間：2017.1至2021.12）；
2. 國家自然科學基金重大國際合作項目“SpA/AS的免疫學發病機制和早期病理改變特徵的影像學研究”（項目批准號：81320108013, 經費：280萬元, 時間：2014.1至2018.12）；
3. 國家自然科學基金面上項目“早期類風濕性關節炎的滑膜炎發病機制的影像學研究” （項目批准號：81571643， 經費：78萬，時間：2016.1至2019.12）。
（二）5項已結題國家自然科學基金項目：
1. 國家自然科學基金面上項目 “小兒股骨頭骨骺缺血的早期磁共振診斷方法” （項目批准號：30370430，經費：18萬元，時間：2004.01至2006.12）；
2. 國家自然科學基金面上項目“MR彈性成像檢測損傷性關節軟骨力學性質變化的研究”（項目批准號：30670605，經費： 30萬元， 時間：2007.01至2009.12）；
3.國家自然科學基金面上項目“生長板內個體軟骨細胞的分子顯微磁共振成像研究”（項目批准號：30870701，經費： 35萬元， 時間：2009.01至2011.12）；
4.國家自然科學基金面上項目“軟骨終板早期退變的μMRI研究” （項目批准號：81071133，經費：34萬元，時間：2011.01至2013.12）
5. 國家自然科學基金面上項目“骺板軟骨細胞力學應答的顯微磁共振成像研究” （項目批准號：31170899，經費： 60萬元，時間：2012.01至2015.12）。
（三） 1項在研同濟醫院轉化醫學項目：
同濟醫院十大轉化醫學研究項目“早期椎間盤退行性變的磁共振成像研究”（項目批准號：2016ZHYXXM007， 經費：50萬，時間：2017.1至2018.12）
獲獎情況
曾獲湖北省科技進步三等獎及全軍科技進步三等獎。
主要論文
以第一作者或通訊作者發表了SCI期刊論文30餘篇。
(1) Wu Gang, Yang Jun, Zhang Tianjing, Morelli John N, Giri Shivram, Li Xiaoming*, Tang Wenlin. The diagnostic value of non-contrast enhanced quiescent interval single shot (QISS) magnetic resonance angiography at 3T for lower extremit rial disease, in comparison to CT angiography. Journal of Cardiovascular Magnetic Resonance, 2016 Oct 20; 18(1):71. DOI 10.1186/s12968-016-0294-6
(2) Wu Gang, Jin Teng, Li Ting, Morelli John, Li Xiaoming*. High spatial resolution time-resolved magnetic resonance angiography of lower extremity tumors at 3T: Comparison with computed tomography angiography. Medicine. 2016 Sep; 95(37): e4894
(3) Ran J, Liu Y, Sun D, Morelli J, Zhang P, Wu G, Sheng Y, Xie R, Zhang X, Li X*. The diagnostic value of biexponential apparent diffusion coefficients in myopathy. J Neurol. 2016 Jul; 263(7):1296-302.
(4) Zhang Ping, Yu Kaihu, Guo Ruimin, Ran Jun,Liu Yao,Morelli John, Runge A Val, Li Xiaoming*. Comparing the diagnostic utility of sacroiliac spectral CT and MRI in axial spondyloarthritis. Br J Radiol. 2016; 89(1059): 20150196
(5) Zhang P, Yu KH, Guo RM, Ran J, Liu Y, Morelli J, Runge VM, Li XM*. A novel diagnostic method (spectral computed tomography of sacroiliac joints) for axial spondyloarthritis. J Formos Med Assoc. 2016 Aug; 115(8):658-64.
(6) Shen Y, Goerner F, Runge VA, Hao D, Hu D, Li X*. T1 relaxivities of Gadolinium-Based Magnetic Resonance Contrast Agents in Human Whole Blood at 1.5, 3 and 7 Tesla. Investigative Radiology. 2015 May; 50(5):330-338.
(7) Zhu T, Ai T, Zhang W, Li T, Li X*. Segmental Quantitative MR Imaging Analysis of Diurnal Variation of Water Content in the Lumbar Intervertebral Discs. Korean J Radiol. 2015; 16(1):139-145.
(8) Zhang P, Yu K, Guo R, Shah S, Morelli JN, Runge VA, Li X*. Ankylosing spondylitis: correlations between clinical and MRI indices of sacroiliitis activity. Clin Radiol. 2015 Jan; 70(1):62-6.
(9) Ai T, Yu K, Gao L,Zhang P, Goerner F, Runge VM, Li X*. Diffusion Tensor Imaging in Evaluation of Thigh Muscles in Patients with Polymyositis and Dermatomyositis. Br J Radiol. 2014 Nov;87(1043):20140261.
(10) Ai T, Goerner F, Patel N, Trelles M, Wu G, Li X*, Runge VM. Contrast Dose, Temporal Footprint, and Spatial Resolution Tradeoffs in Dynamic Contrast-Enhanced MRA Performed in a Porcine Model of a Carotid Aneurysm. Journal of computer assisted tomography. Jan 2013;37(1):105-110
(11) PAN Chu, HU Dao-yu, ZHANG Wei， LI Xiao-ming*. Role of diffusion-weighted imaging in early ankylosing spondylitis. Chin Med J 2013;126 (4):668-673.
(12) Morelli JN, Runge VM, Ai F, Zhang W, Li X*, Schmitt P, McNeal G, Michaely H, Schoenberg SO, Miller M, Gerdes CM, Sincleair ST, Spratt H, Attenberger UI. MR Evaluation of Renal Artery Stenosis in a Swine Model: Performance of Low-Dose Gadobutrol versus Gadoterate Meglumine with Comparison to DSA. Investigative Radiology. 2012; 47(6). 2012; 47(6):376-382.
(13) Tao Ai, Abraham P, Frank G, Mathias N, Zbigniew G, Siddharth J,Miguel T,Raleigh FJ, Ronald W, Xiaoming Li * ,Val M R . SEMAC-VAT and MSVAT-SPACE Sequence Strategies for Metal Artifact Reduction in 1.5T Magnetic Resonance Imaging. Investigative Radiology. 2012; 47(5): 267-276.
(14) Morelli JN, Ai F, Runge VM, Zhang W, Li X*, et al. Time-resolved MR angiography of renal artery stenosis in a swine model at 3 Tesla using gadobutrol with digital subtraction angiography correlation. J Magn Reson Imaging. 2012; 36(3):704-13.
(15) Fei Ai, Tao Ai, Xiaoming Li*, Daoyu Hu, Wei Zhang, John N. Morelli. Value of diffusion-weighted magnetic resonance imaging in early diagnosis of ankylosing spondylitis. Rheumatology nternational. 2012; 32(12):4005-13 .
(16) Ai Tao，Zhang Wei，Priddy N.K.，Xiaoming Li*. Diagnostic performance of CUBE MRI sequences of the knee compared with conventional MRI. Clinical Radiology. 2012; 67 :e58-e63.
(17) Ai Fei, YuCheng, ZhangWei, Morelli John, Kacher Daniel, Li Xiaoming*. MR Imaging of The Knee Osteoarthritis With Pain. J Huazhong Univ Sci. 2010; 30（2）: 248-254.
(18) Li X, Yu C, Wu H, Daniel K, Hu D, Xia L, Pan C, Xu A, Hu J, Wang L, Peng W, Li F. Prospective comparison of 3D FIESTA versus fat-suppressed 3D SPGR MRI in evaluating knee cartilage lesions. Clin Radiol. 2009; 64 (10):1000-1008.
(19) Li X, Peng WJ, Wu H, Kacher D, Xia LM, Ai F, Li F, Xiong W. MRI findings of injured articular cartilage of the knee with surgical correlation. Chin Med J (Engl). 2009 Nov 5; 122(21):2624-2630.
(20) Li X, Qi J, Xia L, Li H, Hu J, Yu C, Pen W, Guan J, Hu D. Diffusion MRI in Ischemic Epiphysis of the Femoral Head:An Experimental Study. J Magn Reson Imaging. 2008 Aug; 28(2):471–477.
(21) Li X, Qi J, Xia L, Yu C, Peng W, Hu X, Hu D, Feng D, Hu J, Qiu L, Li H. Dynamic gadolinium-enhanced MRI in early ischaemia of the proximal femoral epiphysis--a preliminary study. Clin Radiol. 2008 Oct; 63(10):1149-1159.
(22) Li X, Xiong W, Hu DY, Yu C, Peng WJ, Hu JW, Feng DY, Hu XM, Li HL, Qiu L, Li F. Dynamic gadoteridol-enhanced MR imaging in the end of growing long bone of piglets. Chin Med J (Engl). 2008 Oct 5; 121(19):1932-1938.
(23) Menezes NM., Li X*, Olear EA, Connolly SA, Zurakowski D, Foley M, Shapiro F, Jaramillo D. Gadolinium-Enhanced Images of the Growing Piglet Skeleton: Ionic versus Nonionic Contrast Agent. Radiology. 2006 May; 239(2): 406-414.
(24) Li X, Hu J, Zhen H, Tang L, Xu A. Early reversible ischemia of femoral head epiphysis in piglets on gadolinium-enhanced MRI: an experimental study. J Huazhong Univ Sci Technolog Med Sci. 2006;26(4):482-484.
(25) Li X, Wang R, Qi J, Tang L. Gadolinium-enhanced MR imaging of epiphyseal and metaphyseal marrow in normal piglets. J Huazhong Univ Sci Technolog Med Sci. 2005;25(4):461-463
(26) Li X，Wang R, Li Y, Tang L, Hu J, Xu A. Gadolinium-enhanced MR imaging in developing epiphysis of normal piglets : an experimental study. J Huazhong Univ Sci Technolog Med Sci.2005;25(2):209-211
(27) LI Xiaoming, WANG Ren-fa, LI Yong-gang, TANG Li-hua, YANG Bo. Growth Cartilage of Piglet: Correlation between MRI Characteristics and Histologic Findings and Measurements of T1 and T2 Relaxation Time. Journal of Nanjing Nedical University. 2004; 18(5) :244-249.
(28) Li X，Wang R, Li Y, Tang L, Xu A, Hu J. MRI characteristics and transverse relaxation time measurements in normal growing cartilage. J Huazhong Univ Sci Technolog Med Sci. 2004;24(4):411-413
(29) Xiaoming Li , Xavier Leclerc , Thierry Huisman, A. Gregory Sorensen.DT- MRI of Central Nervous System: Clinical Applications. CNS SPECTRUMS. July 2002；7 （7）：535-541.
(30) Xiaoming Li, Chengyuan Wang，et al. MR Imaging of the Pancreas. Journal of Xi’an Medical University. 2000; Vol.12 No.1 40-45.
