孟萌[南開大學藥學院副教授]

孟萌,1981年出生,南開大學藥學院副教授。

招生方向:藥物化學、藥物分析、微生物。

人物經歷

孟萌副教授 孟萌副教授

2003年7月畢業於北京大學藥學院藥學專業, 獲學士學位,同年9月於北京大學藥學院直接攻讀藥劑學專業博士學位,從事蛋白多肽藥物納米給藥系統、載體系統與生物大分子間相互作用研究,2008年6月獲博士學位。2008年7月到南開大學藥學院工作,加入免疫分析課題組跟隨郗日沫教授從事小分子有害殘留物的快速免疫檢測工作。

自就職以來,一直從事食品中的小分子有害殘留物的快速免疫檢測研究工作,在小分子殘留物的半抗原結構修飾和改造,完全免疫原的合成,抗體的製備、純化和定性研究,以及快速免疫檢測方法的建立方面都擁有豐富的經驗和成功的經歷。除傳統酶聯免疫檢測法外,所在課題組對化學發光免疫,電化學感測器,螢光免疫檢測,免疫磁珠檢測等手段都有一定的成功研究經歷。目前主持一項國家自然科學基金青年基金項目。

研究方向

生物抗體技術,免疫分析檢測,食品殘留檢測。

主要貢獻

發表SCI收錄文章14篇。

1. Xiaoling Fu, Meng Meng*, Yu Zhang, Yongmei Yin, Xiangsheng Zhang*, Rimo Xi*, Chemiluminescence enzyme immunoassay using magnetic nanoparticles for detection of neuron specific enolase in human serum, Analytica Chimica Acta, 2012, Doi:10.1016/j.aca.2012.02.007.

2. Taichang Zhang, Huyin Xue, Bo Zhang, Yu Zhang, Pei Song, Xi Tian, Yue Xing, PengWang, Meng Meng* and Rimo Xi*, Determination of folic acid in milk, milk powder and energy drinks by an indirect immunoassay, J Sci. Food Agric., 2012, 92, DOI:10.1002/jsfa.5625.

3. Yabin Wang, Fangyang He, Yuping Wan, Meng Meng*, Jing Xu, Yuanyang Zhang, Jian Yi, Caiwei Feng, Shanliang Wang, Rimo Xi*. An indirect competitive enzyme-linked immuno-sorbent assay (ELISA) to detect nitroimidazoles in food products, Food Additives & Contaminants: Part A, 2011, 28: 619-626.

4. Meng Meng, Rimo Xi*. Review: Current development in analyzing drug residue in foods and food products. Analytical Letters, 2011, 44: 2543–2558.

5. Zhaozhen Cao, Shengxin Lu, Jinting Liu, Jinhua Zhan, Meng Meng*, Rimo Xi*. Preparation of anti-Lomefloxacin Antibody and Development of an Indirect Competitive Enzyme-Linked Immunosorbent Assay for Detection of Lomefloxacin Residue in Milk. Analytical Letters, 2011, 44 (6), 1100-1113.

6. Zhaozhen Cao, Meng Meng*, Shengxin Lu, Rimo Xi*. Development of an indirect chemiluminescent competitive ELISA to detect danofloxacin residues in milk. Analytical Letters, 2011, 44 (6), 1077–1084.

7. Yuanyang Zhang, Fangyang He, Yuping Wan, Meng Meng*, Jing Xu, Jian Yi, Yabin Wang, Caiwei Feng, Shanliang Wang, Rimo Xi*. Generation of anti-trenbolone monoclonal antibody and establishment of an indirect competitive enzyme-linked immunosorbent assay for detection of trenbolone in animal tissues, feed and urine. Talanta, 2011, 83, 732-737.

8. Jing Xu, Yuanyang Zhang, Jian Yi, Meng Meng*, Rimo Xi*. Preparation of anti-Sudan Red monoclonal antibody and development of an indirect competitive enzyme-linked immunosorbent assay for detection of Sudan Red in Chili Jam and Chili Oil, Analyst, 2010,135(10), 2566-2572.

9. Weiwei Yin, Jinting Liu, Weihua Li, Wei Liu, Meng, Meng*, Yuping Wan, Caiwei Feng, Shanliang Wang, Xiao Lu, Rimo Xi*. Preparation of monoclonal antibody for melamine and development of an indirect competitive ELISA for melamine detection in raw milk, milk Powder and animal Feeds, J. Agric. Food Chem., 2010, 58, 8152-8157.

10. Wei Liu, Weihua Li, Weiwei Yin, Meng Meng*, Yuping Wan, Caiwei Feng, Shanliang Wang and Rimo Xi∗. Preparation of monoclonal antibody and development of an indirect competitive ELISA for the detection of chlorpromazine residue in chicken and swine liver, J Sci Food Agr, 2010, 90, 1789-1795.

11. Meng Meng, Yulan Zhang, Shengxin Lu, Jinting Liu, Jinhua Zhan, Rimo Xi*. Preparation of anti-salbutamol antibody based on a new designed immunogen and development of a heterologous indirect cELISA for detection of salbutamol residue. Acta Pharmaceutica Sinica, 2010, 45 (4), 442-450.

12. Jian Yi, Meng Meng, Zhongqiu Liu, Jinfang Zhi, Yuanyang Zhang, Jing Xu, Yabin Wang, Jinting Liu*, Rimo Xi*, Development of an electrochemical immunoassay for detection of gatifloxacin in swine urine, J Zhejiang Univ-Sci B, 2012, 13(2):118-125.

13. Xiao Lu, Hong Zheng, Xiuqing Li, Xuexia Yuan, Hui Li, Ligang Deng, Hong Zhang, Wenzheng Wang, Guosheng Yang*, Meng Meng, Rimo Xi*, Hassan Y. Aboul-Enein*, Detection of ractopamine residues in pork by surface plasmon resonance-based biosensor inhibition immunoassay, Food Chem,, 2012, 130: 1061–1065.

14. Weihua Li, Meng Meng, Huyin Xue, Wei Liu, Weiwei Yin, Jing Xu, Fangyang He, Yuping Wan, Caiwei Feng, Shanliang Wang, Xiao Lu, Jinting Liu*, Rimo Xi*. Preparation of an anti-diethylstilbestrol monoclonal antibody and development of an indirect competitive ELISA for detection of diethylstilbestrol in animal tissue, urine and bile. Chinese Science Bulletin, 2011, 56(8): 749–754.

15. 薛虎寅,尹永梅,張太昌,宋佩,田溪,張昱,孟萌*,郗日沫*,偶氮類合成色素檢測技術的研究進展,生物技術進展,2012 (In press).

16. 張太昌,孟萌,宋佩,田溪,薛虎寅,張昱,尹永梅*,郗日沫*,食物中維生素分析方法的研究進展,生物技術進展,2012 (In press).

17. 宋佩,孟萌,Sergei A Eremin,張太昌,田溪,薛虎寅,張昱,尹永梅*,郗日沫*,螢光偏振免疫分析方法快速檢測沙拉沙星殘留,分析化學,2012 (In press).

授權或申報的專利

1. 郗日沫,張太昌,孟萌,尹永梅,薛虎寅,宋佩,田溪,邢玥,王鵬,徐志環(2012)一種生物素的酶聯免疫檢測試劑盒。

2. 郗日沫,田溪,孟萌,尹永梅,張波,宋佩,薛虎寅,張太昌,邢玥,王鵬,徐志環(2012)一種鄰苯二甲酸二乙酯螢光偏振免疫檢測試劑盒。

3. 郗日沫,邢玥,薛虎寅,孟萌,張太昌,宋佩,田溪,王鵬(2011)一種日落黃的酶聯免疫檢測試劑盒,國家發明專利,國家知識產權局。

4. 郗日沫,張太昌,孟萌,薛虎寅,徐靜,張元陽(2011)一種葉酸的酶聯免疫檢測試劑盒,國家發明專利,國家知識產權局。

5. 郗日沫,薛虎寅,孟萌,張太昌,張元陽,徐靜,王亞賓(2010)一種酸性橙Ⅱ的酶聯免疫檢測試劑盒,國家發明專利,國家知識產權局。

6. 郗日沫,王亞賓,孟萌,徐靜,張元陽,張太昌,薛虎寅(2010)利用單抗檢測萊克多巴胺殘留的間接化學發光酶聯免疫試劑盒,國家發明專利,國家知識產權局。

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