惠永正

惠永正

惠永正,男,1939年12月生,江蘇蘇州人,1962年畢業於北京大學化學系。後就職於中科院上海有機化學研究所、國家科委等。

基本信息

人物經歷

惠永正圖片 惠永正圖片

1959.9-1962.7 北京大學

1962.9- 中科院上海有機化學研究所

1982.2-1983.1 美國 University of North Carolina at Chapel Hill

1983.2-1983 12 美國 Rutgers University

1991.1- 國家科委

主要工作成就

惠永正早期從事物理有機化學研究,系統地研究了糖澱粉及其衍生物作為宿主體系的宿主-客體化學, 隨後研究領域擴展到計算機化學和微泡體化學。近年來主要從事微泡體化學和糖化學研究,包括長鏈、多氟代長鏈化物的微泡體的性質和生物合功能模擬: 複雜寡糖的化學合成及糖綴合物中糖鏈與生物功能之間關係的研究。早年曾從事計算機化學和微環境效應研究,曾獲全國科學大會獎(1978),中科院科學進步一等獎(1986),國家自然科學三等獎(1988),和中科院發明一等獎(1997)。至今共發表論文71篇。共培養碩士研究生7,博士研究生6名,合作培養博士生8名 。

發表論文

1. Inter-Domain Movenment of Spin Lables in the Vesicle Monolayers of Hybride bolaamphiphiles.

B.Y.Z.Hui, Supramolecular Chem., 1995, 5, 193-195

2. Direct Facile Tetrahydrofuranylation of Alcohols in p-TsCl/NaH/THF System.

B.Y.Z.Hui, Synth. Commun., 1995, 25, 2037

3. A New Highly Regioselective Reaction of Unprotected Sugars for Chemical Synthesis of -Acyl-D-glucopyranosides.

J.Xia, Y.Z.Hui, Synth. Commun., 1995, 25, 2235-2251

4. An Efficient and Stereospecific Synthesis of 1-Stearoyl-2-[(z,z,z)-9,12,15-Linolenoyl]-sn-Glycerophosphocholine and its Bioactivity.

J.Xia, Y.Z.Hui, Bioorg. Med. Chem. Lett., 1995, 5(17),1919-1922

5. A New Strategy for the Stereoselective Synthesis of 2,3-Dideoxy-3-Fluoro-D-Ribofuranose Derivatives.

Z.W.Guo, B.G.Huang, W.J.Xia, Y.Z.Hui, S..Lang, Chin. J. Chem., 1995, 13,363

6. Chemical Synthesis of a Commonly Occurring Saponin Trisaccharide: a -L-Rhaminosyl-(1-4)-b nosyl-(1-6)-D-Glucopyranose.

M.Z.Liu, Z.W.Guo, Y.Z.Hui, Carbonhydr. Lett., 1995, 1, 387-392

7. An Efficient and Stereospecific Synthesis of 1-Palmitoyl-2-[(z,z,z)-9,12,15-Linolenoyl]-sn-Glycerophophocholine.

J.Xia, Y.Z.Hui, Chin. Chem. Lett., 1995, 6(10), 863-866

8. A General Method for the Synthese of Ether Phospholipids with a -Linolenic Acid and Their Properties.

J.Xia, Y.Z.Hui, Bioorg. Med. Chem. Lett., 1995, 5(23), 2815-2820

9. A New Highly Regioselective Reaction of Unprotected Sugars for Chemical Synthesis of Methyl-6-D-Acyl-D-Glycopyranoside by Means of Chlorophosphoric Acid Diethyl Ester as Condensing Reagent.

J.Xia, Y.Z.Hui, Synth. Commun, 1996, 26(2), 269-278

10. A Convenient Method for Highly Selective Deprotection of Benzylidene Acetals from Sugars

J.Xia, Y.Hui, Synth. Commum., 1996, 26(5), 881-886

11. The TMSOTf-Promoted "One Pot" -Glycosidations of Peracetylated Chitobiose.

B.Q. Ouyang, Y.Z.Hui, J. Carbohydr. Chem., 1996, 15(3), 297-302

12. Chemical Synthesis of (3-SO3Na) GlcNAc b 1-3Fuc b 1-OMe: The Oligocaccharide Involved in the Cell Aggregation of the Sponge Microcina Prolifera.

Z.W.Guo, S.J.Deng, Y.Z.Hui, J. Carbohydr. Chem., 1996, 15(8), 965-974

13. A New Strategy for the Stereoselective Syntheses of C-Glycosyl Compounds of b -Pentapyranoses.

Z.W.Guo, Y.Z.Hui, Synth. Commun., 1996, 26(11), 2067-2073

14. Supramolecular Assemblies from Single-Chain Hydrocarbon Fluorocarbon Hybrid Bolaamphiphiles.

B. Y.Z.Hui, Chin. J. Chem., 1996, 14(2), 171-179

15. Structural Study on a Bioactive Fructan from the Root of Achyranthes Bidentata Blume.

B. G.Y.Tian, Y.Z.Hui, Chin. J. Chem., 1996, 13(6), 539-544

16. A One-Step Procedure for Facile, Selective Synthesis of Protected D-Glucopyranosides with Free 2-C Hydroxyl Group Starting from Peracetylated b-D-Glucopyranose.

; M.Z.Liu, H.N.Fan, Z.W.Guo, Y.Z.Hui, Chin. J. Chem., 1996, 14(2), 190-192

17. One-Step Glycosylation and Selective Deprotection of Peracetylated Monosaccharides for Facile Syntheses of Allyl Glycosides with a Free C-2 Hydroxyl Group.

M.Z.Liu, H.N.Fan, Z.W.Guo, Y.Z.Hui, Carbonhydr. Res., 1996, 290, 233-237

18. A New Reaction for One-pot, Selective Mono-O-Glycosylations of 9,10- Dihydroxyphenanthrene Under Mild Conditions.

Z.W.Guo, Y.Z.Hui, Chin.Chem.Lett., 1996, 7(5), 423-424

19. Isolation and Structure Elucidation of a Polysaccharide with Radiation-Protective Activity from Spinulina Platensis.

Z.W.Guo, Y.Z.Hui, Chin.J. Chem., 1996, 14(3), 279-285

20. A One-Step Procedure for Facile Preparation of D-Glucopyranosides with a Free 2-OH from Peracetylated b -D-Glucopyranose.

M.Z.Liu, H.N.Fan, Z.W.Guo, Y.Z.Hui, J. Carbohydr. Chem., 1996, 15(9), 1139-1145

21. The Stereospecific Synthesis of Mixed-acid Phospholipids with Polyunsaturated Fatty Acid from D-mannitol.

J. Xia, Y. Z. Hui, Tetrahedron: Asymmetry, 1997, 3, 451-485

22. Recent Progress of Saponin Research.

M.Z.Liu, Z.W.Guo, Y.Z.Hui, Natural Product Research and Development, 1997, 9(2), 81-85

23. A Facial Regioselective 1,6-O-Diacetylation Method of Methyl glycopyranosides and Their Dimethyl Phosphonates.

G.T.Zhang, Z.W.Guo, Y.Z.Hui, Synth. Commun., 1997, 27(11), 1907-1918

24. First Total Synthesis of Tricolorin A.

S., Q.Q.Ouyang, Z.W.Guo, , Y.Z.Hui, Angew. Chem. Int. Ed. Engl., 1997, 36, 2344-2346.

25. A Synthesis of Tricolorin A.

S., Q.Q.Ouyang, Z.W.Guo, Y.Z.Hui, J.Org.Chem., 1997, 62, 8400-8405.

26. Synthesis and Antitumor Activities of Diosgenyl Glycosides.

M.Z.Liu, , Z.W.Guo, Y.Z.Hui, Carbohydr. Lett., 1997, 2,423-428.

27. Conformational Analysis of Two Diosgenyl Saponins.

M.Z.Liu, , M.B.Chen, C.L.Feng, Y.Z,Hui, Chin. Chem. Lett., 1997, 8, 785-788.

28. A New Method for the Cleavage of Carbohydrate Benzylidene Acetyl by Ceric (IV) Ammonium Nitrate in CH3CN-H2O (10:1).

S., Q.Q.Ouyang, Z.W.Guo, , Y.Z.Hui, Chin. Chem. Lett., 1997, 8, 841.

29. Efficient One-Step Methyl Esterification of Carboxylic Acid and Deacetylation by BF3OEt2-MeOH.

S., Q.Q.Ouyang, Z.W.Guo, , Y.Z.Hui, Chin. Chem. Lett., 1997, 8, 843.

30. What is the Sugar Chains¡¯ Function in Saponin.

M.Z.Liu, Z.W.Guo, Y.Z.Hui, Youji Huaxue, 1997, 17, 307.

31. Recent Progress on Resin Glycoside Research.

S., Q.Q.Ouyang, Z.W.Guo, Y.Z.Hui, Youji Huaxue, 1997, 17(4), 1

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