人物經歷
2010年至今: 華東師範大學, 生命科學學院, 教授, 博士生導師；
2009年: 聖路易斯華盛頓大學, 生物醫學工程系, 博士後研究助理;
2004-2008年: 中國科學技術大學, 生命科學學院, 獲得結構生物學博士學位;
2000-2004年: 中國科學技術大學, 高分子科學與工程系, 獲得理學學士學位。
研究方向
樹枝形分子等生物材料的設計及其在生物醫學中的套用研究;
納米生物材料在早期癌症診斷及靶向治療中的套用研究；
基於樹枝形分子的主-客體系統的設計及其在藥物運輸中的套用；
生物兼容的納米材料在早期腫瘤診斷及治療中的套用研究；
將多維核磁等技術套用於納米藥物劑型設計及最佳化的研究。
社會兼職
2010年起擔任國際刊物Current Drug Discovery Technologies的Regional Editor‚曾擔任Open Journal of Pharmacology‚ Current Drug Discovery Technologies‚ Der Pharma Chemica‚ Local and Regional Anesthesia 等多個國際刊物編委（Editorial Board Member）‚ 先後70多次被邀請為30多個國際知名刊物的審稿人。
國際刊物、出版物編輯 (Editors):
2010年至今: Current Drug Discovery Technologies (Regional Editor);
2010年: 應著名出版公司John Wiley & Sons, Inc.邀請擔任“Dendrimer-based Drug Delivery Systems: From Theory to Practice”一書的主編(Editor-in chief)。
國際刊物編委 (Editorial Board Members):
2009年至今: Open Journal of Pharmacology;
2008年至今: Local and Regional Anesthesia;
2009-2010年: Current Drug Discovery Technologies;
2009年至今: Der Pharma Chemica.
主要成果
自開展研究工作起一直致力於樹枝形分子等納米生物材料的研究工作，已經在Nature Materials‚ Chemical Society Reviews, Journal of the American Chemical Society‚ Journal of Physical Chemistry B等國際知名刊物發表第一作者/通訊作者SCI論文30多篇‚論文影響因子總和達160，被製藥科學和藥物化學領域知名刊物Chemical Society Reviews, Frontiers in Bioscience‚ Journal of Pharmaceutical Sciences‚ European Journal of Medicinal Chemistry等邀請撰寫專題綜述6篇，所發表第一/通訊作者論文已有7篇（次）被雜誌選為出版當年、當季度的熱門或引用次數最多的文章。
在樹枝形分子領域的很多工作已經受到國際同行專家的認可和關注，被國際著名出版社John Wiley & Sons 邀請作為主編編寫專題著作“Dendrimer-based Drug Delivery Systems: from Theory to Practice”(2011年正式出版)，論文被國內外其他課題組公開引用500多次。近3年代表性論文如下：（*通訊作者)
1) Yavuz MS†‚ Cheng YY†‚ Chen JY†‚ Cobley CM‚ Zhang Q‚ Rycenga M‚ Xie JW‚ Kim C‚ Schwartz AG‚ Wang LV‚ Xia YN*‚ Gold Nanocages Covered by Smart Polymers for Controlled Release with Near-infrared Light. Nature Materials‚ 2009‚ 8(12): 935-939. (†共同第一作者; 2009年影響因子29.504; 論文自發表以來被 Science Daily‚ The New York Times‚ R & D Magazines‚ Nanomedicine等多家權威媒體‚雜誌Highlight).
2) Zhao LB‚ Wu QL‚ Cheng YY*‚ Zhang JH‚ Wu JH‚ Xu TW*. High-Throughput Screening of Dendrimer-Binding Drugs‚ Journal of the American Chemical Society‚ 2010‚ 132(38): 13182-13184‚ 2010. (2009年影響因子8.58).
3) Feng XY‚ Cheng YY*‚ Yang K‚ Zhang J‚ Wu Q‚ Xu TW*. Host-Guest Chemistry of Dendrimer-Drug Complexes‚ 5. Insights into the Design of Formulations for Noninvasive Delivery of Heparin Revealed by Isothermal Titration Calorimetry and NMR Studies‚ Journal of Physical Chemistry B‚ 2010‚ 114 (34): 11017-11026.
4) Cheng YY*‚ Xu ZH‚ Ma ML‚ Xu TW*‚ Dendrimers as Drug Carriers: Applications in Different Routes of Drug Administration‚ Journal of Pharmaceutical Sciences‚ 2008‚ 97(1): 123-143. (2008年被選為該雜誌十大最熱門文章之一; 2009年再次被選為該雜誌十大被引次數最多的文章).
5) Fang M‚ Cheng YY*‚ Zhang JH‚ Wu QL‚ Hu JJ‚ Zhao LB‚ Xu TW*‚ New Insights into the Interactions between Dendrimers and Surfactants: 4. Fast Exchange/Slow Exchange Transitions in the Structure of Dendrimer-Surfactant Aggregates‚ Journal of Physical Chemistry B‚ 2010‚ 114(18): 6048-6055.
6) Yang K‚ Cheng YY*‚ Feng XY‚ Zhang JH‚ Wu QL‚ Xu TW*‚ New Insights into the Interactions between Dendrimers and Mixed Micelles: 5. Formation of Miscellaneous Mixed Micelles Revealed by a Combination of 1H NMR‚ Diffusion‚ and NOE Analysis‚ Journal of Physical Chemistry B‚ 2010‚ 114(21): 7265-7273.
7) Hu JJ‚ Fang M‚ Cheng YY*‚ Zhang JH‚ Wu QL‚ Xu TW‚ Host-Guest Chemistry of Dendrimer-Drug Complexes: 4. An In-depth Look into the Binding/Encapsulation of Guanosine Monophosphate by Dendrimers‚ Journal of Physical Chemistry B‚ 2010‚ 114(21): 7148-7157.
8) Cheng YY*‚ Wu QL‚ Li YW‚ and Xu TW*‚ External Electrostatic Interaction versus Internal Encapsulation between Cationic Dendrimers and Negatively Charged Drugs: Which Contributes More to Solubility Enhancement of the Drugs? Journal of Physical Chemistry B‚ 2008‚ 112: 8884-8890.
9) Hu JJ‚ Cheng YY*‚ Wu QL‚ Zhao LB‚ Xu TW*‚ Host-Guest Chemistry of Dendrimer-Drug Complexes: 2. Effects of Molecular Properties of Guests and Surface Functionalities of Dendrimers‚ Journal of Physical Chemistry B‚ 2009‚ 113(31): 10650 - 10659.
10) Zhao LB‚ Cheng YY*‚ Hu JJ‚ Wu QL‚ Xu TW*‚ Host-Guest Chemistry of Dendrimer-Drug Complexes: 3. Competitive Binding of Multi-drugs to a Single Dendrimer‚ Journal of Physical Chemistry B‚ 2009‚ 113(43): 14172-14179.
11) Cheng YY*‚ Li YW‚ Wu QL‚ Xu TW*‚ New Insights into the Interactions between Dendrimers and Surfactants by Two Dimensional NOE NMR Spectroscopy‚ Journal of Physical Chemistry B‚ 2008‚ 112(40): 12674-12680.
12) Hu JJ‚ Cheng YY*‚ Ma YR‚ Wu QL‚ Xu TW*‚ Host-Guest Chemistry and Physico-chemical Properties of Dendrimer-Mycophenolic Acid Complexes‚ Journal of Physical Chemistry B‚ 2009‚ 113(1): 64-74.
13) Cheng YY*‚ Wu QL‚ Li YW‚ Hu JJ‚ Xu TW*‚ New Insights into the Interactions between Dendrimers and Surfactants: 2. Design of New Drug Formulations Based on Dendrimer-Surfactant Aggregates‚ Journal of Physical Chemistry B‚ 2009‚ 113(24): 8339-8346.
14) Wu QL‚ Cheng YY*‚ Hu JJ‚ Zhao LB‚ Xu TW*‚ New Insights into the Interactions between Dendrimers and Surfactants: 3. Size- and Hydrophobicity-Dependent Encapsulation of Bile Salts‚ Journal of Physical Chemistry B‚ 2009‚ 113: 12934-12943.
15) Cheng YY‚ Wang JR‚ Rao TL‚ He XX‚ Xu TW*‚ Pharmaceutical Applications of Dendrimers: Promising Nanocarriers for Drug Delivery‚ Frontiers in Bioscience‚ 2008‚ 13: 1447-1471.
16) Yang WJ‚ Li YW‚ Cheng YY*‚ Wu QL‚ Wen LP‚ Xu TW*‚ Evaluation of Phenylbutazone and Poly(amidoamine) Dendrimers Interactions by a Combination of Solubility‚ 2D-NOESY NMR‚ and Isothermal Titration Calorimetry Studies‚ Journal of Pharmaceutical Sciences‚ 2009‚ 98(3): 1075-1085.
17) Cheng YY*†‚ Li YW†‚ Wu QL‚ Zhang JH‚ Xu TW*‚ Generation-Dependent Encapsulation/Electrostatic Attachment of Phenobarbital Molecules by Poly(amidoamine) Dendrimers: Evidence from 2D-NOESY Investigations‚ European Journal of Medicinal Chemistry‚ 2009‚ 44(5): 2219-2213. (†共同第一作者).
18) Yang WJ‚ Cheng YY*‚ Xu TW*‚ Wang XY‚ Wen LP*‚ Targeting Cancer Cells with Dendrimer-Biotin Conjugates‚ European Journal of Medicinal Chemistry‚ 2009‚ 44(2): 862-868.
19) Cheng YY*‚ Xu TW*‚ The Effect of Dendrimers on the Pharmacodynamic and Pharmacokinetic behaviors of Non-covalently or Covalently Attached Drugs‚ European Journal of Medicinal Chemistry‚ 2008‚ 43: 2291-2297.
20) Cheng YY*‚ Man N‚ Xu TW‚ Fu RQ‚ Wang XY‚ Wang XM‚ Wen LP*‚ Transdermal Delivery of Non-Steroidal Anti-Inflammatory Drugs Mediated by Polyamidoamine (PAMAM) Dendrimers‚ Journal of Pharmaceutical Sciences‚ 2007‚ 96(3): 595-602.
