實驗室簡介
安徽綠色材料化學實驗室2004年經安徽省教育廳批准成立，其前身是1999年成立的淮北煤炭師範學院材料化學與物理實驗室。實驗室以化學系有機化學、分析化學省級重點學科、理論化學研究室和物理系凝聚態物理院級重點學科、納米材料研究所以及數學系和計算機系的計算數學、套用數學院級重點學科為主要依託。綠色材料化學省級重點實驗室目前的主要包括有機高分子材料化學與物理；無機納米材料的製備、物性與套用；功能薄膜材料；計算材料化學四個研究方向。材料化學與物理實驗室現有固定研究人員40人，其中教授12人，副教授18人，講師10人；固定研究人員中有博士36人。近五年，實驗室共承擔各類科研項目76項，其中國家自然科學基金項目16項，省部級項目 32 項，科研項目經費總額1000 萬元；獲得各類獎勵 56 項，其中省部級以上獎勵39 項；申請專利6項；發表論文 548 篇，其中被SCI、EI、ISTP收錄 278篇。現任實驗室學術委員會主任錢逸泰教授，實驗室主任王磊教授。
研究方向及帶頭人
1、有機無機雜化材料的製備及套用 帶頭人 王磊教授
2、光催化材料的製備與套用 陳士夫教授
3、功能高分子材料 劉結平教授
4、功能薄膜材料 戴建明教授
科研項目
1. 基於碳氫鍵活化的噁（噻）唑類雜環C2位官能化及其雜原子導向的反應
國家自然科學基金 (No. 21202057)，2013−2015
2. 形貌可控的磁性納米粒子負載催化劑的製備及催化的有機合成反應
國家自然科學基金 (No. 21172092)，2012−2015
3. 負載膦-過渡金屬配合物的製備及催化的有機合成反應
國家自然科學基金 (No. 21002039)，2011−2013
4. 廉價過渡金屬鐵催化的有機串聯反應及套用
國家自然科學基金 (No. 20972057)，2010−2012
5. 多功能化離子液體的合成及在有機合成中的套用
國家自然科學基金 (No. 20772043)，2008−2010
6. 脯氨酸和其寡肽接枝載體的製備及在不對稱催化反應中的套用
國家自然科學基金 (No. 20572031)，2006−2008
7. 有機-無機雜化材料負載活性鎳在潔淨反應介質催化有機合成反應的研究及套用
國家自然科學基金 (No. 20372024)，2004−2006
8. 綠色有機合成方法學的研究
教育部高校留學回國人員科研項目，2011−2013
9. 過渡金屬催化的唑類雜環基於碳氫鍵活化的化學轉化及套用
安徽省自然科學基金（1308085MB25） , 2013−2014
10 氮雜環卡賓及其金屬配合物的負載策略和在有機合成中的套用
安徽省教育廳自然科學研究重大項目（2010ZD009）, 2010−2011
代表性學術論文
(1) Dengke Li, Min Wang,* Jie Liu, Qiong Zhao, and Lei Wang .* Cu-Catalyzed Decarboxylative Acylation of Acyl C–H of Formamides with α-Oxocarboxylic Acids Leading to α-Ketoamides. Chem. Commun. 2013, 49, 3640–3642.
(2) Jie Liu, Wei Chen, and Lei Wang.* Synthesis of 2-Selenyl(sulfenyl)benzofurans via Cu-Catalyzed Tandem Reactions of 2-( gem-Dibromovinyl)phenols with Diorganyl Diselenides(disulfides). RSC Advances 2013, 3, 4723–4730.
(3) Kai Luo, Lingguo Meng, Yicheng Zhang, Xiuli Zhang,* and Lei Wang .* A Stereocontrolled 1,2-Addition Reaction of Tetrazoles with Alkyl Propiolates for the Synthesis of Highly Functionalized Enamines. Adv. Synth. Catal. 2013, 355, 765–780.
(4) Qiong Zhao, Tao Miao, Xiaobin Zhang, Wei Zhou and Lei Wang .* Direct Use of Formamides as Amino Group Sources via C–N Bond Cleavage: A Catalytic Oxidative Synthesis of α-Ketoamides from Acetophenones and Formamides under Metal-Free Conditions. Org. Biomol. Chem. 2013, 11, 1867 – 1873.
(5) Lin Yu, Pinhua Li, and Lei Wang.* Copper-Promoted Decarboxylative Direct C3-Acylation of N-Substituted Indoles with α-Oxocarboxylic Acids. Chem. Commun. 2013, 49, 2368–2370.
(6) Hongji Li, Pinhua Li, and Lei Wang .* Direct Access to Acylated Azobenzenes via Pd-Catalyzed C–H Functionalization and Further Transformation into an Indazole Backbone. Org. Lett. 2013, 15, 620–623.
(7) Wei Chen, Pinhua Li, Tao Miao, Ling-Guo Meng,* and Lei Wang .* An Efficient Tandem Elimination–Cyclization–Desulfitative Arylation of 2-( gem-Dibromovinyl)phenols(thiophnols) with Sodium Arylsulfinates. Org. Biomol. Chem. 2013, 11, 420–424.
(8) Xiaobin Zhang, Min Wang, Yicheng Zhang, and Lei Wang .* A Novel and Metal-free Approach towards α-Ketoamides using TBHP/I-Promoted Tandem Reaction of Amines with β-Diketones via C–C Bond Cleavage. RSC Advances 2013, 3, 1311–1316.
(9) Pinhua Li, Yong Ji, Wei Chen, Xiuli Zhang, and Lei Wang .* The Facile Synthesis of 2-Bromoindoles via CsCO-Promoted Intramolecular Tandem Cyclization of 2-( gem-Dibromovinyl)anilines under Transition-metal-free Conditions. RSC Advances 2013, 3, 73–78.
(10) Wei Zhou, Hongji Li, and Lei Wang .* Direct Carbo-Acylation Reactions of 2-Arylpyridines with α-Diketones via Pd-Catalyzed C–H Activation and Selective C(sp2)–C(sp2) Cleavage. Org. Lett. 2012, 14, 4594–4597.
(11) Yicheng Zhang, Min Wang, Pinhua Li, and Lei Wang .* Iron-Promoted Tandem Reaction of Anilines with Styrene Oxides via C–C Cleavage for the Synthesis of Quinolines. Org. Lett. 2012, 14, 2206–2209.
(12) Jie Liu, Pinhua Li, Wei Chen, and Lei Wang.* An Efficient Synthesis of 2-Bromo(chloro)-3-selenyl(sulfenyl)indoles via Tandem Reactions of 2-( gem-Dibromo(chloro)vinyl)anilines with Diselenides(disulfides). Chem. Commun. 2012, 48, 10052–10054.
(13) Chengliang Li, Pinhua Li, Jin Yang, and Lei Wang .* Palladium-Catalyzed Deamidative Arylation of Azoles with Arylamides through a Tandem Decarbonylation/C-H Functionalization. Chem. Commun. 2012, 48, 4214–4216.
(14) Ling-Guo Meng, and Lei Wang .* EtN-Promoted Tandem Ring-Opening Reaction of N-Tosylaziridines with Terminal Alkynoates: A Straightforward Synthesis of Functionalized Enamines. Chem. Commun. 2012, 48, 3242–3244.
(15) Pinhua Li, Lei Wang ,* Lei Zhang, and Guan-Wu Wang.* Magnetic Nanoparticles Supported Palladium: A Highly Efficient and Reusable Catalyst for the Suzuki, Sonogashira, and Heck Reactions. Adv. Synth. Catal. 2012, 354, 1307–1318.
(16) Jie Liu, Wei Chen, Yong Ji, and Lei Wang .* A Highly Efficient Tandem Reaction of 2-( gem-Dibromovinyl)phenols(thiophenols) with Organosilanes to 2-Arylbenzofurans(thiophenes). Adv. Synth. Catal. 2012, 354, 1585–1592.
(17) Xiaobin Zhang, and Lei Wang.* TBHP/I-Promoted Oxidative Coupling of Acetophenones with Amines at Room Temperature under Metal-Free and Solvent-Free Conditions for the Synthesis of α-Ketoamides. Green Chem. 2012, 14, 2141–2145.
(18) Jin Yang, and Lei Wang .* Synthesis and Characterization of Dinuclear NHC–Palladium Complexes and Their Applications in the Hiyama Reactions of Aryltrialkyoxysilanes with Aryl Chlorides. Dalton Transactions 2012, 41, 12031–12037.
(19) Wei Zhou, Wei Chen, and Lei Wang.* A Highly Efficient One-Pot Reaction of 2-( gem-Dibromovinyl)phenols(thiophenols) with KFe(CN) to 2-Cyanobenzofurans(thiophenes). Org. Biomol. Chem. 2012, 10, 4172–4178.
(20) Wei Zhou, Yicheng Zhang, Pinhua Li, and Lei Wang.* Synthesis of ( Z)-3-Aryloxy-acrylonitriles, ( E)-3-Aryloxy-acrylonitriles and 3-Cyanobenzofurans through the Sequential Reactions of Phenols with Propiolonitriles. Org. Biomol. Chem. 2012, 10, 7184–7196.
(21) Lei Zhang, Pinhua Li, Hongji Li,* and Lei Wang .* Recyclable Magnetic Nanoparticles Supported Palladium Catalyst for the Hiyama Reaction of Aryltrialkyoxysilanes with Aryl Halides. Catal. Sci. Technol. 2012, 2, 1859–1864.
(22) Chengliang Li, Lei Wang,* Pinhua Li,* and Wei Zhou. Palladium-Catalyzed ortho-Acylation of Acetanilides with Aldehydes via Direct C-H Bond Activation. Chem. Eur. J. 2011, 17, 10208–10212.
(23) Tao He, Lin Yu, Lei Zhang, Lei Wang,* and Min Wang.* Direct C2-Alkylation of Azoles with Alcohols and Ethers through Dehydrogenative Cross-Coupling under Metal-Free Conditions. Org. Lett. 2011, 13, 5016–5019.
(24) Shihua Wang, Pinhua Li, Lin Yu, and Lei Wang.* Sequential and One-Pot Reactions of Phenols with Bromoalkynes for the Synthesis of ( Z)-2-Bromovinyl Phenyl Ethers and Benzo[ b]furans. Org. Lett. 2011, 13, 5968–5971. (Highlighted by: SYNFACTS 2012, 8(1), 0030)
(25) Wei Chen, Yicheng Zhang, Lei Zhang, Min Wang* and Lei Wang.* A Highly Efficient TBAF-Promoted Intramolecular Cyclization of gem-Dibromoolefins for the Synthesis of 2-Bromobenzofurans(thiophenes). Chem. Commun. 2011, 47, 10476–10478.
(26) Tao He, Hongji Li, Pinhua Li, and Lei Wang.* Direct Amidation of Azoles with Formamides via Metal-free C-H Activation in the Presence of tert-Butyl Perbenzoate. Chem. Commun. 2011, 47, 8946– 8948.
(27) Chengliang Li, Yicheng Zhang, Pinhua Li,* and Lei Wang.* Palladium-Catalyzed Oxidative Cyclization of 3-Phenoxyacrylates: An Approach to Construct Substituted Benzofurans from Phenols. J. Org. Chem. 2011, 76, 4692–4696.
(28) Ling-Guo Meng, Ni-Lin Ge, Ming-Ming Yang, and Lei Wang.* Cyclization Reaction of 2-Azido-1-(2-hydroxyphenyl)ethanones with Terminal Alkynoates Catalyzed by 4-Dimethylaminopyridine (DMAP): Synthesis of 2-Aminobenzofuran-3(2H)-one Derivatives. Eur. J. Org. Chem. 2011, 3403–3406.
(29) Bo Wang, Shihua Wang, Pinhua Li,* and Lei Wang.* Iron-catalyzed Regio- and Stereoselective Addition of Acid Chlorides to Alkynes. Chem. Commun. 2010, 46, 5891–5893. (Highlighted by: SYNFACTS 2010, 11, 1288)
(30) Lei Wang,* Jie Liu, Tao Miao, Wei Zhou, Pinhua Li, Kai Ren, and Xiuli Zhang.* Sugar-Based Pyrrolidine as a Highly Enantioselective Organocatalyst for Asymmetric Michael Addition of Ketones to Nitrostyrenes. Adv. Synth. Catal. 2010, 352, 2571–2578.
(31) Kai Ren, Min Wang, and Lei Wang .* FeX-Promoted Intermolecular Addition of Benzylic Alcohols to Aromatic Alkynes: A Mild and Efficient Strategy for the Synthesis of Alkenyl Halides. Eur. J. Org. Chem. 2010, 565–571.
(32) Pinhua Li, Yicheng Zhang, and Lei Wang.* Iron-Catalyzed Ligand-Free Three-Component Coupling Reactions of Aldehydes, Terminal Alkynes, and Amines. Chem. Eur. J. 2009, 15, 2045–2049. (Most Accessed Articles in 2009, Number 4 of Top 5)
(33) Min Wang, Kai Ren, and Lei Wang .* Iron-Catalyzed Ligand-Free C-Se (Te) Coupling of Arylboronic Acids with Diselenides and Ditellurides. Adv. Synth. Catal. 2009, 351, 1586–1594.
(34) Yicheng Zhang, Pinhua Li, Min Wang, and Lei Wang.* Indium-Catalyzed Highly Efficient Three-Component Coupling of Aldehyde, Alkyne, and Amine via C-H Bond Activation. J. Org. Chem. 2009, 74, 4364–4367.
(35) Kai Ren, Min Wang, and Lei Wang .* Lewis Acid InBr-Catalyzed Arylation of Diorgano Diselenides and Ditellurides with Arylboronic Acids. Org. Biomol. Chem. 2009, 7 , 4858–4861.
(36) Pinhua Li, L ei Wang ,* Min Wang, and Feng You. A Novel Gold(I) Iodide Catalyzed Sonogashira Reactions. E ur. J. Org. Chem. 2008, 5946–5951. (Most Accessed Articles in 11/2008, Number 2 of Top 12)
(37) Min Wang, Pinhua Li, and Lei Wang.* Silica Immobilized NHC–Cu: An Efficient and Reusable Catalyst for A-Coupling (Aldehyde–Alkyne–Amine) under Solventless Reaction Conditions. Eur. J. Org. Chem. 2008, 2255–2261. (Highlighted by: SYNFACTS 2008, 7, 0777)
(38) Pinhua Li, Lei Wang,* Min Wang, and Yicheng Zhang. Polymer Immobilized Pyrrolidine-based Chiral Ionic Liquids as Recyclable Organocatalysts for Asymmetric Michael Additions to Nitrostyrenes under Solvent-free Reaction Conditions. Eur. J. Org. Chem. 2008, 1157–1160. (Highlighted by: SYNFACTS 2008, 5, 0548)
(39) Pinhua Li, and Lei Wang.* An Amine-, Copper- and Phosphine-free Sonogashira Coupling Reaction Catalyzed by Immobilization of Palladium in Organic–inorganic Hybrid Materials. Adv. Synth. Catal. 2006, 348, 681–685.
(40) Lei Wang,* Pinhua Li, and Yicheng Zhang. The Sonogashira Coupling Reaction Catalyzed by Ultrafine Nickel(0) Powder. Chem. Commun. 2004, 514–515. (Most Accessed Articles in 2/2004, Top 10)
