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The third edition contains major improvements over the previous two editions. I have updated references. Each reaction is now supplemented with two to three representative examples in synthesis to showcase its synthetic utility. As Emil Fi-scher stated:“Science is not an abstraction; but as a product of human endeavor it is inseparably bound up in its development with the personalities and fortunes of those who dedicate themselves to it .” To that end, I added biographical sketches Furthemore,I have significantly beefed up the subject index to help the reader na-vigate the book more easily.