人物經歷
1992.4-1996.3日本東京農工大學學士學位。
1996.4-1998.3日本東京農工大學碩士學位。
1998.4-2001.3日本東京農工大學博士學位。
2001.4-2001.6日本產業技術綜合研究所博士後研究員。
2001.7-2006.6美國紐約州立大學研究員。
2006.7-2007.6日本國立產業合研究所(AIST)糖鎖研究中心助理研究員。
2007.7-2011.5日本福島縣立醫科大學助理教授。
2011.7-江南大學生物工程學院教授。
研究方向
糖生物學(glycobiology)、生物工程(biotechnology)、分子生物學(molecular biology)。
主要貢獻
主要論著
1. Elias, EV., Quiroga, R., Gottig, N., Nakanishi, H., Nash, TE., Neiman, AM. and Lujan, HD. Characterization of SNARES determines the absence of a typical Golgi apparatus in the ancient eukaryote Giardia lamblia. J Biol Chem . 283:35996-36010. (2008). ( IF5.328 )。
2. Yang, HJ., Nakanishi, H., Liu, S., McNew, JA. And Neiman, AM. Binding interactions can control SNARE specificity in vivo. J Cell Biol . 183:1089-1100. (2008). ( IF5.328 )。
3. Suda, Y., Nakanishi, H., Mathieson, EM., and Neiman, AM. Alternative modes of organellar segregation during sporulation in Saccharomyces cerevisiae. (2007). Eukaryot Cell. 11: 2009-2017. ( IF3.086 )。
4. Pablo-Hernando, ME., Arnaiz-Pita, Y., Nakanishi, H., Dawson, D., Del Rey, F., Neiman, AM. and Vazquez de Aldana, CR. Cdc15 is required for spore morphogenesis independently of Cdc14 in Saccharomyces cerevisiae. (2007). Genetics. 177: 281-293. ( IF3.889 )。
5. Zeniou-Meyer, M., Zabari, N., Ashery, U., Chasserot-Golaz, S., Haeberle, AM., Demais, V., Bailly, Y., Gottfied, I., Nakanishi, H., Neiman, AM., Du, G., Frohman, MA., Bader, MF. and Vitale, N. 2007. PLD1 production of phosphatidic acid at the plasma membrane promotes exocytosis of large dense-core granule at a late stage. J Biol Chem. 282: 21746-21757. ( IF5.328 )。
6. Nakanishi, H., Suda, Y. and Neiman, AM. Erv14 family cargo receptors are necessary for ER exit during sporulation in Saccharomyces cerevisiae. (2007). J Cell Sci. 120: 908-916. ( IF6.14 )。
7. Nakanishi, H., Morishita, M., Schwartz, C., Coluccio, A., Engebrecht, JA. and Neiman, AM. Phospholipase D and the SNARE Sso1p are necessary for vesicle fusion during sporulation in yeast. (2006). J Cell Sci. 119: 1406-1415. ( IF6.14 )。
8. Winters, MJ., Lamson, RE., Nakanishi, H., Neiman, AM. and Pryciak, PM. A Membrane Binding Domain in the Ste5 Scaffold Synergizes with GBinding to Control Localization and Signaling in Pheromone Response. (2005). Mol Cell. 20: 21-32. ( IF14.608 )。
9. Nakanishi, H., de los Santos, P. and Neiman, AM. Positive and negative regulation of a SNARE protein by control of intracellular localization. (2004). Mol Biol Cell. 15: 1802-1815. ( IF5.979 )。
10. Suda, Y., Tachikawa, H., Yokota, A., Nakanishi, H., Yamashita, N., Miura, Y. and Takahashi, N. 2003. Saccharomyces cerevisiae QNS1 codes for NAD(+) synthetase that is functionally conserved in mammals. Yeast. 20: 995- 1005. ( IF1.805 )。
11. Nakanishi, H., Nakayama, KI., Yokota, A., Tachikawa, H., Takahashi, N. and Jigami, Y. 2001. Hut1 proteins identified in Saccharomyces cerevisiae and Schizosaccharomyces pombe are functional homologues involved in the protein folding process at the endoplasmic reticulum. Yeast. 18: 543-554. ( IF1.805 )。
12. Tachikawa, H., Funahashi, W., Takeuchi, Y., Nakanishi, H., Nishihara, R., Katoh, S., Gao, XD., Mizunaga, T. and Fujimoto, D. 1997. Overproduction of Mpd2p suppresses the lethality of protein disulfide isomerase depletion in a CXXC sequence dependent manner. Biochem Biophys Res Commun. 239: 710-714. ( IF2.548 )。
科研項目
2006-2009新エネルギー產業技術総合開発機構 糖鏈機能套用技術開發糖鎖機能活用技術開発項目配合主任;經費:2500萬日元。
2007-2008日本文部科學省 大量蛋白質成熟過程中控制機制的研究成熟過程における分泌系カーゴ蛋白質のゲーティングパーミッション機構の研究,項目配合主任;經費:1410萬日元。