雷新響

雷新響

雷新響,副研究員,碩士研究生導師。

個人概況

,,在中國科學院成都生物研究所獲博士學位,,主持國家自然科學基金等項目,在Nucl. Acids Res. Stem Cell. Organic letters, MRC等期刊上發表SCI論文30餘篇,2006年入選溫州“551人才工程”,2010.3-2011.2在耶魯大學學習, 2011.2月在Scripps Florida Institute訪問交流 。

sphenanthera. Helvetica Chimica Acta. 94 (3): 491-496, 2011 IF: 1.435

主要項目

主持國家自然科學基金,浙江省自然科學基金,科技廳等項目。

科研課題

本課題組招收有機化學,分析化學,藥物化學專業研究生,共同從事天然藥物(植物源,微生物源)提取、分離、結構鑑定及生物學意義研究;從事設計、合成、構建有序介質在有機分析化學(天然產物複雜結構,有機小分子手性分析)中的套用;從事NMR新方法和新技術的開發和套用研究。熱忱歡迎勤奮好學,對自然充滿好奇心的同學加盟。同時歡迎喜歡探索未知的優秀本科生朋友加入,課餘、假期參與科研工作。

代表論著

1、Ma, QZ; Ma, MS; Tian, HY; Ye, XX; Xiao, HP; Chen, LH*; Lei, XX* A Novel Amine Receptor Based on the Binol Scaffold Functions as a Highly Effective Chiral Shift Reagent for Carboxylic Acids. Organic Letters, 2012, 14 (23): 5813-5815. (影響因子: 5.86)

2、He, DH; Zhou, Y; Ding, LS; Lei, XX; Xiao, HP; Qi, HY; Xu, HX.; Gymnotheloids A — C, three lignan alkaloids from Gymnotheca chinensis. J. Org. Chem., 2012, 77, 8435−8443. (影響因子: 4.45)

3、Lei, XX; Xu, J; Ma, W; Qiao, C; Newman, MA; Hammond, SM; Huang, YQ. Determinants of mRNA recognition and translation regulation by Lin28. Nucl. Acids Res., 2012, 40, 5174-5184. (影響因子: 8.02)

4、Zhu, XO; Jun J; Lei, XX; Chen, XJ. Rapid determination of enantiomeric excess of protected amino acids by catalytic amounts of chiral reagent. Anal. Methods, 2012, 4, 1920-1923. (影響因子: ~1.5)

5、Liu, L; Ye, MD; Hu, Xg; Yu, XC*; Zhang, LX; Lei, XX*. Chiral Solvating Agents for Carboxyilc Acids Based on Salen Moiety. Tetrahedron: Asymmetry, 2011, 22, 1667-1771. (影響因子: ~2.5)

6、Jin, JY; Jing, W; Lei, XX; Feng, C. Peng, SP; Boris-Lawrie, K; Huang, YQ. Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes. Nucl. Acids Res., 2011,39(9): 3724-3734. (影響因子: 8.02)

7、Jiang, Y; Yang, GZ*; Chen, Y; Liao, MC; Liu, XM; Chen, S; Liu, L; Lei, XX*. Terpenes fromSchisandra sphenanthera. Helvetica Chimica Acta, 2011, 94 (3): 491-496. (影響因子: ~1.5)

8、Peng, SP; Chen, LL; Lei, XX; Yang, Y; Lin, HF; Carmichael, GG; Huang, YQ. Genome-wide Studies Reveal that Lin28 Enhances the Translation of Genes Important for Growth and Survival of Human Embryonic Stem Cells. Stem Cells, 2011, 29, 496-504. (影響因子: 7.8)

9、Han, C; Liu, CP; Zhou, YF; Xia, BQ; Zhu, ZO; Lei, XX; Shen, Y. Microwave-assisted extraction and determination of cyanuric acid residue in infant formula samples by liquid chromatography–tandem mass spectrometry. Food Chemistry, 2011, 127, 875–879. (影響因子: ~3.5)

10、Shen, Y; Han, C.; Jiang, YX; Zhou, XJ; Zhu, ZO; Lei, XX. Rapid quantification of four major bioactive alkaloids in Corydalis decumbens (Thunb.) Pers. by pressurised liquid extraction combined with liquid chromatography-triple quadrupole linear ion trap mass spectrometry.Talanta, 2011, 84(4): 1026-1031. (影響因子: ~3.5)

11、Lei, XX*; Liu, L; Chen, XJ; Yu, XC; Ding, LS; Zhang, AJ*. Pattern-Based Recognition for Determination of Enantiomeric Excess, Using Chiral Auxiliary Induced Chemical Shift Perturbation NMR. Organic Letters, 2010, 12 (11): 2540-2543. (影響因子: 5.86)

12、Ye, XX; Lei, XX*; Chen, ZF; Zhang, LX; Zhang, AJ*. In Situ Measurement of the Enantiomeric Excess of Alcohols and Amines under Asymmetric Reduction Reaction by 1H NMR. Organic Letters,2010, 12 (14): 3238-3241. (影響因子: 5.86)

13、Ai, Y; Yang, GZ*; Liu, JC; Chen, Y; Liu, L; Lei, XX*. Synthesis and structure elucidation of five new pyrimido[5,4-c]quinoline-4(3H)-one derivatives using 1D and 2D NMR spectroscopy.Magn. Reson. Chem.,2010, 48 (12): 955-959. (影響因子: ~1.5)

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